2023 ICD-10-CM Diagnosis Code D75.1

Secondary polycythemia

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • D75.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM D75.1 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of D75.1 - other international versions of ICD-10 D75.1 may differ.
Applicable To
  • Acquired polycythemia
  • Emotional polycythemia
  • Erythrocytosis NOS
  • Hypoxemic polycythemia
  • Nephrogenous polycythemia
  • Polycythemia due to erythropoietin
  • Polycythemia due to fall in plasma volume
  • Polycythemia due to high altitude
  • Polycythemia due to stress
  • Polycythemia NOS
  • Relative polycythemia
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D75.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • polycythemia neonatorum (
    ICD-10-CM Diagnosis Code P61.1

    Polycythemia neonatorum

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Code on Newborn Record
    P61.1
    )
  • polycythemia vera (
    ICD-10-CM Diagnosis Code D45

    Polycythemia vera

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • familial polycythemia (D75.0)
    • secondary polycythemia (D75.1)
    D45
    )
The following code(s) above D75.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D75.1:
  • D50-D89
    2023 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D75
    ICD-10-CM Diagnosis Code D75

    Other and unspecified diseases of blood and blood-forming organs

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • acute lymphadenitis (L04.-)
    • chronic lymphadenitis (I88.1)
    • enlarged lymph nodes (R59.-)
    • hypergammaglobulinemia NOS (D89.2)
    • lymphadenitis NOS (I88.9)
    • mesenteric lymphadenitis (acute) (chronic) (I88.0)
    Other and unspecified diseases of blood and blood-forming organs
Approximate Synonyms
  • Erythrocytosis
  • Erythrocytosis secondary to tobacco use
  • Erythrocytosis secondary to tobacco use or abuse
  • Polycythemia, secondary
Clinical Information
  • An abnormal increase of the red blood cell in the circulating blood
  • An increase in the total red cell mass of the blood. (Dorland, 27th ed)
  • Increase in the total red cell mass of the blood.
  • Peripheral blood red cell count above the normal range
ICD-10-CM D75.1 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 814 Reticuloendothelial and immunity disorders with mcc
  • 815 Reticuloendothelial and immunity disorders with cc
  • 816 Reticuloendothelial and immunity disorders without cc/mcc

Convert D75.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to D75.1:
  • Type 1 Excludes: D45
    , R71
    , R71
    , D58.2
    ICD-10-CM Diagnosis Code D45

    Polycythemia vera

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Type 1 Excludes
    • familial polycythemia (D75.0)
    • secondary polycythemia (D75.1)
    ICD-10-CM Diagnosis Code R71

    Abnormality of red blood cells

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • anemias (D50-D64)
    • anemia of premature infant (P61.2)
    • benign (familial) polycythemia (D75.0)
    • congenital anemias (P61.2-P61.4)
    • newborn anemia due to isoimmunization (P55.-)
    • polycythemia neonatorum (P61.1)
    • polycythemia NOS (D75.1)
    • polycythemia vera (D45)
    • secondary polycythemia (D75.1)
    ICD-10-CM Diagnosis Code R71

    Abnormality of red blood cells

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • anemias (D50-D64)
    • anemia of premature infant (P61.2)
    • benign (familial) polycythemia (D75.0)
    • congenital anemias (P61.2-P61.4)
    • newborn anemia due to isoimmunization (P55.-)
    • polycythemia neonatorum (P61.1)
    • polycythemia NOS (D75.1)
    • polycythemia vera (D45)
    • secondary polycythemia (D75.1)
    ICD-10-CM Diagnosis Code D58.2

    Other hemoglobinopathies

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Abnormal hemoglobin NOS
    • Congenital Heinz body anemia
    • Hb-C disease
    • Hb-D disease
    • Hb-E disease
    • Hemoglobinopathy NOS
    • Unstable hemoglobin hemolytic disease
    Type 1 Excludes
    • familial polycythemia (D75.0)
    • Hb-M disease (D74.0)
    • hemoglobin E-beta thalassemia (D56.5)
    • hereditary persistence of fetal hemoglobin [HPFH] (D56.4)
    • high-altitude polycythemia (D75.1)
    • methemoglobinemia (D74.-)
    • other hemoglobinopathies with thalassemia (D56.8)
  • Type 2 Excludes: T70.2
    ICD-10-CM Diagnosis Code T70.2

