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ICD-10-CM Codes
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D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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D80-D89
Certain disorders involving the immune mechanism
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D81-
Combined immunodeficiencies
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2022 ICD-10-CM Diagnosis Code D81.39
2022 ICD-10-CM Diagnosis Code D81.39
Other adenosine deaminase deficiency
2020 - New Code 2021 2022 Billable/Specific Code
- D81.39 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2022 edition of ICD-10-CM D81.39 became effective on October 1, 2021.
- This is the American ICD-10-CM version of D81.39 - other international versions of ICD-10 D81.39 may differ.
Applicable To- Adenosine deaminase [ADA] deficiency type 1, NOS
- Adenosine deaminase [ADA] deficiency type 1, without SCID
- Adenosine deaminase [ADA] deficiency type 1, without severe combined immunodeficiency
- Partial ADA deficiency (type 1)
- Partial adenosine deaminase deficiency (type 1)
The following code(s) above
D81.39 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D81.39:
- D50-D89
2022 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanismType 2 Excludes- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- D80-D89
2022 ICD-10-CM Range D80-D89
Certain disorders involving the immune mechanismIncludes- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Type 1 Excludes- autoimmune disease (systemic) NOS (M35.9)
- functional disorders of polymorphonuclear neutrophils (D71)
- human immunodeficiency virus [HIV] disease (B20)
- D81
ICD-10-CM Diagnosis Code D81
Combined immunodeficiencies
2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
Type 1 Excludes- autosomal recessive agammaglobulinemia (Swiss type) (D80.0)
- 642 Inborn and other disorders of metabolism
Code History
- 2020 (effective 10/1/2019): New code
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- Deficiency, deficient
- adenosine deaminase (ADA) D81.30
ICD-10-CM Diagnosis Code D81.30
Adenosine deaminase deficiency, unspecified
2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
- partial D81.39 (type 1)
- specified NEC D81.39
- type 1 D81.39 (without SCID) (without severe combined immunodeficiency)
ICD-10-CM Codes Adjacent To D81.39
D80.8 Other immunodeficiencies with predominantly antibody defects
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
D81 Combined immunodeficiencies
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.3 Adenosine deaminase [ADA] deficiency
D81.30 Adenosine deaminase deficiency, unspecified
D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
D81.32 Adenosine deaminase 2 deficiency
D81.39
Other adenosine deaminase deficiency
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
D81.6 Major histocompatibility complex class I deficiency
D81.7 Major histocompatibility complex class II deficiency
D81.8 Other combined immunodeficiencies
D81.81 Biotin-dependent carboxylase deficiency
D81.818 Other biotin-dependent carboxylase deficiency
D81.89 Other combined immunodeficiencies
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
