2023 ICD-10-CM Diagnosis Code D80.9

Immunodeficiency with predominantly antibody defects, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • D80.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Immunodeficiency with predominantly antibody defects, unsp
  • The 2023 edition of ICD-10-CM D80.9 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of D80.9 - other international versions of ICD-10 D80.9 may differ.
The following code(s) above D80.9 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D80.9:
  • D50-D89
    2023 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D80-D89
    2023 ICD-10-CM Range D80-D89

    Certain disorders involving the immune mechanism

    Includes
    • defects in the complement system
    • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
    • sarcoidosis
    Type 1 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • functional disorders of polymorphonuclear neutrophils (D71)
    • human immunodeficiency virus [HIV] disease (B20)
    Certain disorders involving the immune mechanism
Approximate Synonyms
  • Humoral immunoglobulin deficiency
  • Immunodeficiency with predominantly antibody defects
  • Predominant humoral immune deficiency
ICD-10-CM D80.9 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
  • 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
  • 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc

Convert D80.9 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change

Diagnosis Index entries containing back-references to D80.9:
  • Defect, defective Q89.9
    ICD-10-CM Diagnosis Code Q89.9

    Congenital malformation, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code POA Exempt
    Applicable To
    • Congenital anomaly NOS
    • Congenital deformity NOS
    • antibody immunodeficiency D80.9
  • Deficiency, deficient
    • immunity D84.9
      ICD-10-CM Diagnosis Code D84.9

      Immunodeficiency, unspecified

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Immunocompromised NOS
      • Immunodeficient NOS
      • Immunosuppressed NOS
      • humoral D80.9
  • Immunodeficiency D84.9
    ICD-10-CM Diagnosis Code D84.9

    Immunodeficiency, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Immunocompromised NOS
    • Immunodeficient NOS
    • Immunosuppressed NOS
  • Syndrome - see also Disease

ICD-10-CM Codes Adjacent To D80.9
D80 Immunodeficiency with predominantly antibody defects
D80.0 Hereditary hypogammaglobulinemia
D80.1 Nonfamilial hypogammaglobulinemia
D80.2 Selective deficiency of immunoglobulin A [IgA]
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
D80.4 Selective deficiency of immunoglobulin M [IgM]
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
D80.7 Transient hypogammaglobulinemia of infancy
D80.8 Other immunodeficiencies with predominantly antibody defects
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
D81 Combined immunodeficiencies
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.3 Adenosine deaminase [ADA] deficiency
D81.30 Adenosine deaminase deficiency, unspecified
D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
D81.32 Adenosine deaminase 2 deficiency
D81.39 Other adenosine deaminase deficiency
D81.4 Nezelof's syndrome

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.