1. ICD-10-CM Codes
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2. D50-D89
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3. D55-D59
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4. D59-
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5. 2023 ICD-10-CM Diagnosis Code D59.3

2023 ICD-10-CM Diagnosis Code D59.3

Hemolytic-uremic syndrome

2016 2017 2018 2019 2020 2021 2022 2023 - Converted to Parent Code Non-Billable/Non-Specific Code

• D59.3 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
• ICD-10-CM D59.3 is a new 2023 ICD-10-CM code that became effective on October 1, 2022.
• This is the American ICD-10-CM version of D59.3 - other international versions of ICD-10 D59.3 may differ.

• Hemolytic uremic syndrome

• A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia.
• A form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia.
• A syndrome that is associated with microvascular diseases of the kidney, such as renal cortical necrosis. It is characterized by hemolytic anemia (anemia, hemolytic); thrombocytopenia; and acute renal failure.

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): Deleted code
• 2023 (effective 10/1/2022): New code

• Type 1 Excludes: N08
  , D69.1
  ICD-10-CM Diagnosis Code N08

  Glomerular disorders in diseases classified elsewhere

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Manifestation Code

  Applicable To

  • Glomerulonephritis
  • Nephritis
  • Nephropathy

  Code First

  • underlying disease, such as:
  • amyloidosis (E85.-)
  • congenital syphilis (A50.5)
  • cryoglobulinemia (D89.1)
  • disseminated intravascular coagulation (D65)
  • gout (M1A.-, M10.-)
  • microscopic polyangiitis (M31.7)
  • multiple myeloma (C90.0-)
  • sepsis (A40.0-A41.9)
  • sickle-cell disease (D57.0-D57.8)

  Type 1 Excludes

  • glomerulonephritis, nephritis and nephropathy (in):
  • antiglomerular basement membrane disease (M31.0)
  • diabetes (E08-E13 with .21)
  • gonococcal (A54.21)
  • Goodpasture's syndrome (M31.0)
  • hemolytic-uremic syndrome (D59.3-)
  • lupus (M32.14)
  • mumps (B26.83)
  • syphilis (A52.75)
  • systemic lupus erythematosus (M32.14)
  • Wegener's granulomatosis (M31.31)
  • pyelonephritis in diseases classified elsewhere (N16)
  • renal tubulo-interstitial disorders classified elsewhere (N16)
  ICD-10-CM Diagnosis Code D69.1

  Qualitative platelet defects

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Bernard-Soulier [giant platelet] syndrome
  • Glanzmann's disease
  • Grey platelet syndrome
  • Thromboasthenia (hemorrhagic) (hereditary)
  • Thrombocytopathy

  Type 1 Excludes

  • hemolytic-uremic syndrome (D59.3-)

  Type 2 Excludes

  • von Willebrand disease (D68.0-)
• Use Additional: M31.11
  ICD-10-CM Diagnosis Code M31.11

  Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

  2022 - New Code 2023 Billable/Specific Code

  Applicable To

  • Transplant-associated thrombotic microangiopathy [TA-TMA]

  Code First

  • if applicable:
  • complications of bone marrow transplant (T86.0-)
  • complications of stem cell transplant (T86.5)

  Use Additional

  • code to identify specific organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory distress syndrome (J80)
  • capillary leak syndrome (I78.8)
  • diffuse alveolar hemorrhage (R04.89)
  • encephalopathy (metabolic) (septic) (G93.41)
  • fluid overload, unspecified (E87.70)
  • graft versus host disease (D89.81-)
  • hemolytic uremic syndrome (D59.3-)
  • hepatic failure (K72.-)
  • hepatic veno-occlusive disease (K76.5)
  • idiopathic interstitial pneumonia (J84.11-)
  • sinusoidal obstruction syndrome (K76.5)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.