2023 ICD-10-CM Diagnosis Code D65

Disseminated intravascular coagulation [defibrination syndrome]

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • D65 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Disseminated intravascular coagulation
  • The 2023 edition of ICD-10-CM D65 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of D65 - other international versions of ICD-10 D65 may differ.
Applicable To
  • Afibrinogenemia, acquired
  • Consumption coagulopathy
  • Diffuse or disseminated intravascular coagulation [DIC]
  • Fibrinolytic hemorrhage, acquired
  • Fibrinolytic purpura
  • Purpura fulminans
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D65. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • disseminated intravascular coagulation (complicating):
  • abortion or ectopic or molar pregnancy (
    ICD-10-CM Diagnosis Code O00

    Ectopic pregnancy

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Includes
    • ruptured ectopic pregnancy
    Use Additional
    • code from category O08 to identify any associated complication
    O00
    -
    ICD-10-CM Diagnosis Code O07

    Failed attempted termination of pregnancy

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Includes
    • failure of attempted induction of termination of pregnancy
    • incomplete elective abortion
    Type 1 Excludes
    • incomplete spontaneous abortion (O03.0-)
    O07
    ,
    ICD-10-CM Diagnosis Code O08.1

    Delayed or excessive hemorrhage following ectopic and molar pregnancy

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Applicable To
    • Afibrinogenemia following ectopic and molar pregnancy
    • Defibrination syndrome following ectopic and molar pregnancy
    • Hemolysis following ectopic and molar pregnancy
    • Intravascular coagulation following ectopic and molar pregnancy
    Type 1 Excludes
    • delayed or excessive hemorrhage due to incomplete abortion (O03.1)
    O08.1
    )
  • in newborn (
    ICD-10-CM Diagnosis Code P60

    Disseminated intravascular coagulation of newborn

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Code on Newborn Record
    Applicable To
    • Defibrination syndrome of newborn
    P60
    )
  • pregnancy, childbirth and the puerperium (
    ICD-10-CM Diagnosis Code O45.0

    Premature separation of placenta with coagulation defect

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    O45.0
    ,
    ICD-10-CM Diagnosis Code O46.0

    Antepartum hemorrhage with coagulation defect

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    O46.0
    ,
    ICD-10-CM Diagnosis Code O67.0

    Intrapartum hemorrhage with coagulation defect

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Applicable To
    • Intrapartum hemorrhage (excessive) associated with afibrinogenemia
    • Intrapartum hemorrhage (excessive) associated with disseminated intravascular coagulation
    • Intrapartum hemorrhage (excessive) associated with hyperfibrinolysis
    • Intrapartum hemorrhage (excessive) associated with hypofibrinogenemia
    O67.0
    ,
    ICD-10-CM Diagnosis Code O72.3

    Postpartum coagulation defects

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Maternity Dx (12-55 years) Female Dx
    Applicable To
    • Postpartum afibrinogenemia
    • Postpartum fibrinolysis
    O72.3
    )
The following code(s) above D65 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D65:
  • D50-D89
    2023 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Approximate Synonyms
  • Disseminated intravascular coagulation
  • Purpura fulminans
Clinical Information
  • A disease where the blood clots throughout the body and increases the risk of bleeding
  • A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to purpura fulminans.
  • A disorder characterized by reduction in the elements involved in blood coagulation due to their utilization in widespread blood clotting within the vessels.
  • A disorder characterized by systemic pathological activation of blood clotting mechanisms which results in clot formation throughout the body. There is an increase in the risk of hemorrhage as the body is depleted of platelets and coagulation factors.
  • A pathological process in the body where the blood starts to coagulate throughout the whole body. This depletes the body of its platelets and coagulation factors, and there is an increased the risk of hemorrhage.
  • A pathological process where the blood starts to coagulate throughout the whole body. This depletes the body of its platelets and coagulation factors, and there is an increased risk of hemorrhage.
  • A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by disseminated intravascular coagulation.
  • Disorder characterized by reduction in the elements involved in blood coagulation due to their utilization in widespread blood clotting within the vessels; the activation of the clotting mechanism may arise from any of a number of disorders; in the late stages, it is marked by profuse hemorrhaging.
ICD-10-CM D65 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems
  • 813 Coagulation disorders

