ICD-10-CM Codes
D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
D55-D59 Hemolytic anemias
D59- Acquired hemolytic anemia
2021 ICD-10-CM Diagnosis Code D59.1

2021 ICD-10-CM Diagnosis Code D59.1

Other autoimmune hemolytic anemias

2016

2017

2018

2019

2020

2021 - Deleted Code

Non-Billable/Non-Specific Code

D59.1 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
The 2021 edition of ICD-10-CM D59.1 became effective on October 1, 2020.
This is the American ICD-10-CM version of D59.1 - other international versions of ICD-10 D59.1 may differ.

Type 2 Excludes

Type 2 Excludes Help

A type 2 excludes note represents "not included here". A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. When a type 2 excludes note appears under a code it is acceptable to use both the code (D59.1) and the excluded code together.

Evans syndrome (
ICD-10-CM Diagnosis Code D69.41
Evans syndrome
D69.41
)
hemolytic disease of newborn (
ICD-10-CM Diagnosis Code P55
- P55 Hemolytic disease of newborn
  - P55.0 Rh isoimmunization of newborn
  - P55.1 ABO isoimmunization of newborn
  - P55.8 Other hemolytic diseases of newborn
  - P55.9 Hemolytic disease of newborn, unspecified
P55.-
)
paroxysmal cold hemoglobinuria (
ICD-10-CM Diagnosis Code D59.6
Hemoglobinuria due to hemolysis from other external causes
Applicable To
- Hemoglobinuria from exertion
- March hemoglobinuria
- Paroxysmal cold hemoglobinuria
Type 1 Excludes
- hemoglobinuria NOS (R82.3)
Use Additional
- code (Chapter 20) to identify external cause
D59.6
)

The following code(s) above D59.1 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to D59.1:

D50-D89
2021 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Type 2 Excludes
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Approximate Synonyms

Anemia, autoimmune hemolytic
Autoimmune hemolytic anemia
Chronic cold agglutinin disease
Cold agglutinin disease, chronic
Cold autoimmune hemolytic anemia
Drug-induced autoimmune hemolytic anemia
Hapten type high affinity hemolytic anemia
Hapten type low affinity hemolytic anemia
Hemolytic anemia associated with rheumatic disorder
Hemolytic anemia associated with systemic lupus erythematosus
Hemolytic anemia with systemic lupus erythematosus
Hemolytic anemia, cold antibody
Hemolytic anemia, drug induced autoimmune
Hemolytic anemia, due to warm antibody
Hemolytic anemia, high affinity hapten
Hemolytic anemia, low affinity hapten
Hemolytic anemia, rheumatic disease
Warm autoimmune hemolytic anemia

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): Deleted code

ICD-10-CM Codes Adjacent To D59.1

D57.818 …… with other specified complication

D57.819 …… unspecified

D58 Other hereditary hemolytic anemias

D58.0 Hereditary spherocytosis

D58.1 Hereditary elliptocytosis

D58.2 Other hemoglobinopathies

D58.8 Other specified hereditary hemolytic anemias

D58.9 Hereditary hemolytic anemia, unspecified

D59 Acquired hemolytic anemia

D59.0 Drug-induced autoimmune hemolytic anemia

D59.1 Other autoimmune hemolytic anemias

D59.10 Autoimmune hemolytic anemia, unspecified

D59.11 Warm autoimmune hemolytic anemia

D59.12 Cold autoimmune hemolytic anemia

D59.13 Mixed type autoimmune hemolytic anemia

D59.19 Other autoimmune hemolytic anemia

D59.2 Drug-induced nonautoimmune hemolytic anemia

D59.3 Hemolytic-uremic syndrome

D59.4 Other nonautoimmune hemolytic anemias

D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

D59.6 Hemoglobinuria due to hemolysis from other external causes

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2021 ICD-10-CM Diagnosis Code D59.1

Other autoimmune hemolytic anemias

Evans syndrome

Hemoglobinuria due to hemolysis from other external causes

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism