2019 ICD-10-CM Diagnosis Code D61.01

Constitutional (pure) red blood cell aplasia

    2016 2017 2018 2019 Billable/Specific Code
  • D61.01 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM D61.01 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of D61.01 - other international versions of ICD-10 D61.01 may differ.
Applicable To
  • Blackfan-Diamond syndrome
  • Congenital (pure) red cell aplasia
  • Familial hypoplastic anemia
  • Primary (pure) red cell aplasia
  • Red cell (pure) aplasia of infants
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D61.01. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • acquired red cell aplasia (
    ICD-10-CM Diagnosis Code D60.9

    Acquired pure red cell aplasia, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    D60.9
    )
The following code(s) above D61.01 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D61.01:
  • D50-D89
    2019 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D61
    ICD-10-CM Diagnosis Code D61

    Other aplastic anemias and other bone marrow failure syndromes

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    Other aplastic anemias and other bone marrow failure syndromes
Approximate Synonyms
  • Anemia, blackfan-diamond
  • Constitutional red blood cell aplasia
  • Constitutional red cell aplasia
  • Diamond-blackfan anemia
  • Pure red cell aplasia
Clinical Information
  • A rare congenital hypoplastic anemia that usually presents early in infancy. The disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (curr opin hematol 2000 mar;7(2):85-94)
  • A very rare disorder in which the bone marrow doesn't make enough red blood cells. It is usually seen in the first year of life. Patients may have deformed thumbs and other physical problems. They also have an increased risk of leukemia and sarcoma, especially osteosarcoma (bone cancer). Patients with congenital pure red cell aplasia may have a mutation (change) in one of the genes that make proteins found in the cell's ribosomes.
  • An inborn condition characterized by deficiencies of red cell precursors that sometimes also includes leukopenia and thrombocytopenia.
  • An inherited condition characterized by aplasia of the erythroid series only. The white cells and platelets are not affected. Patients develop anemia usually in infancy.
ICD-10-CM D61.01 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
  • 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
  • 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc

Convert D61.01 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to D61.01:
  • Type 1 Excludes: D60
    , D61.81
    , D64.4
    ICD-10-CM Diagnosis Code D60

    Acquired pure red cell aplasia [erythroblastopenia]

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Includes
    • red cell aplasia (acquired) (adult) (with thymoma)
    Type 1 Excludes
    • congenital red cell aplasia (D61.01)
    ICD-10-CM Diagnosis Code D61.81

    Pancytopenia

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • pancytopenia (due to) (with) aplastic anemia (D61.9)
    • pancytopenia (due to) (with) bone marrow infiltration (D61.82)
    • pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
    • pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
    • pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
    • pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
    • pancytopenia (due to) (with) myeloproliferative disease (D47.1)
    Type 2 Excludes
    • pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)
    ICD-10-CM Diagnosis Code D64.4

    Congenital dyserythropoietic anemia

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Dyshematopoietic anemia (congenital)
    Type 1 Excludes
    • Blackfan-Diamond syndrome (D61.01)
    • Di Guglielmo's disease (C94.0)

Diagnosis Index entries containing back-references to D61.01:
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
    ICD-10-CM Diagnosis Code D64.9

    Anemia, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    • aplastic D61.9
      ICD-10-CM Diagnosis Code D61.9

      Aplastic anemia, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      Applicable To
      • Hypoplastic anemia NOS
      • Medullary hypoplasia
      • red cell (pure) D60.9
        ICD-10-CM Diagnosis Code D60.9

        Acquired pure red cell aplasia, unspecified

          2016 2017 2018 2019 Billable/Specific Code
        • congenital D61.01
    • hypoplasia, red blood cells D61.9
      ICD-10-CM Diagnosis Code D61.9

      Aplastic anemia, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      Applicable To
      • Hypoplastic anemia NOS
      • Medullary hypoplasia
      • congenital or familial D61.01
    • hypoplastic (idiopathic) D61.9
      ICD-10-CM Diagnosis Code D61.9

      Aplastic anemia, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      Applicable To
      • Hypoplastic anemia NOS
      • Medullary hypoplasia
      • congenital or familial D61.01 (of childhood)
    • pure red cell D60.9
      ICD-10-CM Diagnosis Code D60.9

      Acquired pure red cell aplasia, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      • congenital D61.01
    • Diamond-Blackfan D61.01 (congenital hypoplastic)
    • Joseph-Diamond-Blackfan D61.01 (congenital hypoplastic)
  • Aplasia - see also Agenesis
    • bone marrow (myeloid) D61.9
      ICD-10-CM Diagnosis Code D61.9

      Aplastic anemia, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      Applicable To
      • Hypoplastic anemia NOS
      • Medullary hypoplasia
      • congenital D61.01
    • red cell (with thymoma) D60.9
      ICD-10-CM Diagnosis Code D60.9

      Acquired pure red cell aplasia, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      • pure D61.01
      • congenital D61.01
      • constitutional D61.01
      • hereditary D61.01
      • of infants D61.01
      • primary D61.01
    • congenital pure red cell D61.01
    • erythrocyte congenital D61.01
  • Blackfan-Diamond anemia or syndrome D61.01 (congenital hypoplastic anemia)
  • Diamond-Blackfan anemia D61.01 (congenital hypoplastic)
  • Erythroblastopenia D60.9
    - see also Aplasia, red cell
    ICD-10-CM Diagnosis Code D60.9

    Acquired pure red cell aplasia, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    • congenital D61.01
  • Hypoplasia, hypoplastic
    • erythroid, congenital D61.01
  • Joseph-Diamond-Blackfan anemia D61.01 (congenital hypoplastic)
  • Kaznelson's syndrome D61.01 (congenital hypoplastic anemia)
  • Syndrome - see also Disease
    • Blackfan-Diamond D61.01
    • Diamond-Blackfan D61.01
    • Joseph-Diamond-Blackfan D61.01

ICD-10-CM Codes Adjacent To D61.01
D59.6 Hemoglobinuria due to hemolysis from other external causes
D59.8 Other acquired hemolytic anemias
D59.9 Acquired hemolytic anemia, unspecified
D60 Acquired pure red cell aplasia [erythroblastopenia]
D60.0 Chronic acquired pure red cell aplasia
D60.1 Transient acquired pure red cell aplasia
D60.8 Other acquired pure red cell aplasias
D60.9 Acquired pure red cell aplasia, unspecified
D61 Other aplastic anemias and other bone marrow failure syndromes
D61.0 Constitutional aplastic anemia
D61.01 Constitutional (pure) red blood cell aplasia
D61.09 Other constitutional aplastic anemia
D61.1 Drug-induced aplastic anemia
D61.2 Aplastic anemia due to other external agents
D61.3 Idiopathic aplastic anemia
D61.8 Other specified aplastic anemias and other bone marrow failure syndromes
D61.81 Pancytopenia
D61.810 Antineoplastic chemotherapy induced pancytopenia
D61.811 Other drug-induced pancytopenia
D61.818 Other pancytopenia
D61.82 Myelophthisis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.