2022 ICD-10-CM Diagnosis Code D57.8

Other sickle-cell disorders

    2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
  • D57.8 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2022 edition of ICD-10-CM D57.8 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of D57.8 - other international versions of ICD-10 D57.8 may differ.
Applicable To
  • Hb-SD disease
  • Hb-SE disease
The following code(s) above D57.8 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D57.8:
  • D50-D89
    2022 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D57
    ICD-10-CM Diagnosis Code D57

    Sickle-cell disorders

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • other hemoglobinopathies (D58.-)
    Use Additional
    • code for any associated fever (R50.81)
    Sickle-cell disorders
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
Code annotations containing back-references to D57.8:
  • Code First: N08
    ICD-10-CM Diagnosis Code N08

    Glomerular disorders in diseases classified elsewhere

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Manifestation Code
    Applicable To
    • Glomerulonephritis
    • Nephritis
    • Nephropathy
    Code First
    Type 1 Excludes
    • glomerulonephritis, nephritis and nephropathy (in):
    • antiglomerular basement membrane disease (M31.0)
    • diabetes (E08-E13 with .21)
    • gonococcal (A54.21)
    • Goodpasture's syndrome (M31.0)
    • hemolytic-uremic syndrome (D59.3)
    • lupus (M32.14)
    • mumps (B26.83)
    • syphilis (A52.75)
    • systemic lupus erythematosus (M32.14)
    • Wegener's granulomatosis (M31.31)
    • pyelonephritis in diseases classified elsewhere (N16)
    • renal tubulo-interstitial disorders classified elsewhere (N16)

Diagnosis Index entries containing back-references to D57.8:
  • Disease, diseased - see also Syndrome
    • hemoglobin or Hb
      • SD D57.8-
      • SE D57.8-
    • sickle-cell D57.1
      ICD-10-CM Diagnosis Code D57.1

      Sickle-cell disease without crisis

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      Applicable To
      • Hb-SS disease without crisis
      • Sickle-cell anemia NOS
      • Sickle-cell disease NOS
      • Sickle-cell disorder NOS
      • elliptocytosis D57.8-
  • Disorder (of) - see also Disease
  • Elliptocytosis (congenital) (hereditary) D58.1
    ICD-10-CM Diagnosis Code D58.1

    Hereditary elliptocytosis

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Elliptocytosis (congenital)
    • Ovalocytosis (congenital) (hereditary)
  • Spherocytosis (congenital) (familial) (hereditary) D58.0
    ICD-10-CM Diagnosis Code D58.0

    Hereditary spherocytosis

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Acholuric (familial) jaundice
    • Congenital (spherocytic) hemolytic icterus
    • Minkowski-Chauffard syndrome
    • sickle-cell D57.8- (disease)

ICD-10-CM Codes Adjacent To D57.8
D57.433 Sickle-cell thalassemia beta zero with cerebral vascular involvement
D57.438 …… with other specified complication
D57.439 …… unspecified
D57.44 …… beta plus without crisis
D57.45 Sickle-cell thalassemia beta plus with crisis
D57.451 Sickle-cell thalassemia beta plus with acute chest syndrome
D57.452 Sickle-cell thalassemia beta plus with splenic sequestration
D57.453 Sickle-cell thalassemia beta plus with cerebral vascular involvement
D57.458 …… with other specified complication
D57.459 …… unspecified
D57.8 Other sickle-cell disorders
D57.80 …… without crisis
D57.81 Other sickle-cell disorders with crisis
D57.811 Other sickle-cell disorders with acute chest syndrome
D57.812 Other sickle-cell disorders with splenic sequestration
D57.813 Other sickle-cell disorders with cerebral vascular involvement
D57.818 …… with other specified complication
D57.819 …… unspecified
D58 Other hereditary hemolytic anemias
D58.0 Hereditary spherocytosis
D58.1 Hereditary elliptocytosis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.