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ICD-10-CM Codes
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D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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D55-D59
Hemolytic anemias
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D57-
Sickle-cell disorders
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2021 ICD-10-CM Diagnosis Code D57.00
2021 ICD-10-CM Diagnosis Code D57.00
Hb-SS disease with crisis, unspecified
2016 2017 2018 2019 2020 2021 Billable/Specific Code
- D57.00 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2021 edition of ICD-10-CM D57.00 became effective on October 1, 2020.
- This is the American ICD-10-CM version of D57.00 - other international versions of ICD-10 D57.00 may differ.
Applicable To- Hb-SS disease with (painful) crisis NOS
- Hb-SS disease with vasoocclusive pain NOS
The following code(s) above
D57.00 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D57.00:
- D50-D89
2021 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanismType 2 Excludes- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - D57
ICD-10-CM Diagnosis Code D57
Sickle-cell disorders
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Type 1 Excludes- other hemoglobinopathies (D58.-)
Use Additional- code for any associated fever (R50.81)
Sickle-cell disorders - D57.0
ICD-10-CM Diagnosis Code D57.0
Hb-SS disease with crisis
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Applicable To- Sickle-cell disease with crisis
- Hb-SS disease with vasoocclusive pain
Hb-SS disease with crisis
Approximate Synonyms
- Hemoglobin s sickling disorder with crisis
- Sickle cell anemia, crisis
Clinical Information
- Broad term used to describe several different acute conditions occurring with sickle cell disease, including aplastic crisis, hemolytic crisis, and vasoocclusive crisis.
ICD-10-CM D57.00 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
- 811 Red blood cell disorders with mcc
- 812 Red blood cell disorders without mcc
Convert D57.00 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- Crisis
- Dactylitis
- Disease, diseased - see also Syndrome
- hemoglobin or Hb
- S or SS D57.1
ICD-10-CM Diagnosis Code D57.1
Sickle-cell disease without crisis
2016 2017 2018 2019 2020 2021 Billable/Specific Code
Applicable To- Hb-SS disease without crisis
- Sickle-cell anemia NOS
- Sickle-cell disease NOS
- Sickle-cell disorder NOS
- with
- vasoocclusive pain D57.00
- crisis (painful) D57.00
- sickle-cell D57.1
ICD-10-CM Diagnosis Code D57.1
Sickle-cell disease without crisis
2016 2017 2018 2019 2020 2021 Billable/Specific Code
Applicable To- Hb-SS disease without crisis
- Sickle-cell anemia NOS
- Sickle-cell disease NOS
- Sickle-cell disorder NOS
- with
- crisis (painful) D57.00
- vasoocclusive pain D57.00
ICD-10-CM Codes Adjacent To D57.00
D56.2 Delta-beta thalassemia
D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
D56.5 Hemoglobin E-beta thalassemia
D56.9 Thalassemia, unspecified
D57 Sickle-cell disorders
D57.0 Hb-SS disease with crisis
D57.00
…… unspecified
D57.01 Hb-SS disease with acute chest syndrome
D57.02 Hb-SS disease with splenic sequestration
D57.03 Hb-SS disease with cerebral vascular involvement
D57.09 …… with other specified complication
D57.1 Sickle-cell disease without crisis
D57.2 Sickle-cell/Hb-C disease
D57.21 Sickle-cell/Hb-C disease with crisis
D57.211 Sickle-cell/Hb-C disease with acute chest syndrome
D57.212 Sickle-cell/Hb-C disease with splenic sequestration
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.