2021

  1. ICD-10-CM Codes
    2. ›
  2. D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    3. ›
  3. D70-D77 Other disorders of blood and blood-forming organs
    4. ›
  4. D76- Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
    5. ›
  5. 2021 ICD-10-CM Diagnosis Code D76

2021 ICD-10-CM Diagnosis Code D76

Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

    2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
  • D76 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • Short description: Oth dis with lymphoreticular and reticulohistiocytic tissue
  • The 2021 edition of ICD-10-CM D76 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of D76 - other international versions of ICD-10 D76 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D76. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • (Abt-) Letterer-Siwe disease (
    ICD-10-CM Diagnosis Code C96.0

    Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Histiocytosis X, multisystemic
    • Letterer-Siwe disease
    Type 1 Excludes
    • adult pulmonary Langerhans cell histiocytosis (J84.82)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    • unifocal Langerhans-cell histiocytosis (C96.6)
    C96.0
    )
  • eosinophilic granuloma (
    ICD-10-CM Diagnosis Code C96.6

    Unifocal Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Eosinophilic granuloma
    • Histiocytosis X, unifocal
    • Histiocytosis X NOS
    • Langerhans-cell histiocytosis NOS
    Type 1 Excludes
    • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    C96.6
    )
  • Hand-Schüller-Christian disease (
    ICD-10-CM Diagnosis Code C96.5

    Multifocal and unisystemic Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hand-Schüller-Christian disease
    • Histiocytosis X, multifocal
    Type 1 Excludes
    • multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • unifocal Langerhans-cell histiocytosis (C96.6)
    C96.5
    )
  • histiocytic medullary reticulosis (
    ICD-10-CM Diagnosis Code C96.9

    Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    C96.9
    )
  • histiocytic sarcoma (
    ICD-10-CM Diagnosis Code C96.A

    Histiocytic sarcoma

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Malignant histiocytosis
    C96.A
    )
  • histiocytosis X, multifocal (
    ICD-10-CM Diagnosis Code C96.5

    Multifocal and unisystemic Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hand-Schüller-Christian disease
    • Histiocytosis X, multifocal
    Type 1 Excludes
    • multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • unifocal Langerhans-cell histiocytosis (C96.6)
    C96.5
    )
  • histiocytosis X, unifocal (
    ICD-10-CM Diagnosis Code C96.6

    Unifocal Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Eosinophilic granuloma
    • Histiocytosis X, unifocal
    • Histiocytosis X NOS
    • Langerhans-cell histiocytosis NOS
    Type 1 Excludes
    • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    C96.6
    )
  • Langerhans-cell histiocytosis, multifocal (
    ICD-10-CM Diagnosis Code C96.5

    Multifocal and unisystemic Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Hand-Schüller-Christian disease
    • Histiocytosis X, multifocal
    Type 1 Excludes
    • multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • unifocal Langerhans-cell histiocytosis (C96.6)
    C96.5
    )
  • Langerhans-cell histiocytosis NOS (
    ICD-10-CM Diagnosis Code C96.6

    Unifocal Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Eosinophilic granuloma
    • Histiocytosis X, unifocal
    • Histiocytosis X NOS
    • Langerhans-cell histiocytosis NOS
    Type 1 Excludes
    • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    C96.6
    )
  • Langerhans-cell histiocytosis, unifocal (
    ICD-10-CM Diagnosis Code C96.6

    Unifocal Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Eosinophilic granuloma
    • Histiocytosis X, unifocal
    • Histiocytosis X NOS
    • Langerhans-cell histiocytosis NOS
    Type 1 Excludes
    • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    C96.6
    )
  • leukemic reticuloendotheliosis (
    ICD-10-CM Diagnosis Code C91.4

    Hairy cell leukemia

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Applicable To
    • Leukemic reticuloendotheliosis
    C91.4-
    )
  • lipomelanotic reticulosis (
    ICD-10-CM Diagnosis Code I89.8

    Other specified noninfective disorders of lymphatic vessels and lymph nodes

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Chylocele (nonfilarial)
    • Chylous ascites
    • Chylous cyst
    • Lipomelanotic reticulosis
    • Lymph node or vessel fistula
    • Lymph node or vessel infarction
    • Lymph node or vessel rupture
    I89.8
    )
  • malignant histiocytosis (
    ICD-10-CM Diagnosis Code C96.A

    Histiocytic sarcoma

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Malignant histiocytosis
    C96.A
    )
  • malignant reticulosis (
    ICD-10-CM Diagnosis Code C86.0

    Extranodal NK/T-cell lymphoma, nasal type

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    C86.0
    )
  • nonlipid reticuloendotheliosis (
    ICD-10-CM Diagnosis Code C96.0

    Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Histiocytosis X, multisystemic
    • Letterer-Siwe disease
    Type 1 Excludes
    • adult pulmonary Langerhans cell histiocytosis (J84.82)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    • unifocal Langerhans-cell histiocytosis (C96.6)
    C96.0
    )
The following code(s) above D76 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D76:
  • D50-D89
    2021 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
ICD-10-CM Codes Adjacent To D76
D74.9 Methemoglobinemia, unspecified
D75 Other and unspecified diseases of blood and blood-forming organs
D75.0 Familial erythrocytosis
D75.1 Secondary polycythemia
D75.8 Other specified diseases of blood and blood-forming organs
D75.81 Myelofibrosis
D75.82 Heparin induced thrombocytopenia (HIT)
D75.89 Other specified diseases of blood and blood-forming organs
D75.9 Disease of blood and blood-forming organs, unspecified
D75.A Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
D76 Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue
D76.1 Hemophagocytic lymphohistiocytosis
D76.2 Hemophagocytic syndrome, infection-associated
D76.3 Other histiocytosis syndromes
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
D78 Intraoperative and postprocedural complications of the spleen
D78.0 Intraoperative hemorrhage and hematoma of the spleen complicating a procedure
D78.01 …… on the spleen
D78.02 Intraoperative hemorrhage and hematoma of the spleen complicating other procedure
D78.1 Accidental puncture and laceration of the spleen during a procedure
D78.11 …… on the spleen

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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