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ICD-10-CM Codes
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D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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D55-D59
Hemolytic anemias
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D57-
Sickle-cell disorders
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2021 ICD-10-CM Diagnosis Code D57.41
2021 ICD-10-CM Diagnosis Code D57.41
Sickle-cell thalassemia, unspecified, with crisis
2016 2017 2018 2019 2020 2021 - Revised Code Non-Billable/Non-Specific Code
- D57.41 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
- ICD-10-CM D57.41 is a revised 2021 ICD-10-CM code that became effective on October 1, 2020.
- This is the American ICD-10-CM version of D57.41 - other international versions of ICD-10 D57.41 may differ.
Applicable To- Sickle-cell thalassemia with (painful) crisis NOS
- Sickle-cell thalassemia with vasoocclusive pain NOS
The following code(s) above
D57.41 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D57.41:
- D50-D89
2021 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanismType 2 Excludes- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- D57
ICD-10-CM Diagnosis Code D57
Sickle-cell disorders
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Type 1 Excludes- other hemoglobinopathies (D58.-)
Use Additional- code for any associated fever (R50.81)
- D57.4
ICD-10-CM Diagnosis Code D57.4
Sickle-cell thalassemia
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Applicable To- Sickle-cell beta thalassemia
- Thalassemia Hb-S disease
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
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2021 (effective 10/1/2020): Revised code
- New description: Sickle-cell thalassemia, unspecified, with crisis
- 2020 description: Sickle-cell thalassemia with crisis
ICD-10-CM Codes Adjacent To D57.41
D57.21 Sickle-cell/Hb-C disease with crisis
D57.211 Sickle-cell/Hb-C disease with acute chest syndrome
D57.212 Sickle-cell/Hb-C disease with splenic sequestration
D57.213 Sickle-cell/Hb-C disease with cerebral vascular involvement
D57.218 …… with other specified complication
D57.4 Sickle-cell thalassemia
D57.41
Sickle-cell thalassemia, unspecified, with crisis
D57.411 Sickle-cell thalassemia, unspecified, with acute chest syndrome
D57.412 Sickle-cell thalassemia, unspecified, with splenic sequestration
D57.413 Sickle-cell thalassemia, unspecified, with cerebral vascular involvement
D57.418 …… with other specified complication
D57.419 Sickle-cell thalassemia, unspecified, with crisis
D57.42 …… beta zero without crisis
D57.43 Sickle-cell thalassemia beta zero with crisis
D57.431 Sickle-cell thalassemia beta zero with acute chest syndrome
D57.432 Sickle-cell thalassemia beta zero with splenic sequestration
D57.433 Sickle-cell thalassemia beta zero with cerebral vascular involvement
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
