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ICD-10-CM Codes
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D50-D89
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D55-D59
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D57-
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2023 ICD-10-CM Diagnosis Code D57.453
2023 ICD-10-CM Diagnosis Code D57.453
Sickle-cell thalassemia beta plus with cerebral vascular involvement
2021 - New Code 2022 2023 Billable/Specific Code
- D57.453 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- Short description: Sickle-cell thalassemia beta plus with cereb vascular invl
- The 2023 edition of ICD-10-CM D57.453 became effective on October 1, 2022.
- This is the American ICD-10-CM version of D57.453 - other international versions of ICD-10 D57.453 may differ.
Applicable To- HbS-beta plus with cerebral vascular involvement
- Sickle-cell beta plus with cerebral vascular involvement
Code AlsoCode Also Help
A code also note instructs that 2 codes may be required to fully describe a condition but the sequencing of the two codes is discretionary, depending on the severity of the conditions and the reason for the encounter.
The following code(s) above
D57.453 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D57.453:
- D50-D89
2023 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanismType 2 Excludes- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - D57
ICD-10-CM Diagnosis Code D57
Sickle-cell disorders
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Type 1 Excludes- other hemoglobinopathies (D58.-)
Use Additional- code for any associated fever (R50.81)
Sickle-cell disorders - D57.4
ICD-10-CM Diagnosis Code D57.4
Sickle-cell thalassemia
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
Applicable To- Sickle-cell beta thalassemia
- Thalassemia Hb-S disease
Sickle-cell thalassemia - D57.45
ICD-10-CM Diagnosis Code D57.45
Sickle-cell thalassemia beta plus with crisis
2021 - New Code 2022 2023 Non-Billable/Non-Specific Code
Applicable To- HbS-beta plus with crisis
- Sickle-cell beta plus with crisis
Sickle-cell thalassemia beta plus with crisis
ICD-10-CM D57.453 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
- 791 Prematurity with major problems
- 793 Full term neonate with major problems
- 811 Red blood cell disorders with mcc
- 812 Red blood cell disorders without mcc
Code History
- 2021 (effective 10/1/2020): New code
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
- Disease, diseased - see also Syndrome
- hemoglobin or Hb
- S or SS D57.1
ICD-10-CM Diagnosis Code D57.1
Sickle-cell disease without crisis
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- Hb-SS disease without crisis
- Sickle-cell anemia NOS
- Sickle-cell disease NOS
- Sickle-cell disorder NOS
- beta plus D57.44
ICD-10-CM Diagnosis Code D57.44
Sickle-cell thalassemia beta plus without crisis
2021 - New Code 2022 2023 Billable/Specific Code
Applicable To- HbS-beta plus without crisis
- Sickle-cell beta plus without crisis
- with
- cerebral vascular involvement D57.453
- sickle-cell D57.1
ICD-10-CM Diagnosis Code D57.1
Sickle-cell disease without crisis
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- Hb-SS disease without crisis
- Sickle-cell anemia NOS
- Sickle-cell disease NOS
- Sickle-cell disorder NOS
- thalassemia D57.40
ICD-10-CM Diagnosis Code D57.40
Sickle-cell thalassemia without crisis
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- Microdrepanocytosis
- Sickle-cell thalassemia NOS
- beta plus D57.44
ICD-10-CM Diagnosis Code D57.44
Sickle-cell thalassemia beta plus without crisis
2021 - New Code 2022 2023 Billable/Specific Code
Applicable To- HbS-beta plus without crisis
- Sickle-cell beta plus without crisis
- with
- cerebral vascular involvement D57.453
ICD-10-CM Codes Adjacent To D57.453
D57.43 Sickle-cell thalassemia beta zero with crisis
D57.431 Sickle-cell thalassemia beta zero with acute chest syndrome
D57.432 Sickle-cell thalassemia beta zero with splenic sequestration
D57.433 Sickle-cell thalassemia beta zero with cerebral vascular involvement
D57.438 …… with other specified complication
D57.44 …… beta plus without crisis
D57.45 Sickle-cell thalassemia beta plus with crisis
D57.451 Sickle-cell thalassemia beta plus with acute chest syndrome
D57.452 Sickle-cell thalassemia beta plus with splenic sequestration
D57.453
Sickle-cell thalassemia beta plus with cerebral vascular involvement
D57.458 …… with other specified complication
D57.8 Other sickle-cell disorders
D57.81 Other sickle-cell disorders with crisis
D57.811 Other sickle-cell disorders with acute chest syndrome
D57.812 Other sickle-cell disorders with splenic sequestration
D57.813 Other sickle-cell disorders with cerebral vascular involvement
D57.818 …… with other specified complication
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.