2021

  1. ICD-10-CM Codes
    2. ›
  2. D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    3. ›
  3. D80-D89 Certain disorders involving the immune mechanism
    4. ›
  4. D89- Other disorders involving the immune mechanism, not elsewhere classified
    5. ›
  5. 2021 ICD-10-CM Diagnosis Code D89.0

2021 ICD-10-CM Diagnosis Code D89.0

Polyclonal hypergammaglobulinemia

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • D89.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM D89.0 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of D89.0 - other international versions of ICD-10 D89.0 may differ.
Applicable To
  • Benign hypergammaglobulinemic purpura
  • Polyclonal gammopathy NOS
The following code(s) above D89.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D89.0:
  • D50-D89
    2021 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D80-D89
    2021 ICD-10-CM Range D80-D89

    Certain disorders involving the immune mechanism

    Includes
    • defects in the complement system
    • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
    • sarcoidosis
    Type 1 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • functional disorders of polymorphonuclear neutrophils (D71)
    • human immunodeficiency virus [HIV] disease (B20)
    Certain disorders involving the immune mechanism
  • D89
    ICD-10-CM Diagnosis Code D89

    Other disorders involving the immune mechanism, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • hyperglobulinemia NOS (R77.1)
    • monoclonal gammopathy (of undetermined significance) (D47.2)
    Type 2 Excludes
    • transplant failure and rejection (T86.-)
    Other disorders involving the immune mechanism, not elsewhere classified
Approximate Synonyms
  • Benign primary hypergammaglobulinemic purpura
  • Hypergammaglobulinemia, polyclonal
  • Purpura, hypergammaglobulinemic, benign primary
ICD-10-CM D89.0 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 814 Reticuloendothelial and immunity disorders with mcc
  • 815 Reticuloendothelial and immunity disorders with cc
  • 816 Reticuloendothelial and immunity disorders without cc/mcc

Convert D89.0 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
Code annotations containing back-references to D89.0:
  • Type 1 Excludes: D69
    , D69
    , E88.0
    ICD-10-CM Diagnosis Code D69

    Purpura and other hemorrhagic conditions

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • benign hypergammaglobulinemic purpura (D89.0)
    • cryoglobulinemic purpura (D89.1)
    • essential (hemorrhagic) thrombocythemia (D47.3)
    • hemorrhagic thrombocythemia (D47.3)
    • purpura fulminans (D65)
    • thrombotic thrombocytopenic purpura (M31.1)
    • Waldenström hypergammaglobulinemic purpura (D89.0)
    ICD-10-CM Diagnosis Code D69

    Purpura and other hemorrhagic conditions

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • benign hypergammaglobulinemic purpura (D89.0)
    • cryoglobulinemic purpura (D89.1)
    • essential (hemorrhagic) thrombocythemia (D47.3)
    • hemorrhagic thrombocythemia (D47.3)
    • purpura fulminans (D65)
    • thrombotic thrombocytopenic purpura (M31.1)
    • Waldenström hypergammaglobulinemic purpura (D89.0)
    ICD-10-CM Diagnosis Code E88.0

    Disorders of plasma-protein metabolism, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • monoclonal gammopathy (of undetermined significance) (D47.2)
    • polyclonal hypergammaglobulinemia (D89.0)
    • Waldenström macroglobulinemia (C88.0)
    Type 2 Excludes
    • disorder of lipoprotein metabolism (E78.-)

Diagnosis Index entries containing back-references to D89.0:
  • Gammopathy (of undetermined significance [MGUS]) D47.2
    ICD-10-CM Diagnosis Code D47.2

    Monoclonal gammopathy

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Monoclonal gammopathy of undetermined significance [MGUS]
    • polyclonal D89.0
  • Hypergammaglobulinemia D89.2
    ICD-10-CM Diagnosis Code D89.2

    Hypergammaglobulinemia, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    • polyclonal D89.0
    • Waldenström D89.0
  • Purpura D69.2
    ICD-10-CM Diagnosis Code D69.2

    Other nonthrombocytopenic purpura

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    Applicable To
    • Purpura NOS
    • Purpura simplex
    • Senile purpura
    • hypergammaglobulinemic D89.0 (benign) (Waldenström)
  • Waldenström
    • hypergammaglobulinemia D89.0

ICD-10-CM Codes Adjacent To D89.0
D86.81 Sarcoid meningitis
D86.82 Multiple cranial nerve palsies in sarcoidosis
D86.83 Sarcoid iridocyclitis
D86.84 Sarcoid pyelonephritis
D86.85 Sarcoid myocarditis
D86.86 Sarcoid arthropathy
D86.87 Sarcoid myositis
D86.89 Sarcoidosis of other sites
D86.9 Sarcoidosis, unspecified
D89 Other disorders involving the immune mechanism, not elsewhere classified
D89.0 Polyclonal hypergammaglobulinemia
D89.1 Cryoglobulinemia
D89.2 Hypergammaglobulinemia, unspecified
D89.3 Immune reconstitution syndrome
D89.4 Mast cell activation syndrome and related disorders
D89.40 Mast cell activation, unspecified
D89.41 Monoclonal mast cell activation syndrome
D89.42 Idiopathic mast cell activation syndrome
D89.43 Secondary mast cell activation
D89.49 Other mast cell activation disorder
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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