Convert D65 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to D65:
  • Code First: N08
    ICD-10-CM Diagnosis Code N08

    Glomerular disorders in diseases classified elsewhere

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Manifestation Code
    Applicable To
    • Glomerulonephritis
    • Nephritis
    • Nephropathy
    Code First
    Type 1 Excludes
    • glomerulonephritis, nephritis and nephropathy (in):
    • antiglomerular basement membrane disease (M31.0)
    • diabetes (E08-E13 with .21)
    • gonococcal (A54.21)
    • Goodpasture's syndrome (M31.0)
    • hemolytic-uremic syndrome (D59.3-)
    • lupus (M32.14)
    • mumps (B26.83)
    • syphilis (A52.75)
    • systemic lupus erythematosus (M32.14)
    • Wegener's granulomatosis (M31.31)
    • pyelonephritis in diseases classified elsewhere (N16)
    • renal tubulo-interstitial disorders classified elsewhere (N16)
  • Type 1 Excludes: D68.6
    , D69
    ICD-10-CM Diagnosis Code D68.6

    Other thrombophilia

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Applicable To
    • Other hypercoagulable states
    Type 1 Excludes
    • diffuse or disseminated intravascular coagulation [DIC] (D65)
    • heparin induced thrombocytopenia (HIT) (D75.82-)
    • hyperhomocysteinemia (E72.11)
    ICD-10-CM Diagnosis Code D69

    Purpura and other hemorrhagic conditions

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • benign hypergammaglobulinemic purpura (D89.0)
    • cryoglobulinemic purpura (D89.1)
    • essential (hemorrhagic) thrombocythemia (D47.3)
    • hemorrhagic thrombocythemia (D47.3)
    • purpura fulminans (D65)
    • thrombotic thrombocytopenic purpura (M31.19)
    • Waldenström hypergammaglobulinemic purpura (D89.0)
  • Use Additional: R65.11
    , R65.2
    ICD-10-CM Diagnosis Code R65.11

    Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Use Additional
    • code to identify specific acute organ dysfunction, such as:
    • acute kidney failure (N17.-)
    • acute respiratory failure (J96.0-)
    • critical illness myopathy (G72.81)
    • critical illness polyneuropathy (G62.81)
    • disseminated intravascular coagulopathy [DIC] (D65)
    • encephalopathy (metabolic) (septic) (G93.41)
    • hepatic failure (K72.0-)
    ICD-10-CM Diagnosis Code R65.2

    Severe sepsis

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Applicable To
    • Infection with associated acute organ dysfunction
    • Sepsis with acute organ dysfunction
    • Sepsis with multiple organ dysfunction
    • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
    Code First
    • underlying infection, such as:
    • infection following a procedure (T81.4-)
    • infections following infusion, transfusion and therapeutic injection (T80.2-)
    • puerperal sepsis (O85)
    • sepsis following complete or unspecified spontaneous abortion (O03.87)
    • sepsis following ectopic and molar pregnancy (O08.82)
    • sepsis following incomplete spontaneous abortion (O03.37)
    • sepsis following (induced) termination of pregnancy (O04.87)
    • sepsis NOS (A41.9)
    Use Additional
    • code to identify specific acute organ dysfunction, such as:
    • acute kidney failure (N17.-)
    • acute respiratory failure (J96.0-)
    • critical illness myopathy (G72.81)
    • critical illness polyneuropathy (G62.81)
    • disseminated intravascular coagulopathy [DIC] (D65)
    • encephalopathy (metabolic) (septic) (G93.41)
    • hepatic failure (K72.0-)

Diagnosis Index entries containing back-references to D65:
  • Absence (of) (organ or part) (complete or partial)
    • fibrinogen (congenital) D68.2
      ICD-10-CM Diagnosis Code D68.2

