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ICD-10-CM Codes
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D50-D89
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D80-D89
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D84-
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2023 ICD-10-CM Diagnosis Code D84.81
2023 ICD-10-CM Diagnosis Code D84.81
Immunodeficiency due to conditions classified elsewhere
2021 - New Code 2022 2023 Billable/Specific Code Manifestation Code
- D84.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2023 edition of ICD-10-CM D84.81 became effective on October 1, 2022.
- This is the American ICD-10-CM version of D84.81 - other international versions of ICD-10 D84.81 may differ.
ICD-10-CM Coding Rules
- D84.81 describes the manifestation of an underlying disease, not the disease itself.
Code FirstCode First Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
Type 1 ExcludesType 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D84.81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- certain disorders involving the immune mechanism (
ICD-10-CM Diagnosis Code D80
Immunodeficiency with predominantly antibody defects
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
ICD-10-CM Diagnosis Code D83
Common variable immunodeficiency
2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
ICD-10-CM Diagnosis Code D84.0
Lymphocyte function antigen-1 [LFA-1] defect
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
ICD-10-CM Diagnosis Code D84.1
Defects in the complement system
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- C1 esterase inhibitor [C1-INH] deficiency
ICD-10-CM Diagnosis Code D84.9
Immunodeficiency, unspecified
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- Immunocompromised NOS
- Immunodeficient NOS
- Immunosuppressed NOS
- human immunodeficiency virus [HIV] disease (
ICD-10-CM Diagnosis Code B20
Human immunodeficiency virus [HIV] disease
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Code First- Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
Includes- acquired immune deficiency syndrome [AIDS]
- AIDS-related complex [ARC]
- HIV infection, symptomatic
Type 1 Excludes- asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
- exposure to HIV virus (Z20.6)
- inconclusive serologic evidence of HIV (R75)
Use Additional- code(s) to identify all manifestations of HIV infection
The following code(s) above
D84.81 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D84.81:
- 814 Reticuloendothelial and immunity disorders with mcc
- 815 Reticuloendothelial and immunity disorders with cc
- 816 Reticuloendothelial and immunity disorders without cc/mcc
Code History
- 2021 (effective 10/1/2020): New code
- 2022 (effective 10/1/2021): No change
- 2023 (effective 10/1/2022): No change
- Immunodeficiency D84.9
ICD-10-CM Diagnosis Code D84.9
Immunodeficiency, unspecified
2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
Applicable To- Immunocompromised NOS
- Immunodeficient NOS
- Immunosuppressed NOS
- due to
- conditions classified elsewhere D84.81
ICD-10-CM Codes Adjacent To D84.81
D83 Common variable immunodeficiency
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
D83.8 Other common variable immunodeficiencies
D83.9 Common variable immunodeficiency, unspecified
D84 Other immunodeficiencies
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
D84.1 Defects in the complement system
D84.8 Other specified immunodeficiencies
D84.81
Immunodeficiency due to conditions classified elsewhere
D84.82 Immunodeficiency due to drugs and external causes
D84.821 Immunodeficiency due to drugs
D84.822 Immunodeficiency due to external causes
D84.89 Other immunodeficiencies
D84.9 Immunodeficiency, unspecified
D86.0 Sarcoidosis of lung
D86.1 Sarcoidosis of lymph nodes
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
D86.3 Sarcoidosis of skin
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
