1. ICD-10-CM Codes
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2. D50-D89
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3. D55-D59
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4. D56-
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5. 2023 ICD-10-CM Diagnosis Code D56.1

2023 ICD-10-CM Diagnosis Code D56.1

Beta thalassemia

2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

• D56.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2023 edition of ICD-10-CM D56.1 became effective on October 1, 2022.
• This is the American ICD-10-CM version of D56.1 - other international versions of ICD-10 D56.1 may differ.

• Beta^+^ thalassemia
• Beta^0^ thalassemia
• Hemoglobin c beta^+^ thalassemia
• Hemoglobin c beta^0^ thalassemia
• Hemoglobin d beta^+^ thalassemia
• Hemoglobin d beta^0^ thalassemia
• Hemoglobin e beta^+^ thalassemia
• Hemoglobin e beta^0^ thalassemia
• Hgb c beta plus thalassemia
• Hgb c beta zero thalassemia
• Hgb d beta plus thalassemia
• Hgb d beta zero thalassemia
• Hgb e beta plus thalassemia
• Hgb e beta zero thalassemia
• Homozygous beta thalassemia
• Thalassemia, beta
• Thalassemia, beta plus
• Thalassemia, beta zero
• Thalassemia, beta, homozygous

• A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin a synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, cooley's anemia, mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin a synthesis is absent.
• An autosomal recessive disorder that affects the production of beta polypeptide chains which are necessary for the hemoglobin synthesis. Anemia and failure to thrive are characteristic features.

• 791 Prematurity with major problems
• 793 Full term neonate with major problems
• 811 Red blood cell disorders with mcc
• 812 Red blood cell disorders without mcc

Convert D56.1 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Type 1 Excludes: D56.3
  , D56.5
  ICD-10-CM Diagnosis Code D56.3

  Thalassemia minor

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Alpha thalassemia minor
  • Alpha thalassemia silent carrier
  • Alpha thalassemia trait
  • Beta thalassemia minor
  • Beta thalassemia trait
  • Delta-beta thalassemia minor
  • Delta-beta thalassemia trait
  • Thalassemia trait NOS

  Type 1 Excludes

  • alpha thalassemia (D56.0)
  • beta thalassemia (D56.1)
  • delta-beta thalassemia (D56.2)
  • hemoglobin E-beta thalassemia (D56.5)
  • sickle-cell trait (D57.3)
  ICD-10-CM Diagnosis Code D56.5

  Hemoglobin E-beta thalassemia

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Type 1 Excludes

  • beta thalassemia (D56.1)
  • beta thalassemia minor (D56.3)
  • beta thalassemia trait (D56.3)
  • delta-beta thalassemia (D56.2)
  • delta-beta thalassemia trait (D56.3)
  • hemoglobin E disease (D58.2)
  • other hemoglobinopathies (D58.2)
  • sickle-cell beta thalassemia (D57.4-)

• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
  ICD-10-CM Diagnosis Code D64.9

  Anemia, unspecified

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • erythroblastic
    • familial D56.1
    • of childhood D56.1
  • Cooley's D56.1 (erythroblastic)
  • familial erythroblastic D56.1
• Cooley's anemia D56.1
• Thalassemia (anemia) (disease) D56.9
  ICD-10-CM Diagnosis Code D56.9

  Thalassemia, unspecified

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Mediterranean anemia (with other hemoglobinopathy)
  • beta (severe) D56.1
    • homozygous D56.1
    • major D56.1
  • intermedia D56.1
  • major D56.1

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.