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ICD-10-CM Codes
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D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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D60-D64
Aplastic and other anemias and other bone marrow failure syndromes
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D61-
Other aplastic anemias and other bone marrow failure syndromes
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2018 ICD-10-CM Diagnosis Code D61.1
Drug-induced aplastic anemia
2016 2017 2018 Billable/Specific Code
- D61.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2018 edition of ICD-10-CM D61.1 became effective on October 1, 2017.
- This is the American ICD-10-CM version of D61.1 - other international versions of ICD-10 D61.1 may differ.
Use AdditionalUse Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
- code for adverse effect, if applicable, to identify drug (T36-T50
ICD-10-CM Range T36-T50
Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substancesCode First- , for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS (T88.7 )
- aspirin gastritis (K29.-)
- blood disorders (D56-D76 )
- contact dermatitis (L23-L25 )
- dermatitis due to substances taken internally (L27.-)
- nephropathy (N14.0-N14.2)
Includes- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Note- The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
Type 1 Excludes- toxic reaction to local anesthesia in pregnancy (O29.3-)
Type 2 Excludes- abuse and dependence of psychoactive substances (F10-F19)
- abuse of non-dependence-producing substances (F55.-)
- drug reaction and poisoning affecting newborn (P00-P96)
- pathological drug intoxication (inebriation) (F10-F19)
Use Additional- code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
- T36 Poisoning by, adverse effect of and unde...
- T37 Poisoning by, adverse effect of and unde...
- T38 Poisoning by, adverse effect of and unde...
- T39 Poisoning by, adverse effect of and unde...
- T40 Poisoning by, adverse effect of and unde...
- T41 Poisoning by, adverse effect of and unde...
- T42 Poisoning by, adverse effect of and unde...
- T43 Poisoning by, adverse effect of and unde...
- T44 Poisoning by, adverse effect of and unde...
- T45 Poisoning by, adverse effect of and unde...
- T46 Poisoning by, adverse effect of and unde...
- T47 Poisoning by, adverse effect of and unde...
- T48 Poisoning by, adverse effect of and unde...
- T49 Poisoning by, adverse effect of and unde...
- T50 Poisoning by, adverse effect of and unde...
The following code(s) above
D61.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D61.1:
- Anemia, drug induced aplastic
- Aplastic anemia due to chemotherapy
- Aplastic anemia due to drugs
Clinical Information
- A state of bone marrow suppression and failure that is caused by a cytotoxic or adverse immunologic response to a drug treatment, leading to a failure of production of red blood cells, white cells and platelets.
ICD-10-CM D61.1 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):
- 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
- 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
- 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc
Convert D61.1 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
Code annotations containing back-references to D61.1:
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Type 1 Excludes: D63.0, D64.81
ICD-10-CM Diagnosis Code D63.0
Anemia in neoplastic disease
2016 2017 2018 Billable/Specific Code Manifestation Code
Type 1 Excludes- aplastic anemia due to antineoplastic chemotherapy (D61.1)
Type 2 Excludes- anemia due to antineoplastic chemotherapy (D64.81)
ICD-10-CM Diagnosis Code D64.81
Anemia due to antineoplastic chemotherapy
2016 2017 2018 Billable/Specific Code
Applicable To- Antineoplastic chemotherapy induced anemia
Type 1 Excludes- aplastic anemia due to antineoplastic chemotherapy (D61.1)
Type 2 Excludes- anemia in neoplastic disease (D63.0)
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Type 2 Excludes: D46, D61.810, D61.811
ICD-10-CM Diagnosis Code D46
Myelodysplastic syndromes
2016 2017 2018 Non-Billable/Non-Specific Code
Type 2 Excludes- drug-induced aplastic anemia (D61.1)
Use Additional- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
ICD-10-CM Diagnosis Code D61.810
Antineoplastic chemotherapy induced pancytopenia
2016 2017 2018 Billable/Specific Code
Type 2 Excludes- aplastic anemia due to antineoplastic chemotherapy (D61.1)
ICD-10-CM Diagnosis Code D61.811
Other drug-induced pancytopenia
2016 2017 2018 Billable/Specific Code
Type 2 Excludes- aplastic anemia due to drugs (D61.1)
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
ICD-10-CM Diagnosis Code D64.9
Anemia, unspecified
2016 2017 2018 Billable/Specific Code
- aplastic D61.9
ICD-10-CM Diagnosis Code D61.9
Aplastic anemia, unspecified
2016 2017 2018 Billable/Specific Code
Applicable To- Hypoplastic anemia NOS
- Medullary hypoplasia
ICD-10-CM Codes Adjacent To D61.1
D59.9 Acquired hemolytic anemia, unspecified
D60 Acquired pure red cell aplasia [erythroblastopenia]
D60.0 Chronic acquired pure red cell aplasia
D60.1 Transient acquired pure red cell aplasia
D60.8 Other acquired pure red cell aplasias
D60.9 Acquired pure red cell aplasia, unspecified
D61 Other aplastic anemias and other bone marrow failure syndromes
D61.0 Constitutional aplastic anemia
D61.01 Constitutional (pure) red blood cell aplasia
D61.09 Other constitutional aplastic anemia
D61.1
Drug-induced aplastic anemia
D61.2 Aplastic anemia due to other external agents
D61.3 Idiopathic aplastic anemia
D61.8 Other specified aplastic anemias and other bone marrow failure syndromes
D61.810 Antineoplastic chemotherapy induced pancytopenia
D61.811 Other drug-induced pancytopenia
D61.89 Other specified aplastic anemias and other bone marrow failure syndromes
D61.9 Aplastic anemia, unspecified
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
