2019 ICD-10-CM Diagnosis Code D89.1

Cryoglobulinemia

    2016 2017 2018 2019 Billable/Specific Code
  • D89.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM D89.1 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of D89.1 - other international versions of ICD-10 D89.1 may differ.
Applicable To
  • Cryoglobulinemic purpura
  • Cryoglobulinemic vasculitis
  • Essential cryoglobulinemia
  • Idiopathic cryoglobulinemia
  • Mixed cryoglobulinemia
  • Primary cryoglobulinemia
  • Secondary cryoglobulinemia
The following code(s) above D89.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D89.1:
  • D50-D89
    2019 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D80-D89
    2019 ICD-10-CM Range D80-D89

    Certain disorders involving the immune mechanism

    Includes
    • defects in the complement system
    • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
    • sarcoidosis
    Type 1 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • functional disorders of polymorphonuclear neutrophils (D71)
    • human immunodeficiency virus [HIV] disease (B20)
    Certain disorders involving the immune mechanism
  • D89
    ICD-10-CM Diagnosis Code D89

    Other disorders involving the immune mechanism, not elsewhere classified

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • hyperglobulinemia NOS (R77.1)
    • monoclonal gammopathy (of undetermined significance) (D47.2)
    Type 2 Excludes
    • transplant failure and rejection (T86.-)
    Other disorders involving the immune mechanism, not elsewhere classified
Approximate Synonyms
  • Cryoglobulinemia due to chronic hepatitis c
Clinical Information
  • A condition characterized by the presence of abnormal quantities of cryoglobulins in the blood. Upon cold exposure, these abnormal proteins precipitate into the microvasculature leading to restricted blood flow in the exposed areas.
  • A condition characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins that precipitate within the microvasculature on exposure to cold; microvasculature effects of cryoglobulinemia may result in restricted tissue blood flow, tissue hypoxia, and tissue necrosis.
ICD-10-CM D89.1 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 820 Lymphoma and leukemia with major o.r. Procedure with mcc
  • 821 Lymphoma and leukemia with major o.r. Procedure with cc
  • 822 Lymphoma and leukemia with major o.r. Procedure without cc/mcc
  • 823 Lymphoma and non-acute leukemia with other procedure with mcc
  • 824 Lymphoma and non-acute leukemia with other procedure with cc
  • 825 Lymphoma and non-acute leukemia with other procedure without cc/mcc
  • 840 Lymphoma and non-acute leukemia with mcc
  • 841 Lymphoma and non-acute leukemia with cc
  • 842 Lymphoma and non-acute leukemia without cc/mcc

Convert D89.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to D89.1:
  • Code First: N08
    , N16
    , J99
    ICD-10-CM Diagnosis Code N08

    Glomerular disorders in diseases classified elsewhere

      2016 2017 2018 2019 Billable/Specific Code Manifestation Code
    Applicable To
    • Glomerulonephritis
    • Nephritis
    • Nephropathy
    Code First
    Type 1 Excludes
    • glomerulonephritis, nephritis and nephropathy (in):
    • antiglomerular basement membrane disease (M31.0)
    • diabetes (E08-E13 with .21)
    • gonococcal (A54.21)
    • Goodpasture's syndrome (M31.0)
    • hemolytic-uremic syndrome (D59.3)
    • lupus (M32.14)
    • mumps (B26.83)
    • syphilis (A52.75)
    • systemic lupus erythematosus (M32.14)
    • Wegener's granulomatosis (M31.31)
    • pyelonephritis in diseases classified elsewhere (N16)
    • renal tubulo-interstitial disorders classified elsewhere (N16)
    ICD-10-CM Diagnosis Code N16

    Renal tubulo-interstitial disorders in diseases classified elsewhere

      2016 2017 2018 2019 Billable/Specific Code Manifestation Code
    Applicable To
    • Pyelonephritis
    • Tubulo-interstitial nephritis
    Code First
    Type 1 Excludes
    • diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
    • pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
    • pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
    • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
    • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
    • pyelonephritis and tubulo-interstitial nephritis in sicca syndrome [Sjogren's] (M35.04)
    • pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
    • pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
    • renal tubular degeneration in diabetes (E08-E13 with .29)
    • syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)
    ICD-10-CM Diagnosis Code J99

