2020 ICD-10-CM Diagnosis Code E08.21

Diabetes mellitus due to underlying condition with diabetic nephropathy

    2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code
  • E08.21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • Short description: Diabetes due to underlying condition w diabetic nephropathy
  • The 2020 edition of ICD-10-CM E08.21 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E08.21 - other international versions of ICD-10 E08.21 may differ.
ICD-10-CM Coding Rules
  • E08.21 describes the manifestation of an underlying disease, not the disease itself.
Applicable To
  • Diabetes mellitus due to underlying condition with intercapillary glomerulosclerosis
  • Diabetes mellitus due to underlying condition with intracapillary glomerulonephrosis
  • Diabetes mellitus due to underlying condition with Kimmelstiel-Wilson disease
The following code(s) above E08.21 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E08.21:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E08
    ICD-10-CM Diagnosis Code E08

    Diabetes mellitus due to underlying condition

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Code First
    • the underlying condition, such as:
    • congenital rubella (P35.0)
    • Cushing's syndrome (E24.-)
    • cystic fibrosis (E84.-)
    • malignant neoplasm (C00-C96)
    • malnutrition (E40-E46)
    • pancreatitis and other diseases of the pancreas (K85-K86.-)
    Type 1 Excludes
    • drug or chemical induced diabetes mellitus (E09.-)
    • gestational diabetes (O24.4-)
    • neonatal diabetes mellitus (P70.2)
    • postpancreatectomy diabetes mellitus (E13.-)
    • postprocedural diabetes mellitus (E13.-)
    • secondary diabetes mellitus NEC (E13.-)
    • type 1 diabetes mellitus (E10.-)
    • type 2 diabetes mellitus (E11.-)
    Use Additional
    • code to identify control using:
    • insulin (Z79.4)
    • oral antidiabetic drugs (Z79.84)
    • oral hypoglycemic drugs (Z79.84)
    Diabetes mellitus due to underlying condition
ICD-10-CM E08.21 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 008 Simultaneous pancreas and kidney transplant
  • 010 Pancreas transplant
  • 698 Other kidney and urinary tract diagnoses with mcc
  • 699 Other kidney and urinary tract diagnoses with cc
  • 700 Other kidney and urinary tract diagnoses without cc/mcc

Convert E08.21 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to E08.21:
  • Diabetes, diabetic (mellitus) (sugar) E11.9
    ICD-10-CM Diagnosis Code E11.9

    Type 2 diabetes mellitus without complications

      2016 2017 2018 2019 2020 Billable/Specific Code Questionable As Admission Dx
    • due to underlying condition E08.9
      ICD-10-CM Diagnosis Code E08.9

      Diabetes mellitus due to underlying condition without complications

        2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code
      • with
        • glomerulonephrosis, intracapillary E08.21
        • glomerulosclerosis, intercapillary E08.21
        • Kimmelsteil-WIlson disease E08.21
        • nephropathy E08.21

ICD-10-CM Codes Adjacent To E08.21
E07.89 Other specified disorders of thyroid
E07.9 Disorder of thyroid, unspecified
E08 Diabetes mellitus due to underlying condition
E08.0 Diabetes mellitus due to underlying condition with hyperosmolarity
E08.00 …… without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)
E08.01 …… with coma
E08.1 Diabetes mellitus due to underlying condition with ketoacidosis
E08.10 …… without coma
E08.11 …… with coma
E08.2 Diabetes mellitus due to underlying condition with kidney complications
E08.21 Diabetes mellitus due to underlying condition with diabetic nephropathy
E08.22 Diabetes mellitus due to underlying condition with diabetic chronic kidney disease
E08.29 Diabetes mellitus due to underlying condition with other diabetic kidney complication
E08.3 Diabetes mellitus due to underlying condition with ophthalmic complications
E08.31 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy
E08.311 …… with macular edema
E08.319 …… without macular edema
E08.32 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy
E08.321 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema
E08.3211 …… right eye
E08.3212 …… left eye

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.