2020 ICD-10-CM Diagnosis Code D70.1

Agranulocytosis secondary to cancer chemotherapy

    2016 2017 2018 2019 2020 Billable/Specific Code
  • D70.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM D70.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of D70.1 - other international versions of ICD-10 D70.1 may differ.
Use Additional
Use Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
  • code for adverse effect, if applicable, to identify drug (
    ICD-10-CM Diagnosis Code T45.1X5

    Adverse effect of antineoplastic and immunosuppressive drugs

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    T45.1X5
    )
Code Also
Code Also Help
A code also note instructs that 2 codes may be required to fully describe a condition but the sequencing of the two codes is discretionary, depending on the severity of the conditions and the reason for the encounter.
  • underlying neoplasm
The following code(s) above D70.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D70.1:
  • D50-D89
    2020 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D70
    ICD-10-CM Diagnosis Code D70

    Neutropenia

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Includes
    • agranulocytosis
    • decreased absolute neurophile count (ANC)
    Type 1 Excludes
    • neutropenic splenomegaly (D73.81)
    • transient neonatal neutropenia (P61.5)
    Use Additional
    Neutropenia
Approximate Synonyms
  • Agranulocytosis due to cancer chemotherapy
  • Chemotherapy-induced neutropenia
  • Neutropenia due to chemotherapy
ICD-10-CM D70.1 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
  • 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
  • 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc

Convert D70.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to D70.1:
  • Agranulocytosis (chronic) (cyclical) (genetic) (infantile) (periodic) (pernicious) D70.9
    - see also Neutropenia
    ICD-10-CM Diagnosis Code D70.9

    Neutropenia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • drug-induced D70.2
      ICD-10-CM Diagnosis Code D70.2

      Other drug-induced agranulocytosis

        2016 2017 2018 2019 2020 Billable/Specific Code
      Use Additional
      • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
      • due to cytoreductive cancer chemotherapy D70.1
    • secondary D70.4
      ICD-10-CM Diagnosis Code D70.4

      Cyclic neutropenia

        2016 2017 2018 2019 2020 Billable/Specific Code
      Applicable To
      • Cyclic hematopoiesis
      • Periodic neutropenia
      • drug-induced D70.2
        ICD-10-CM Diagnosis Code D70.2

        Other drug-induced agranulocytosis

          2016 2017 2018 2019 2020 Billable/Specific Code
        Use Additional
        • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
        • due to cytoreductive cancer chemotherapy D70.1
    • cytoreductive cancer chemotherapy sequela D70.1
  • Leukopenia D72.819
    ICD-10-CM Diagnosis Code D72.819

    Decreased white blood cell count, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Decreased leukocytes, unspecified
    • Leukocytopenia, unspecified
    • Leukopenia
    Type 1 Excludes
    • malignant leukopenia (D70.9)
    • drug induced NEC D70.2
      ICD-10-CM Diagnosis Code D70.2

      Other drug-induced agranulocytosis

        2016 2017 2018 2019 2020 Billable/Specific Code
      Use Additional
      • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
      • due to cytoreductive cancer chemotherapy D70.1
    • chemotherapy D70.1 (cancer)
  • Neutropenia, neutropenic (chronic) (genetic) (idiopathic) (immune) (infantile) (malignant) (pernicious) (splenic) D70.9
    ICD-10-CM Diagnosis Code D70.9

    Neutropenia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • drug-induced D70.2
      ICD-10-CM Diagnosis Code D70.2

      Other drug-induced agranulocytosis

        2016 2017 2018 2019 2020 Billable/Specific Code
      Use Additional
      • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
      • due to cytoreductive cancer chemotherapy D70.1
    • secondary (cyclic) (periodic) (splenic) D70.4
      ICD-10-CM Diagnosis Code D70.4

      Cyclic neutropenia

        2016 2017 2018 2019 2020 Billable/Specific Code
      Applicable To
      • Cyclic hematopoiesis
      • Periodic neutropenia
      • drug-induced D70.2
        ICD-10-CM Diagnosis Code D70.2

        Other drug-induced agranulocytosis

          2016 2017 2018 2019 2020 Billable/Specific Code
        Use Additional
        • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
        • due to cytoreductive cancer chemotherapy D70.1
    • cytoreductive cancer chemotherapy sequela D70.1

ICD-10-CM Codes Adjacent To D70.1
D69.42 Congenital and hereditary thrombocytopenia purpura
D69.49 Other primary thrombocytopenia
D69.5 Secondary thrombocytopenia
D69.51 Posttransfusion purpura
D69.59 Other secondary thrombocytopenia
D69.6 Thrombocytopenia, unspecified
D69.8 Other specified hemorrhagic conditions
D69.9 Hemorrhagic condition, unspecified
D70 Neutropenia
D70.0 Congenital agranulocytosis
D70.1 Agranulocytosis secondary to cancer chemotherapy
D70.2 Other drug-induced agranulocytosis
D70.3 Neutropenia due to infection
D70.4 Cyclic neutropenia
D70.8 Other neutropenia
D70.9 Neutropenia, unspecified
D71 Functional disorders of polymorphonuclear neutrophils
D72 Other disorders of white blood cells
D72.0 Genetic anomalies of leukocytes
D72.1 Eosinophilia
D72.8 Other specified disorders of white blood cells

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.