    Respiratory disorders in diseases classified elsewhere

      2016 2017 2018 2019 Billable/Specific Code Manifestation Code
    Code First
    • underlying disease, such as:
    • amyloidosis (E85.-)
    • ankylosing spondylitis (M45)
    • congenital syphilis (A50.5)
    • cryoglobulinemia (D89.1)
    • early congenital syphilis (A50.0)
    • plasminogen deficiency (E88.02)
    • schistosomiasis (B65.0-B65.9)
    Type 1 Excludes
  • Type 1 Excludes: D69
    ICD-10-CM Diagnosis Code D69

    Purpura and other hemorrhagic conditions

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • benign hypergammaglobulinemic purpura (D89.0)
    • cryoglobulinemic purpura (D89.1)
    • essential (hemorrhagic) thrombocythemia (D47.3)
    • hemorrhagic thrombocythemia (D47.3)
    • purpura fulminans (D65)
    • thrombotic thrombocytopenic purpura (M31.1)
    • Waldenström hypergammaglobulinemic purpura (D89.0)

Diagnosis Index entries containing back-references to D89.1:
  • Cryoglobulinemia (essential) (idiopathic) (mixed) (primary) (purpura) (secondary) (vasculitis) D89.1
    • with lung involvement D89.1
  • Disorder (of) - see also Disease
    • glomerular (in) N05.9
      ICD-10-CM Diagnosis Code N05.9

      Unspecified nephritic syndrome with unspecified morphologic changes

        2016 2017 2018 2019 Billable/Specific Code
      • cryoglobulinemia D89.1
    • tubulo-interstitial (in)
      • mixed cryoglobulinemia D89.1
  • Glomerulonephritis N05.9
    - see also Nephritis
    ICD-10-CM Diagnosis Code N05.9

    Unspecified nephritic syndrome with unspecified morphologic changes

      2016 2017 2018 2019 Billable/Specific Code
    • in (due to)
      • cryoglobulinemia D89.1
  • Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic) N05.9
    ICD-10-CM Diagnosis Code N05.9

    Unspecified nephritic syndrome with unspecified morphologic changes

      2016 2017 2018 2019 Billable/Specific Code
    • tubulo-interstitial (in) N12
      ICD-10-CM Diagnosis Code N12

      Tubulo-interstitial nephritis, not specified as acute or chronic

        2016 2017 2018 2019 Billable/Specific Code
      Applicable To
      • Interstitial nephritis NOS
      • Pyelitis NOS
      • Pyelonephritis NOS
      Type 1 Excludes
      • calculous pyelonephritis (N20.9)
      • due to
        • cryoglobulinemia D89.1
  • Purpura D69.2
    ICD-10-CM Diagnosis Code D69.2

    Other nonthrombocytopenic purpura

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Purpura NOS
    • Purpura simplex
    • Senile purpura
    • cryoglobulinemic D89.1
  • Pyelonephritis - see also Nephritis, tubulo-interstitial
    • in (due to)
      • cryoglobulinemia D89.1 (mixed)
  • Vasculitis I77.6
    ICD-10-CM Diagnosis Code I77.6

    Arteritis, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Aortitis NOS
    • Endarteritis NOS
    Type 1 Excludes
    • cryoglobulinemic D89.1

ICD-10-CM Codes Adjacent To D89.1
D86.82 Multiple cranial nerve palsies in sarcoidosis
D86.83 Sarcoid iridocyclitis
D86.84 Sarcoid pyelonephritis
D86.85 Sarcoid myocarditis
D86.86 Sarcoid arthropathy
D86.87 Sarcoid myositis
D86.89 Sarcoidosis of other sites
D86.9 Sarcoidosis, unspecified
D89 Other disorders involving the immune mechanism, not elsewhere classified
D89.0 Polyclonal hypergammaglobulinemia
D89.1 Cryoglobulinemia
D89.2 Hypergammaglobulinemia, unspecified
D89.3 Immune reconstitution syndrome
D89.4 Mast cell activation syndrome and related disorders
D89.40 Mast cell activation, unspecified
D89.41 Monoclonal mast cell activation syndrome
D89.42 Idiopathic mast cell activation syndrome
D89.43 Secondary mast cell activation
D89.49 Other mast cell activation disorder
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
D89.81 Graft-versus-host disease

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.