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ICD-10-CM Codes
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E00-E89
Endocrine, nutritional and metabolic diseases
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E15-E16
Other disorders of glucose regulation and pancreatic internal secretion
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E16-
Other disorders of pancreatic internal secretion
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2021 ICD-10-CM Diagnosis Code E16.0
2021 ICD-10-CM Diagnosis Code E16.0
Drug-induced hypoglycemia without coma
2016 2017 2018 2019 2020 2021 Billable/Specific Code
- E16.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2021 edition of ICD-10-CM E16.0 became effective on October 1, 2020.
- This is the American ICD-10-CM version of E16.0 - other international versions of ICD-10 E16.0 may differ.
Use AdditionalUse Additional Help
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation. In most cases the manifestation codes will have in the code title, "in diseases classified elsewhere." Codes with this title are a component of the etiology/manifestation convention. The code title indicates that it is a manifestation code. "In diseases classified elsewhere" codes are never permitted to be used as first listed or principle diagnosis codes. They must be used in conjunction with an underlying condition code and they must be listed following the underlying condition.
- code for adverse effect, if applicable, to identify drug (T36-T50
ICD-10-CM Range T36-T50
Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substancesCode First- , for adverse effects, the nature of the adverse effect, such as:
- adverse effect NOS (T88.7)
- aspirin gastritis (K29.-)
- blood disorders (D56-D76)
- contact dermatitis (L23-L25)
- dermatitis due to substances taken internally (L27.-)
- nephropathy (N14.0-N14.2)
Includes- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Note- The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
Type 1 Excludes- toxic reaction to local anesthesia in pregnancy (O29.3-)
Type 2 Excludes- abuse and dependence of psychoactive substances (F10-F19)
- abuse of non-dependence-producing substances (F55.-)
- immunodeficiency due to drugs (D84.821)
- drug reaction and poisoning affecting newborn (P00-P96)
- pathological drug intoxication (inebriation) (F10-F19)
Use Additional- code(s) to specify:
- manifestations of poisoning
- underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
- underdosing of medication regimen (Z91.12-, Z91.13-)
- T36 Poisoning by, adverse effect of and unde...
- T37 Poisoning by, adverse effect of and unde...
- T38 Poisoning by, adverse effect of and unde...
- T39 Poisoning by, adverse effect of and unde...
- T40 Poisoning by, adverse effect of and unde...
- T41 Poisoning by, adverse effect of and unde...
- T42 Poisoning by, adverse effect of and unde...
- T43 Poisoning by, adverse effect of and unde...
- T44 Poisoning by, adverse effect of and unde...
- T45 Poisoning by, adverse effect of and unde...
- T46 Poisoning by, adverse effect of and unde...
- T47 Poisoning by, adverse effect of and unde...
- T48 Poisoning by, adverse effect of and unde...
- T49 Poisoning by, adverse effect of and unde...
- T50 Poisoning by, adverse effect of and unde...
Type 1 ExcludesType 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E16.0. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
The following code(s) above
E16.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
E16.0:
- Drug induced hypoglycemia
ICD-10-CM E16.0 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
- 643 Endocrine disorders with mcc
- 644 Endocrine disorders with cc
- 645 Endocrine disorders without cc/mcc
Convert E16.0 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- Hypoglycemia (spontaneous) E16.2
ICD-10-CM Diagnosis Code E16.2
Hypoglycemia, unspecified
2016 2017 2018 2019 2020 2021 Billable/Specific Code
- Reaction - see also Disorder
ICD-10-CM Codes Adjacent To E16.0
E13.638 Other specified diabetes mellitus with other oral complications
E13.64 Other specified diabetes mellitus with hypoglycemia
E13.65 Other specified diabetes mellitus with hyperglycemia
E13.69 Other specified diabetes mellitus with other specified complication
E13.8 Other specified diabetes mellitus with unspecified complications
E13.9 Other specified diabetes mellitus without complications
E15 Nondiabetic hypoglycemic coma
E16 Other disorders of pancreatic internal secretion
E16.0
Drug-induced hypoglycemia without coma
E16.2 Hypoglycemia, unspecified
E16.3 Increased secretion of glucagon
E16.4 Increased secretion of gastrin
E16.8 Other specified disorders of pancreatic internal secretion
E16.9 Disorder of pancreatic internal secretion, unspecified
E20.0 Idiopathic hypoparathyroidism
E20.1 Pseudohypoparathyroidism
E20.8 Other hypoparathyroidism
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
