2021 ICD-10-CM Diagnosis Code D57.0

Hb-SS disease with crisis

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • D57.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2021 edition of ICD-10-CM D57.0 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of D57.0 - other international versions of ICD-10 D57.0 may differ.
Applicable To
  • Sickle-cell disease with crisis
  • Hb-SS disease with vasoocclusive pain
The following code(s) above D57.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D57.0:
  • D50-D89
    2021 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D57
    ICD-10-CM Diagnosis Code D57

    Sickle-cell disorders

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • other hemoglobinopathies (D58.-)
    Use Additional
    • code for any associated fever (R50.81)
    Sickle-cell disorders
Clinical Information
  • Broad term used to describe several different acute conditions occurring with sickle cell disease, including aplastic crisis, hemolytic crisis, and vasoocclusive crisis.
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to D57.0:
  • Code First: N08
    ICD-10-CM Diagnosis Code N08

    Glomerular disorders in diseases classified elsewhere

      2016 2017 2018 2019 2020 2021 Billable/Specific Code Manifestation Code
    Applicable To
    • Glomerulonephritis
    • Nephritis
    • Nephropathy
    Code First
    Type 1 Excludes
    • glomerulonephritis, nephritis and nephropathy (in):
    • antiglomerular basement membrane disease (M31.0)
    • diabetes (E08-E13 with .21)
    • gonococcal (A54.21)
    • Goodpasture's syndrome (M31.0)
    • hemolytic-uremic syndrome (D59.3)
    • lupus (M32.14)
    • mumps (B26.83)
    • syphilis (A52.75)
    • systemic lupus erythematosus (M32.14)
    • Wegener's granulomatosis (M31.31)
    • pyelonephritis in diseases classified elsewhere (N16)
    • renal tubulo-interstitial disorders classified elsewhere (N16)
ICD-10-CM Codes Adjacent To D57.0
D56 Thalassemia
D56.0 Alpha thalassemia
D56.1 Beta thalassemia
D56.2 Delta-beta thalassemia
D56.3 Thalassemia minor
D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
D56.5 Hemoglobin E-beta thalassemia
D56.8 Other thalassemias
D56.9 Thalassemia, unspecified
D57 Sickle-cell disorders
D57.0 Hb-SS disease with crisis
D57.00 …… unspecified
D57.01 Hb-SS disease with acute chest syndrome
D57.02 Hb-SS disease with splenic sequestration
D57.03 Hb-SS disease with cerebral vascular involvement
D57.09 …… with other specified complication
D57.1 Sickle-cell disease without crisis
D57.2 Sickle-cell/Hb-C disease
D57.20 …… without crisis
D57.21 Sickle-cell/Hb-C disease with crisis
D57.211 Sickle-cell/Hb-C disease with acute chest syndrome

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.