2021 ICD-10-CM Diagnosis Code D89.813

Graft-versus-host disease, unspecified

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • D89.813 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM D89.813 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of D89.813 - other international versions of ICD-10 D89.813 may differ.
The following code(s) above D89.813 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to D89.813:
  • D50-D89
    2021 ICD-10-CM Range D50-D89

    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

    Type 2 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • certain conditions originating in the perinatal period (P00-P96)
    • complications of pregnancy, childbirth and the puerperium (O00-O9A)
    • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
    • endocrine, nutritional and metabolic diseases (E00-E88)
    • human immunodeficiency virus [HIV] disease (B20)
    • injury, poisoning and certain other consequences of external causes (S00-T88)
    • neoplasms (C00-D49)
    • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
    Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
  • D80-D89
    2021 ICD-10-CM Range D80-D89

    Certain disorders involving the immune mechanism

    Includes
    • defects in the complement system
    • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
    • sarcoidosis
    Type 1 Excludes
    • autoimmune disease (systemic) NOS (M35.9)
    • functional disorders of polymorphonuclear neutrophils (D71)
    • human immunodeficiency virus [HIV] disease (B20)
    Certain disorders involving the immune mechanism
  • D89
    ICD-10-CM Diagnosis Code D89

    Other disorders involving the immune mechanism, not elsewhere classified

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • hyperglobulinemia NOS (R77.1)
    • monoclonal gammopathy (of undetermined significance) (D47.2)
    Type 2 Excludes
    • transplant failure and rejection (T86.-)
    Other disorders involving the immune mechanism, not elsewhere classified
  • D89.81
    ICD-10-CM Diagnosis Code D89.81

    Graft-versus-host disease

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Code First
    • underlying cause, such as:
    • complications of transplanted organs and tissue (T86.-)
    • complications of blood transfusion (T80.89)
    Use Additional
    • code to identify associated manifestations, such as:
    • desquamative dermatitis (L30.8)
    • diarrhea (R19.7)
    • elevated bilirubin (R17)
    • hair loss (L65.9)
    Graft-versus-host disease
Approximate Synonyms
  • Graft versus host disease
  • Graft versus host disease due to kidney transplant
Clinical Information
  • A disease caused when cells from a donated stem cell graft attack the normal tissue of the transplant patient. Symptoms include jaundice, skin rash or blisters, a dry mouth, or dry eyes.
  • An incompatibility reaction (which may be fatal) in a subject (host) of low immunological competence (deficient lymphoid tissue) who has been the recipient of immunologically competent lymphoid tissue from a donor who lacks at least one antigen possessed by the recipient host; the reaction, or disease, is the result of action of the transplanted cells against those host tissues that possess the antigen not possessed by the donor. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin.
  • Caused by immunologically competent t cells in the graft recognizing and attacking host tissues as foreign; clinical symptoms include skin rashes, diarrhea, and abnormal liver functions.
  • The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft vs host reaction.
ICD-10-CM D89.813 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 808 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with mcc
  • 809 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders with cc
  • 810 Major hematological and immunological diagnoses except sickle cell crisis and coagulation disorders without cc/mcc

Convert D89.813 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to D89.813:

ICD-10-CM Codes Adjacent To D89.813
D89.40 Mast cell activation, unspecified
D89.41 Monoclonal mast cell activation syndrome
D89.42 Idiopathic mast cell activation syndrome
D89.43 Secondary mast cell activation
D89.49 Other mast cell activation disorder
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
D89.81 Graft-versus-host disease
D89.810 Acute graft-versus-host disease
D89.811 Chronic graft-versus-host disease
D89.812 Acute on chronic graft-versus-host disease
D89.813 …… unspecified
D89.82 Autoimmune lymphoproliferative syndrome [ALPS]
D89.83 Cytokine release syndrome
D89.831 …… grade 1
D89.832 …… grade 2
D89.833 …… grade 3
D89.834 …… grade 4
D89.835 …… grade 5
D89.839 …… grade unspecified
D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified
D89.9 Disorder involving the immune mechanism, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.