      Hereditary deficiency of other clotting factors

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • AC globulin deficiency
      • Congenital afibrinogenemia
      • Deficiency of factor I [fibrinogen]
      • Deficiency of factor II [prothrombin]
      • Deficiency of factor V [labile]
      • Deficiency of factor VII [stable]
      • Deficiency of factor X [Stuart-Prower]
      • Deficiency of factor XII [Hageman]
      • Deficiency of factor XIII [fibrin stabilizing]
      • Dysfibrinogenemia (congenital)
      • Hypoproconvertinemia
      • Owren's disease
      • Proaccelerin deficiency
      • acquired D65
  • Afibrinogenemia D68.8
    - see also Defect, coagulation
    ICD-10-CM Diagnosis Code D68.8

    Other specified coagulation defects

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • hemorrhagic disease of newborn (P53)
    • acquired D65
  • Coagulopathy - see also Defect, coagulation
  • Defibrination (syndrome) D65
  • Deficiency, deficient
    • fibrinogen (congenital) (hereditary) D68.2
      ICD-10-CM Diagnosis Code D68.2

      Hereditary deficiency of other clotting factors

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • AC globulin deficiency
      • Congenital afibrinogenemia
      • Deficiency of factor I [fibrinogen]
      • Deficiency of factor II [prothrombin]
      • Deficiency of factor V [labile]
      • Deficiency of factor VII [stable]
      • Deficiency of factor X [Stuart-Prower]
      • Deficiency of factor XII [Hageman]
      • Deficiency of factor XIII [fibrin stabilizing]
      • Dysfibrinogenemia (congenital)
      • Hypoproconvertinemia
      • Owren's disease
      • Proaccelerin deficiency
      • acquired D65
  • Disorder (of) - see also Disease
    • glomerular (in) N05.9
      ICD-10-CM Diagnosis Code N05.9

      Unspecified nephritic syndrome with unspecified morphologic changes

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      • disseminated intravascular coagulation D65
  • Fibrinogenopenia D68.8
    ICD-10-CM Diagnosis Code D68.8

    Other specified coagulation defects

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • hemorrhagic disease of newborn (P53)
    • acquired D65
  • Fibrinolysis (hemorrhagic) (acquired) D65
  • Glomerulonephritis N05.9
    - see also Nephritis
    ICD-10-CM Diagnosis Code N05.9

    Unspecified nephritic syndrome with unspecified morphologic changes

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    • in (due to)
      • defibrination syndrome D65
      • disseminated intravascular coagulation D65
  • Hypofibrinogenemia D68.8
    ICD-10-CM Diagnosis Code D68.8

    Other specified coagulation defects

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • hemorrhagic disease of newborn (P53)
    • acquired D65
  • Proteolysis, pathologic D65
  • Purpura D69.2
    ICD-10-CM Diagnosis Code D69.2

    Other nonthrombocytopenic purpura

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Purpura NOS
    • Purpura simplex
    • Senile purpura
    • fulminans, fulminous D65
    • gangrenous D65
  • Syndrome - see also Disease
    • DIC D65 (diffuse or disseminated intravascular coagulopathy)
    • ICF D65 (intravascular coagulation-fibrinolysis)
    • intravascular coagulation-fibrinolysis D65 (ICF)
    • IVC D65 (intravascular coagulopathy)

ICD-10-CM Codes Adjacent To D65
D64 Other anemias
D64.0 Hereditary sideroblastic anemia
D64.1 Secondary sideroblastic anemia due to disease
D64.2 Secondary sideroblastic anemia due to drugs and toxins
D64.3 Other sideroblastic anemias
D64.4 Congenital dyserythropoietic anemia
D64.8 Other specified anemias
D64.81 Anemia due to antineoplastic chemotherapy
D64.89 Other specified anemias
D64.9 Anemia, unspecified
D65 Disseminated intravascular coagulation [defibrination syndrome]
D66 Hereditary factor VIII deficiency
D67 Hereditary factor IX deficiency
D68 Other coagulation defects
D68.0 Von Willebrand disease
D68.00 …… unspecified
D68.01 …… type 1
D68.02 Von Willebrand disease, type 2
D68.020 ……A
D68.021 ……B
D68.022 ……M

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.