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ICD-10-CM Codes
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D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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D80-D89
Certain disorders involving the immune mechanism
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D89-
Other disorders involving the immune mechanism, not elsewhere classified
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2021 ICD-10-CM Diagnosis Code D89.812
2021 ICD-10-CM Diagnosis Code D89.812
Acute on chronic graft-versus-host disease
2016 2017 2018 2019 2020 2021 Billable/Specific Code
- D89.812 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2021 edition of ICD-10-CM D89.812 became effective on October 1, 2020.
- This is the American ICD-10-CM version of D89.812 - other international versions of ICD-10 D89.812 may differ.
The following code(s) above
D89.812 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
D89.812:
- D50-D89
2021 ICD-10-CM Range D50-D89
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanismType 2 Excludes- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - D80-D89
2021 ICD-10-CM Range D80-D89
Certain disorders involving the immune mechanismIncludes- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Type 1 Excludes- autoimmune disease (systemic) NOS (M35.9)
- functional disorders of polymorphonuclear neutrophils (D71)
- human immunodeficiency virus [HIV] disease (B20)
Certain disorders involving the immune mechanism - D89
ICD-10-CM Diagnosis Code D89
Other disorders involving the immune mechanism, not elsewhere classified
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Type 1 Excludes- hyperglobulinemia NOS (R77.1)
- monoclonal gammopathy (of undetermined significance) (D47.2)
Type 2 Excludes- transplant failure and rejection (T86.-)
Other disorders involving the immune mechanism, not elsewhere classified - D89.81
ICD-10-CM Diagnosis Code D89.81
Graft-versus-host disease
2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
Code First- underlying cause, such as:
- complications of transplanted organs and tissue (T86.-)
- complications of blood transfusion (T80.89)
Use Additional- code to identify associated manifestations, such as:
- desquamative dermatitis (L30.8)
- diarrhea (R19.7)
- elevated bilirubin (R17)
- hair loss (L65.9)
Graft-versus-host disease
Approximate Synonyms
- Acute chronic graft versus host disease
- Acute on chronic graft versus host disease
- Acute on chronic graft versus host disease due to kidney transplant
- Graft versus host disease due to kidney transplant
ICD-10-CM D89.812 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
- 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
- 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
- 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc
Convert D89.812 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
ICD-10-CM Codes Adjacent To D89.812
D89.4 Mast cell activation syndrome and related disorders
D89.40 Mast cell activation, unspecified
D89.41 Monoclonal mast cell activation syndrome
D89.42 Idiopathic mast cell activation syndrome
D89.43 Secondary mast cell activation
D89.49 Other mast cell activation disorder
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
D89.81 Graft-versus-host disease
D89.810 Acute graft-versus-host disease
D89.811 Chronic graft-versus-host disease
D89.812
Acute on chronic graft-versus-host disease
D89.82 Autoimmune lymphoproliferative syndrome [ALPS]
D89.83 Cytokine release syndrome
D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.