2020 ICD-10-CM Diagnosis Code D59.6

Hemoglobinuria due to hemolysis from other external causes

    2016 2017 2018 2019 2020 Billable/Specific Code
  • D59.6 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM D59.6 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of D59.6 - other international versions of ICD-10 D59.6 may differ.
Applicable To
  • Hemoglobinuria from exertion
  • March hemoglobinuria
  • Paroxysmal cold hemoglobinuria
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code (Chapter 20) to identify external cause
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D59.6. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • hemoglobinuria NOS (
    ICD-10-CM Diagnosis Code R82.3

    Hemoglobinuria

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • hemoglobinuria due to hemolysis from external causes NEC (D59.6)
    • hemoglobinuria due to paroxysmal nocturnal [Marchiafava-Micheli] (D59.5)
    R82.3
    )
The following code(s) above D59.6 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D59.6:
  • D50-D89
    2020 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Approximate Synonyms
  • Hemoglobinuria - external causation
  • Hemoglobinuria, extrinsic
ICD-10-CM D59.6 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems
  • 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
  • 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
  • 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc

Convert D59.6 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to D59.6:
  • Type 1 Excludes: D59.1
    , R82.3
    ICD-10-CM Diagnosis Code D59.1

    Other autoimmune hemolytic anemias

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Autoimmune hemolytic disease (cold type) (warm type)
    • Chronic cold hemagglutinin disease
    • Cold agglutinin disease
    • Cold agglutinin hemoglobinuria
    • Cold type (secondary) (symptomatic) hemolytic anemia
    • Warm type (secondary) (symptomatic) hemolytic anemia
    Type 1 Excludes
    • Evans syndrome (D69.41)
    • hemolytic disease of newborn (P55.-)
    • paroxysmal cold hemoglobinuria (D59.6)
    ICD-10-CM Diagnosis Code R82.3

    Hemoglobinuria

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • hemoglobinuria due to hemolysis from external causes NEC (D59.6)
    • hemoglobinuria due to paroxysmal nocturnal [Marchiafava-Micheli] (D59.5)

Diagnosis Index entries containing back-references to D59.6:
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
    ICD-10-CM Diagnosis Code D64.9

    Anemia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • hemolytic D58.9
      ICD-10-CM Diagnosis Code D58.9

      Hereditary hemolytic anemia, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
      • acquired D59.9
        ICD-10-CM Diagnosis Code D59.9

        Acquired hemolytic anemia, unspecified

          2016 2017 2018 2019 2020 Billable/Specific Code
        Applicable To
        • Idiopathic hemolytic anemia, chronic
        • with hemoglobinuria NEC D59.6
  • Disease, diseased - see also Syndrome
    • cold
      • agglutinin or hemoglobinuria D59.1
        ICD-10-CM Diagnosis Code D59.1

        Other autoimmune hemolytic anemias

          2016 2017 2018 2019 2020 Billable/Specific Code
        Applicable To
        • Autoimmune hemolytic disease (cold type) (warm type)
        • Chronic cold hemagglutinin disease
        • Cold agglutinin disease
        • Cold agglutinin hemoglobinuria
        • Cold type (secondary) (symptomatic) hemolytic anemia
        • Warm type (secondary) (symptomatic) hemolytic anemia
        Type 1 Excludes
        • Evans syndrome (D69.41)
        • hemolytic disease of newborn (P55.-)
        • paroxysmal cold hemoglobinuria (D59.6)
        • paroxysmal D59.6
  • Harley's disease D59.6
  • Hemoglobinemia D59.9
    ICD-10-CM Diagnosis Code D59.9

    Acquired hemolytic anemia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Idiopathic hemolytic anemia, chronic
  • Hemoglobinuria R82.3
    ICD-10-CM Diagnosis Code R82.3

    Hemoglobinuria

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • hemoglobinuria due to hemolysis from external causes NEC (D59.6)
    • hemoglobinuria due to paroxysmal nocturnal [Marchiafava-Micheli] (D59.5)
    • paroxysmal (cold) D59.6
    • with anemia, hemolytic, acquired D59.6 (chronic)
    • cold D59.6 (agglutinin) (paroxysmal) (with Raynaud's syndrome)
    • due to exertion or hemolysis NEC D59.6
    • intermittent D59.6
    • march D59.6
  • March
    • hemoglobinuria D59.6
  • Murri's disease D59.6 (intermittent hemoglobinuria)

ICD-10-CM Codes Adjacent To D59.6
D58.2 Other hemoglobinopathies
D58.8 Other specified hereditary hemolytic anemias
D58.9 Hereditary hemolytic anemia, unspecified
D59 Acquired hemolytic anemia
D59.0 Drug-induced autoimmune hemolytic anemia
D59.1 Other autoimmune hemolytic anemias
D59.2 Drug-induced nonautoimmune hemolytic anemia
D59.3 Hemolytic-uremic syndrome
D59.4 Other nonautoimmune hemolytic anemias
D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
D59.6 Hemoglobinuria due to hemolysis from other external causes
D59.8 Other acquired hemolytic anemias
D59.9 Acquired hemolytic anemia, unspecified
D60 Acquired pure red cell aplasia [erythroblastopenia]
D60.0 Chronic acquired pure red cell aplasia
D60.1 Transient acquired pure red cell aplasia
D60.8 Other acquired pure red cell aplasias
D60.9 Acquired pure red cell aplasia, unspecified
D61 Other aplastic anemias and other bone marrow failure syndromes
D61.0 Constitutional aplastic anemia
D61.01 Constitutional (pure) red blood cell aplasia

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.