Certain disorders involving the immune mechanism D80-D89

Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D80-D89. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • autoimmune disease (systemic) NOS (
    ICD-10-CM Diagnosis Code M35.9

    Systemic involvement of connective tissue, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Autoimmune disease (systemic) NOS
    • Collagen (vascular) disease NOS
  • functional disorders of polymorphonuclear neutrophils (
    ICD-10-CM Diagnosis Code D71

    Functional disorders of polymorphonuclear neutrophils

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Cell membrane receptor complex [CR3] defect
    • Chronic (childhood) granulomatous disease
    • Congenital dysphagocytosis
    • Progressive septic granulomatosis
  • human immunodeficiency virus [HIV] disease (
    ICD-10-CM Diagnosis Code B20

    Human immunodeficiency virus [HIV] disease

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Code First
    • Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
    • acquired immune deficiency syndrome [AIDS]
    • AIDS-related complex [ARC]
    • HIV infection, symptomatic
    Type 1 Excludes
    • asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
    • exposure to HIV virus (Z20.6)
    • inconclusive serologic evidence of HIV (R75)
    Use Additional
    • code(s) to identify all manifestations of HIV infection
Includes Help
"Includes" further defines, or give examples of, the content of the code or category.
  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis
  • D80
    Immunodeficiency with predominantly antibody defects
  • D81
    Combined immunodeficiencies
  • D82
    Immunodeficiency associated with other major defects
  • D83
    Common variable immunodeficiency
  • D84
    Other immunodeficiencies
  • D86
  • D89
    Other disorders involving the immune mechanism, not elsewhere classified
ICD-10-CM Diagnosis Codes D80-*
  • D80 Immunodeficiency with predominantly antibody ...
    • D80.0 Hereditary hypogammaglobulinemia
    • D80.1 Nonfamilial hypogammaglobulinemia
    • D80.2 Selective deficiency of immunoglobulin A [IgA...
    • D80.3 Selective deficiency of immunoglobulin G [IgG...
    • D80.4 Selective deficiency of immunoglobulin M [IgM...
    • D80.5 Immunodeficiency with increased immunoglobuli...
    • D80.6 Antibody deficiency with near-normal immunogl...
    • D80.7 Transient hypogammaglobulinemia of infancy
    • D80.8 Other immunodeficiencies with predominantly a...
    • D80.9 Immunodeficiency with predominantly antibody ...
ICD-10-CM Diagnosis Codes D81-*
  • D81 Combined immunodeficiencies
    • D81.0 Severe combined immunodeficiency [SCID] with ...
    • D81.1 Severe combined immunodeficiency [SCID] with ...
    • D81.2 Severe combined immunodeficiency [SCID] with ...
    • D81.3 Adenosine deaminase [ADA] deficiency
      • D81.30 Adenosine deaminase deficiency, unspecified
      • D81.31 Severe combined immunodeficiency due to adeno...
      • D81.32 Adenosine deaminase 2 deficiency
      • D81.39 Other adenosine deaminase deficiency
    • D81.4 Nezelof's syndrome
    • D81.5 Purine nucleoside phosphorylase [PNP] deficie...
    • D81.6 Major histocompatibility complex class I defi...
    • D81.7 Major histocompatibility complex class II def...
    • D81.8 Other combined immunodeficiencies
      • D81.81 Biotin-dependent carboxylase deficiency
        • D81.810 Biotinidase deficiency
        • D81.818 Other biotin-dependent carboxylase deficiency...
        • D81.819 Biotin-dependent carboxylase deficiency, unsp...
      • D81.82 Activated Phosphoinositide 3-kinase Delta Syn...
      • D81.89 Other combined immunodeficiencies
    • D81.9 Combined immunodeficiency, unspecified
ICD-10-CM Diagnosis Codes D82-*
  • D82 Immunodeficiency associated with other major ...
    • D82.0 Wiskott-Aldrich syndrome
    • D82.1 Di George's syndrome
    • D82.2 Immunodeficiency with short-limbed stature
    • D82.3 Immunodeficiency following hereditary defecti...
    • D82.4 Hyperimmunoglobulin E [IgE] syndrome
    • D82.8 Immunodeficiency associated with other specif...
    • D82.9 Immunodeficiency associated with major defect...
ICD-10-CM Diagnosis Codes D83-*
  • D83 Common variable immunodeficiency
    • D83.0 Common variable immunodeficiency with predomi...
    • D83.1 Common variable immunodeficiency with predomi...
    • D83.2 Common variable immunodeficiency with autoant...
    • D83.8 Other common variable immunodeficiencies
    • D83.9 Common variable immunodeficiency, unspecified...
ICD-10-CM Diagnosis Codes D84-*
  • D84 Other immunodeficiencies
    • D84.0 Lymphocyte function antigen-1 [LFA-1] defect
    • D84.1 Defects in the complement system
    • D84.8 Other specified immunodeficiencies
      • D84.81 Immunodeficiency due to conditions classified...
      • D84.82 Immunodeficiency due to drugs and external ca...
        • D84.821 Immunodeficiency due to drugs
        • D84.822 Immunodeficiency due to external causes
      • D84.89 Other immunodeficiencies
    • D84.9 Immunodeficiency, unspecified
ICD-10-CM Diagnosis Codes D86-*
  • D86 Sarcoidosis
    • D86.0 Sarcoidosis of lung
    • D86.1 Sarcoidosis of lymph nodes
    • D86.2 Sarcoidosis of lung with sarcoidosis of lymph...
    • D86.3 Sarcoidosis of skin
    • D86.8 Sarcoidosis of other sites
      • D86.81 Sarcoid meningitis
      • D86.82 Multiple cranial nerve palsies in sarcoidosis...
      • D86.83 Sarcoid iridocyclitis
      • D86.84 Sarcoid pyelonephritis
      • D86.85 Sarcoid myocarditis
      • D86.86 Sarcoid arthropathy
      • D86.87 Sarcoid myositis
      • D86.89 Sarcoidosis of other sites
    • D86.9 Sarcoidosis, unspecified
ICD-10-CM Diagnosis Codes D89-*
  • D89 Other disorders involving the immune mechanis...
    • D89.0 Polyclonal hypergammaglobulinemia
    • D89.1 Cryoglobulinemia
    • D89.2 Hypergammaglobulinemia, unspecified
    • D89.3 Immune reconstitution syndrome
    • D89.4 Mast cell activation syndrome and related dis...
      • D89.40 Mast cell activation, unspecified
      • D89.41 Monoclonal mast cell activation syndrome
      • D89.42 Idiopathic mast cell activation syndrome
      • D89.43 Secondary mast cell activation
      • D89.44 Hereditary alpha tryptasemia
      • D89.49 Other mast cell activation disorder
    • D89.8 Other specified disorders involving the immun...
      • D89.81 Graft-versus-host disease
        • D89.810 Acute graft-versus-host disease
        • D89.811 Chronic graft-versus-host disease
        • D89.812 Acute on chronic graft-versus-host disease
        • D89.813 …… unspecified
      • D89.82 Autoimmune lymphoproliferative syndrome [ALPS...
      • D89.83 Cytokine release syndrome
      • D89.89 Other specified disorders involving the immun...
    • D89.9 Disorder involving the immune mechanism, unsp...