ICD-10-CM Codes
D50-D89
D55-D59
D59-
2023 ICD-10-CM Diagnosis Code D59.31

2023 ICD-10-CM Diagnosis Code D59.31

Infection-associated hemolytic-uremic syndrome

2023 - New Code

Billable/Specific Code

D59.31 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
ICD-10-CM D59.31 is a new 2023 ICD-10-CM code that became effective on October 1, 2022.
This is the American ICD-10-CM version of D59.31 - other international versions of ICD-10 D59.31 may differ.

Applicable To

Shiga toxin-producing E. coli [STEC] related hemolytic uremic syndrome
Typical hemolytic uremic syndrome

Use Additional

Use Additional Help

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.

code to identify associated infection, such as :
E. coli infection (
ICD-10-CM Diagnosis Code B96.2
Escherichia coli [E. coli ] as the cause of diseases classified elsewhere
B96.2-
)
Human immunodeficiency virus [HIV] disease (
ICD-10-CM Diagnosis Code B20
Human immunodeficiency virus [HIV] disease
Code First
- Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
Includes
- acquired immune deficiency syndrome [AIDS]
- AIDS-related complex [ARC]
- HIV infection, symptomatic
Type 1 Excludes
- asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
- exposure to HIV virus (Z20.6)
- inconclusive serologic evidence of HIV (R75)
Use Additional
- code(s) to identify all manifestations of HIV infection
B20
)
Pneumococcal meningitis (
ICD-10-CM Diagnosis Code G00.1
Pneumococcal meningitis
Applicable To
- Meningtitis due to Streptococcal pneumoniae
G00.1
)
Pneumococcal pneumonia (
ICD-10-CM Diagnosis Code J13
Pneumonia due to Streptococcus pneumoniae
Applicable To
- Bronchopneumonia due to S. pneumoniae
Code First
- associated influenza, if applicable (J09.X1, J10.0-, J11.0-)
Code Also
- associated abscess, if applicable (J85.1)
Type 1 Excludes
- congenital pneumonia due to S. pneumoniae (P23.6)
- lobar pneumonia, unspecified organism (J18.1)
- pneumonia due to other streptococci (J15.3-J15.4)
J13
)
Sepsis due to Streptococcus pneumoniae (
ICD-10-CM Diagnosis Code A40.3
Sepsis due to Streptococcus pneumoniae
Applicable To
- Pneumococcal sepsis
A40.3
)
Shigella dysenteriae (
ICD-10-CM Diagnosis Code A03.9
Shigellosis, unspecified
Applicable To
- Bacillary dysentery NOS
A03.9
)
Streptococcus pneumoniae as the cause of diseases classified elsewhere (
ICD-10-CM Diagnosis Code B95.3
Streptococcus pneumoniae as the cause of diseases classified elsewhere
B95.3
)

The following code(s) above D59.31 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to D59.31:

D50-D89
2023 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Type 2 Excludes
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
D59.3
ICD-10-CM Diagnosis Code D59.3
Hemolytic-uremic syndrome
Code Also
- , if applicable, any associated:
- acute kidney failure (N17.-)
- chronic kidney disease (N18.-)
Hemolytic-uremic syndrome

ICD-10-CM D59.31 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):

791 Prematurity with major problems
793 Full term neonate with major problems
811 Red blood cell disorders with mcc
812 Red blood cell disorders without mcc

Code History

2023 (effective 10/1/2022): New code

Diagnosis Index entries containing back-references to D59.31:

Syndrome - see also Disease
- hemolytic-uremic D59.30
  ICD-10-CM Diagnosis Code D59.30
  Hemolytic-uremic syndrome, unspecified
  2023 - New Code Billable/Specific Code
  Applicable To
  Hemolytic-uremic syndrome NOS
  - atypical D59.39
    ICD-10-CM Diagnosis Code D59.39
    Other hemolytic-uremic syndrome
    2023 - New Code Billable/Specific Code
    Applicable To
    Atypical (nongenetic) hemolytic uremic syndrome
    Secondary hemolytic-uremic syndrome
    Code First
    , if applicable, any associated:
    COVID-19 (U07.1)
    complications of kidney transplant (T86.1-)
    complications of heart transplant (T86.2-)
    complications of liver transplant (T86.4-)
    Code Also
    , if applicable, any associated condition, such as:
    hypertensive emergency (I16.1)
    malignant neoplasm (C00-C96)
    systemic lupus erythematosus (M32.-)
    Use Additional
    code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)
    - infection-associated D59.31
  - infection-associated D59.31
  - Shiga toxin-producing E. coli [STEC] related D59.31
  - typical D59.31

ICD-10-CM Codes Adjacent To D59.31

D59.0 Drug-induced autoimmune hemolytic anemia

D59.1 Other autoimmune hemolytic anemias

D59.10 Autoimmune hemolytic anemia, unspecified

D59.11 Warm autoimmune hemolytic anemia

D59.12 Cold autoimmune hemolytic anemia

D59.13 Mixed type autoimmune hemolytic anemia

D59.19 Other autoimmune hemolytic anemia

D59.2 Drug-induced nonautoimmune hemolytic anemia

D59.3 Hemolytic-uremic syndrome

D59.30 …… unspecified

D59.31 Infection-associated hemolytic-uremic syndrome

D59.32 Hereditary hemolytic-uremic syndrome

D59.39 Other hemolytic-uremic syndrome

D59.4 Other nonautoimmune hemolytic anemias

D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

D59.6 Hemoglobinuria due to hemolysis from other external causes

D59.8 Other acquired hemolytic anemias

D59.9 Acquired hemolytic anemia, unspecified

D60 Acquired pure red cell aplasia [erythroblastopenia]

D60.0 Chronic acquired pure red cell aplasia

D60.1 Transient acquired pure red cell aplasia

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code D59.31

Infection-associated hemolytic-uremic syndrome

Escherichia coli [E. coli ] as the cause of diseases classified elsewhere

Human immunodeficiency virus [HIV] disease

Pneumococcal meningitis

Pneumonia due to Streptococcus pneumoniae

Sepsis due to Streptococcus pneumoniae

Shigellosis, unspecified

Streptococcus pneumoniae as the cause of diseases classified elsewhere

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Hemolytic-uremic syndrome

Hemolytic-uremic syndrome, unspecified

Other hemolytic-uremic syndrome