2019 ICD-10-CM Diagnosis Code D66

Hereditary factor VIII deficiency

    2016 2017 2018 2019 Billable/Specific Code
  • D66 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM D66 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of D66 - other international versions of ICD-10 D66 may differ.
Applicable To
  • Classical hemophilia
  • Deficiency factor VIII (with functional defect)
  • Hemophilia NOS
  • Hemophilia A
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D66. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • factor VIII deficiency with vascular defect (
    ICD-10-CM Diagnosis Code D68.0

    Von Willebrand's disease

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Angiohemophilia
    • Factor VIII deficiency with vascular defect
    • Vascular hemophilia
    Type 1 Excludes
    • capillary fragility (hereditary) (D69.8)
    • factor VIII deficiency NOS (D66)
    • factor VIII deficiency with functional defect (D66)
    D68.0
    )
The following code(s) above D66 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D66:
  • D50-D89
    2019 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Approximate Synonyms
  • Hemophilia
  • Hemophilia a
  • Hemophilic arthritis
  • Hemophilic arthropathy
  • Hereditary factor viii deficiency disease
Clinical Information
  • An inherited deficiency of coagulation factor viii characterized by the tendency to spontaneous or exaggerated post-traumatic hemorrhage. Inherited as an x-linked recessive disease, hemophilia a is the most common hemophilia, occurring in approximately 1 in 10,000 male births.
  • Classic hemophilia resulting from a deficiency of factor viii; an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.
  • The classic hemophilia resulting from a deficiency of factor viii. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.
ICD-10-CM D66 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 813 Coagulation disorders

Convert D66 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to D66:
  • Code First: M36.2
    , M36.2
    ICD-10-CM Diagnosis Code M36.2

    Hemophilic arthropathy

      2016 2017 2018 2019 Billable/Specific Code Manifestation Code
    Applicable To
    • Hemarthrosis in hemophilic arthropathy
    Code First
    • underlying disease, such as:
    • factor VIII deficiency (D66)
    • with vascular defect (D68.0)
    • factor IX deficiency (D67)
    • hemophilia (classical) (D66)
    • hemophilia B (D67)
    • hemophilia C (D68.1)
    ICD-10-CM Diagnosis Code M36.2

    Hemophilic arthropathy

      2016 2017 2018 2019 Billable/Specific Code Manifestation Code
    Applicable To
    • Hemarthrosis in hemophilic arthropathy
    Code First
    • underlying disease, such as:
    • factor VIII deficiency (D66)
    • with vascular defect (D68.0)
    • factor IX deficiency (D67)
    • hemophilia (classical) (D66)
    • hemophilia B (D67)
    • hemophilia C (D68.1)
  • Type 1 Excludes: D68.0
    , D68.0
    ICD-10-CM Diagnosis Code D68.0

    Von Willebrand's disease

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Angiohemophilia
    • Factor VIII deficiency with vascular defect
    • Vascular hemophilia
    Type 1 Excludes
    • capillary fragility (hereditary) (D69.8)
    • factor VIII deficiency NOS (D66)
    • factor VIII deficiency with functional defect (D66)
    ICD-10-CM Diagnosis Code D68.0

    Von Willebrand's disease

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Angiohemophilia
    • Factor VIII deficiency with vascular defect
    • Vascular hemophilia
    Type 1 Excludes
    • capillary fragility (hereditary) (D69.8)
    • factor VIII deficiency NOS (D66)
    • factor VIII deficiency with functional defect (D66)

Diagnosis Index entries containing back-references to D66:

ICD-10-CM Codes Adjacent To D66
D64.0 Hereditary sideroblastic anemia
D64.1 Secondary sideroblastic anemia due to disease
D64.2 Secondary sideroblastic anemia due to drugs and toxins
D64.3 Other sideroblastic anemias
D64.4 Congenital dyserythropoietic anemia
D64.8 Other specified anemias
D64.81 Anemia due to antineoplastic chemotherapy
D64.89 Other specified anemias
D64.9 Anemia, unspecified
D65 Disseminated intravascular coagulation [defibrination syndrome]
D66 Hereditary factor VIII deficiency
D67 Hereditary factor IX deficiency
D68 Other coagulation defects
D68.0 Von Willebrand's disease
D68.1 Hereditary factor XI deficiency
D68.2 Hereditary deficiency of other clotting factors
D68.3 Hemorrhagic disorder due to circulating anticoagulants
D68.31 Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
D68.311 Acquired hemophilia
D68.312 Antiphospholipid antibody with hemorrhagic disorder
D68.318 Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.