2023 ICD-10-CM Diagnosis Code E16.2

Hypoglycemia, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • E16.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM E16.2 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of E16.2 - other international versions of ICD-10 E16.2 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E16.2. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • diabetes with hypoglycemia (
    ICD-10-CM Diagnosis Code E08.649

    Diabetes mellitus due to underlying condition with hypoglycemia without coma

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Manifestation Code
    E08.649
    ,
    ICD-10-CM Diagnosis Code E10.649

    Type 1 diabetes mellitus with hypoglycemia without coma

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    E10.649
    ,
    ICD-10-CM Diagnosis Code E11.649

    Type 2 diabetes mellitus with hypoglycemia without coma

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    E11.649
    ,
    ICD-10-CM Diagnosis Code E13.649

    Other specified diabetes mellitus with hypoglycemia without coma

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    E13.649
    )
The following code(s) above E16.2 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E16.2:
  • E00-E89
    2023 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
Approximate Synonyms
  • Hypoglycemia
  • Hypoglycemia (low blood sugar)
  • Hypoglycemia post gi surgery
  • Hypoglycemia unawareness
  • Hypoglycemic encephalopathy
  • Loss of hypoglycemic warning
  • Post gastrointestinal tract surgery hypoglycemia
Clinical Information
  • A disorder characterized by laboratory test results that indicate a low concentration of glucose in the blood.
  • A syndrome of abnormally low blood glucose level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger; sweating; paresthesia; impaired mental function; seizures; coma; and even death.
  • Abnormally low blood sugar.
  • Abnormally low level of glucose in the blood.
  • Hypoglycemia means low blood glucose. Your body needs glucose, a form of sugar, to have enough energy. After you eat, your blood absorbs glucose. If you eat more sugar than your body needs, your muscles, and liver store the extra. When your blood sugar begins to fall, a hormone tells your liver to release glucose.in most people, this raises blood sugar. If it doesn't, you have hypoglycemia, and your blood sugar can be dangerously low. Signs include
    • hunger
    • shakiness
    • dizziness
    • confusion
    • difficulty speaking
    • feeling anxious or weak
    in people with diabetes, hypoglycemia is often a side effect of diabetes medicines. Eating or drinking something with carbohydrates can help. If it happens often, your health care provider may need to change your treatment plan.you can also have low blood sugar without having diabetes. Causes include certain medicines or diseases, hormone or enzyme deficiencies, and tumors. Laboratory tests can help find the cause. The kind of treatment depends on why you have low blood sugar.
  • Syndrome of abnormally low blood glucose level; clinical hypoglycemia has diverse etiologies; severe hypoglycemia eventually lead to glucose deprivation of the central nervous system resulting in hunger, sweating, paresthesia, impaired mental function, seizures, coma, and even death.
ICD-10-CM E16.2 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
  • 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc

Convert E16.2 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to E16.2:
  • Type 1 Excludes: R73.0
    , R79
    , E74
    , E89.1
    ICD-10-CM Diagnosis Code R73.0

    Abnormal glucose

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    ICD-10-CM Diagnosis Code R79

    Other abnormal findings of blood chemistry

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • asymptomatic hyperuricemia (E79.0)
    • hyperglycemia NOS (R73.9)
    • hypoglycemia NOS (E16.2)
    • neonatal hypoglycemia (P70.3-P70.4)
    • specific findings indicating disorder of amino-acid metabolism (E70-E72)
    • specific findings indicating disorder of carbohydrate metabolism (E73-E74)
    • specific findings indicating disorder of lipid metabolism (E75.-)
    Use Additional
    • code to identify any retained foreign body, if applicable (Z18.-)
    ICD-10-CM Diagnosis Code E74

    Other disorders of carbohydrate metabolism

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    ICD-10-CM Diagnosis Code E89.1

    Postprocedural hypoinsulinemia

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Postpancreatectomy hyperglycemia
    • Postsurgical hypoinsulinemia
    Type 1 Excludes
    • transient postprocedural hyperglycemia (R73.9)
    • transient postprocedural hypoglycemia (E16.2)
    Use Additional
    • code, if applicable, to identify:
    • acquired absence of pancreas (Z90.41-)
    • diabetes mellitus (postpancreatectomy) (postprocedural) (E13.-)
    • insulin use (Z79.4)

Diagnosis Index entries containing back-references to E16.2:
  • Encephalopathy (acute) G93.40
    ICD-10-CM Diagnosis Code G93.40

    Encephalopathy, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    • hypoglycemic E16.2
  • Findings, abnormal, inconclusive, without diagnosis - see also Abnormal
    • blood sugar R73.09
      ICD-10-CM Diagnosis Code R73.09

      Other abnormal glucose

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Abnormal glucose NOS
      • Abnormal non-fasting glucose tolerance
      • low E16.2 (transient)
  • Glycopenia E16.2
  • Hypoglycemia (spontaneous) E16.2
  • McQuarrie's syndrome E16.2 (idiopathic familial hypoglycemia)
  • Polyneuropathy (peripheral) G62.9
    ICD-10-CM Diagnosis Code G62.9

    Polyneuropathy, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Neuropathy NOS
    • in (due to)
      • hypoglycemia E16.2
  • Sugar
    • blood
      • low E16.2 (transient)
  • Syndrome - see also Disease
    • hypoglycemic E16.2 (familial) (neonatal)
    • McQuarrie's E16.2

ICD-10-CM Codes Adjacent To E16.2
E13.641 …… with coma
E13.649 …… without coma
E13.65 Other specified diabetes mellitus with hyperglycemia
E13.69 Other specified diabetes mellitus with other specified complication
E13.8 Other specified diabetes mellitus with unspecified complications
E13.9 Other specified diabetes mellitus without complications
E15 Nondiabetic hypoglycemic coma
E16 Other disorders of pancreatic internal secretion
E16.0 Drug-induced hypoglycemia without coma
E16.1 Other hypoglycemia
E16.2 Hypoglycemia, unspecified
E16.3 Increased secretion of glucagon
E16.4 Increased secretion of gastrin
E16.8 Other specified disorders of pancreatic internal secretion
E16.9 Disorder of pancreatic internal secretion, unspecified
E20 Hypoparathyroidism
E20.0 Idiopathic hypoparathyroidism
E20.1 Pseudohypoparathyroidism
E20.8 Other hypoparathyroidism
E20.9 Hypoparathyroidism, unspecified
E21 Hyperparathyroidism and other disorders of parathyroid gland

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.