    Other and unspecified effects of high altitude

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • polycythemia due to high altitude (D75.1)

Diagnosis Index entries containing back-references to D75.1:
  • Disease, diseased - see also Syndrome
    • Gaisböck's D75.1 (polycythemia hypertonica)
  • Effect, adverse
    • high altitude NEC T70.29
      ICD-10-CM Diagnosis Code T70.29

      Other effects of high altitude

        2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
      Applicable To
      • Alpine sickness
      • Anoxia due to high altitude
      • Barotrauma NOS
      • Hypobaropathy
      • Mountain sickness
      • polycythemia D75.1
  • Erythremia (acute) C94.0-
    ICD-10-CM Diagnosis Code C94.0-

    Acute erythroid leukemia

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Applicable To
    • Acute myeloid leukemia M6(a)(b)
    • Erythroleukemia
    • secondary D75.1
  • Erythrocytosis (megalosplenic) (secondary) D75.1
    • secondary D75.1
    • stress D75.1
  • Gaisböck's disease D75.1 (polycythemia hypertonica)
  • High
    • altitude effects T70.20
      ICD-10-CM Diagnosis Code T70.20

      Unspecified effects of high altitude

        2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
      • polycythemia D75.1
  • Mountain
    • sickness T70.29
      ICD-10-CM Diagnosis Code T70.29

      Other effects of high altitude

        2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
      Applicable To
      • Alpine sickness
      • Anoxia due to high altitude
      • Barotrauma NOS
      • Hypobaropathy
      • Mountain sickness
      • with polycythemia , acquired D75.1 (acute)
  • Polycythemia (secondary) D75.1
    • due to
      • erythropoietin D75.1
      • fall in plasma volume D75.1
      • high altitude D75.1
      • stress D75.1
    • acquired D75.1
    • emotional D75.1
    • erythropoietin D75.1
    • Gaisböck's D75.1 (hypertonica)
    • high altitude D75.1
    • hypertonica D75.1
    • hypoxemic D75.1
    • nephrogenous D75.1
    • relative D75.1
    • secondary D75.1
    • spurious D75.1
    • stress D75.1
  • Polycytosis cryptogenica D75.1
  • Pseudopolycythemia D75.1
  • Sickness
    • mountain T70.29
      ICD-10-CM Diagnosis Code T70.29

      Other effects of high altitude

        2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
      Applicable To
      • Alpine sickness
      • Anoxia due to high altitude
      • Barotrauma NOS
      • Hypobaropathy
      • Mountain sickness
      • acute D75.1
  • Stress F43.9
    ICD-10-CM Diagnosis Code F43.9

    Reaction to severe stress, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Trauma and stressor-related disorder, NOS
    • Unspecified trauma and stressor-related disorder
    • polycythemia D75.1
  • Syndrome - see also Disease

ICD-10-CM Codes Adjacent To D75.1
D73.8 Other diseases of spleen
D73.81 Neutropenic splenomegaly
D73.89 Other diseases of spleen
D73.9 Disease of spleen, unspecified
D74 Methemoglobinemia
D74.0 Congenital methemoglobinemia
D74.8 Other methemoglobinemias
D74.9 Methemoglobinemia, unspecified
D75 Other and unspecified diseases of blood and blood-forming organs
D75.0 Familial erythrocytosis
D75.1 Secondary polycythemia
D75.8 Other specified diseases of blood and blood-forming organs
D75.81 Myelofibrosis
D75.82 Heparin induced thrombocytopenia (HIT)
D75.821 Non-immune heparin-induced thrombocytopenia
D75.822 Immune-mediated heparin-induced thrombocytopenia
D75.828 Other heparin-induced thrombocytopenia syndrome
D75.829 Heparin-induced thrombocytopenia, unspecified
D75.83 Thrombocytosis
D75.838 Other thrombocytosis
D75.839 …… unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.