2022

  1. ICD-10-CM Codes
    2. ›
  2. E00-E89 Endocrine, nutritional and metabolic diseases
    3. ›
  3. E08-E13 Diabetes mellitus
    4. ›
  4. E10- Type 1 diabetes mellitus
    5. ›
  5. 2022 ICD-10-CM Diagnosis Code E10.21

2022 ICD-10-CM Diagnosis Code E10.21

Type 1 diabetes mellitus with diabetic nephropathy

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  • E10.21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2022 edition of ICD-10-CM E10.21 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of E10.21 - other international versions of ICD-10 E10.21 may differ.
Applicable To
  • Type 1 diabetes mellitus with intercapillary glomerulosclerosis
  • Type 1 diabetes mellitus with intracapillary glomerulonephrosis
  • Type 1 diabetes mellitus with Kimmelstiel-Wilson disease
The following code(s) above E10.21 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E10.21:
  • E00-E89
    2022 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E10
    ICD-10-CM Diagnosis Code E10

    Type 1 diabetes mellitus

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Includes
    • brittle diabetes (mellitus)
    • diabetes (mellitus) due to autoimmune process
    • diabetes (mellitus) due to immune mediated pancreatic islet beta-cell destruction
    • idiopathic diabetes (mellitus)
    • juvenile onset diabetes (mellitus)
    • ketosis-prone diabetes (mellitus)
    Type 1 Excludes
    • diabetes mellitus due to underlying condition (E08.-)
    • drug or chemical induced diabetes mellitus (E09.-)
    • gestational diabetes (O24.4-)
    • hyperglycemia NOS (R73.9)
    • neonatal diabetes mellitus (P70.2)
    • postpancreatectomy diabetes mellitus (E13.-)
    • postprocedural diabetes mellitus (E13.-)
    • secondary diabetes mellitus NEC (E13.-)
    • type 2 diabetes mellitus (E11.-)
    Type 1 diabetes mellitus
Approximate Synonyms
  • Diabetes type 1 with diabetic nephropathy
  • Renal disorder associated with type i diabetes mellitus
ICD-10-CM E10.21 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 008 Simultaneous pancreas and kidney transplant
  • 010 Pancreas transplant
  • 019 Simultaneous pancreas and kidney transplant with hemodialysis
  • 673 Other kidney and urinary tract procedures with mcc
  • 674 Other kidney and urinary tract procedures with cc
  • 675 Other kidney and urinary tract procedures without cc/mcc
  • 698 Other kidney and urinary tract diagnoses with mcc
  • 699 Other kidney and urinary tract diagnoses with cc
  • 700 Other kidney and urinary tract diagnoses without cc/mcc

Convert E10.21 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change

Diagnosis Index entries containing back-references to E10.21:
  • Diabetes, diabetic (mellitus) (sugar) E11.9
    ICD-10-CM Diagnosis Code E11.9

    Type 2 diabetes mellitus without complications

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code Questionable As Admission Dx
    • type 1 E10.9
      ICD-10-CM Diagnosis Code E10.9

      Type 1 diabetes mellitus without complications

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      • with
        • glomerulonephrosis, intracapillary E10.21
        • glomerulosclerosis, intercapillary E10.21
        • Kimmelsteil-Wilson disease E10.21
        • nephropathy E10.21

ICD-10-CM Codes Adjacent To E10.21
E09.649 …… without coma
E09.65 Drug or chemical induced diabetes mellitus with hyperglycemia
E09.69 Drug or chemical induced diabetes mellitus with other specified complication
E09.8 Drug or chemical induced diabetes mellitus with unspecified complications
E09.9 Drug or chemical induced diabetes mellitus without complications
E10 Type 1 diabetes mellitus
E10.1 Type 1 diabetes mellitus with ketoacidosis
E10.10 …… without coma
E10.11 …… with coma
E10.2 Type 1 diabetes mellitus with kidney complications
E10.21 Type 1 diabetes mellitus with diabetic nephropathy
E10.22 Type 1 diabetes mellitus with diabetic chronic kidney disease
E10.29 Type 1 diabetes mellitus with other diabetic kidney complication
E10.3 Type 1 diabetes mellitus with ophthalmic complications
E10.31 Type 1 diabetes mellitus with unspecified diabetic retinopathy
E10.311 …… with macular edema
E10.319 …… without macular edema
E10.32 Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy
E10.321 Type 1 diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema
E10.3211 …… right eye
E10.3212 …… left eye

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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