2020 ICD-10-CM Diagnosis Code D57.1

Sickle-cell disease without crisis

    2016 2017 2018 2019 2020 Billable/Specific Code
  • D57.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM D57.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of D57.1 - other international versions of ICD-10 D57.1 may differ.
Applicable To
  • Hb-SS disease without crisis
  • Sickle-cell anemia NOS
  • Sickle-cell disease NOS
  • Sickle-cell disorder NOS
The following code(s) above D57.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D57.1:
  • D50-D89
    2020 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D57
    ICD-10-CM Diagnosis Code D57

    Sickle-cell disorders

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • other hemoglobinopathies (D58.-)
    Use Additional
    • code for any associated fever (R50.81)
    Sickle-cell disorders
Approximate Synonyms
  • Hb ss disease
  • Hemoglobin s sickling disorder without crisis
  • Maternal sickle cell anemia in pregnancy
  • Microhematuria due to sickle cell disease
  • Postpartum (after childbirth) sickle cell anemia
  • Postpartum sickle cell anemia
  • Priapism due to sickle cell disease
  • Proliferative retinopathy due to sickle cell disease
  • Sickle cell anemia
  • Sickle cell anemia in childbirth
  • Sickle cell anemia, without crisis
  • Sickle cell proliferative retinopathy
  • Sickle cell retinopathy
  • Sickle cell retinopathy (eye condition)
  • Sickle cell w/ microhematuria
Clinical Information
  • A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia.
  • A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin s.
  • An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red blood cells. Sickle cell anemia is caused by a mutation (change) in one of the genes for hemoglobin (the substance inside red blood cells that binds to oxygen and carries it from the lungs to the tissues). It is most common in people of west and central african descent.
  • Disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs; the clinical expression of homozygosity for hemoglobin s.
  • Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. The cells are shaped like a crescent or sickle. They don't last as long as normal, round red blood cells, which leads to anemia. The sickle cells also get stuck in blood vessels, blocking blood flow. This can cause pain and organ damage. A genetic problem causes sickle cell anemia. People with the disease are born with two sickle cell genes, one from each parent. If you only have one sickle cell gene, it's called sickle cell trait. About 1 in 12 african americans has sickle cell trait. A blood test can show if you have the trait or anemia. Most states test newborn babies as part of their newborn screening programs.
ICD-10-CM D57.1 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 811 Red blood cell disorders with mcc
  • 812 Red blood cell disorders without mcc

Convert D57.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to D57.1:
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
    ICD-10-CM Diagnosis Code D64.9

    Anemia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • Herrick's D57.1
  • Disease, diseased - see also Syndrome
  • Hemoglobinopathy (mixed) D58.2
    ICD-10-CM Diagnosis Code D58.2

    Other hemoglobinopathies

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Abnormal hemoglobin NOS
    • Congenital Heinz body anemia
    • Hb-C disease
    • Hb-D disease
    • Hb-E disease
    • Hemoglobinopathy NOS
    • Unstable hemoglobin hemolytic disease
    Type 1 Excludes
    • familial polycythemia (D75.0)
    • Hb-M disease (D74.0)
    • hemoglobin E-beta thalassemia (D56.5)
    • hereditary persistence of fetal hemoglobin [HPFH] (D56.4)
    • high-altitude polycythemia (D75.1)
    • methemoglobinemia (D74.-)
    • other hemoglobinopathies with thalassemia (D56.8)

ICD-10-CM Codes Adjacent To D57.1
D56.3 Thalassemia minor
D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
D56.5 Hemoglobin E-beta thalassemia
D56.8 Other thalassemias
D56.9 Thalassemia, unspecified
D57 Sickle-cell disorders
D57.0 Hb-SS disease with crisis
D57.00 …… unspecified
D57.01 Hb-SS disease with acute chest syndrome
D57.02 Hb-SS disease with splenic sequestration
D57.1 Sickle-cell disease without crisis
D57.2 Sickle-cell/Hb-C disease
D57.20 …… without crisis
D57.21 Sickle-cell/Hb-C disease with crisis
D57.211 Sickle-cell/Hb-C disease with acute chest syndrome
D57.212 Sickle-cell/Hb-C disease with splenic sequestration
D57.219 …… unspecified
D57.3 Sickle-cell trait
D57.4 Sickle-cell thalassemia
D57.40 …… without crisis
D57.41 Sickle-cell thalassemia with crisis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.