2020 ICD-10-CM Diagnosis Code E21.1

Secondary hyperparathyroidism, not elsewhere classified

    2016 2017 2018 2019 2020 Billable/Specific Code
  • E21.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM E21.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E21.1 - other international versions of ICD-10 E21.1 may differ.
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E21.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • secondary hyperparathyroidism of renal origin (
    ICD-10-CM Diagnosis Code N25.81

    Secondary hyperparathyroidism of renal origin

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • secondary hyperparathyroidism, non-renal (E21.1)
    Type 2 Excludes
    • metabolic disorders classifiable to E70-E88
    N25.81
    )
The following code(s) above E21.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E21.1:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E20-E35
    2020 ICD-10-CM Range E20-E35

    Disorders of other endocrine glands

    Type 1 Excludes
    Disorders of other endocrine glands
  • E21
    ICD-10-CM Diagnosis Code E21

    Hyperparathyroidism and other disorders of parathyroid gland

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • adult osteomalacia (M83.-)
    • ectopic hyperparathyroidism (E34.2)
    • familial hypocalciuric hypercalcemia (E83.52)
    • hungry bone syndrome (E83.81)
    • infantile and juvenile osteomalacia (E55.0)
    Hyperparathyroidism and other disorders of parathyroid gland
Approximate Synonyms
  • Hyperparathyroidism, secondary (non renal)
  • Secondary hyperparathyroidism of nonrenal origin
ICD-10-CM E21.1 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E21.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to E21.1:
  • Type 1 Excludes: N25.81
    ICD-10-CM Diagnosis Code N25.81

    Secondary hyperparathyroidism of renal origin

      2016 2017 2018 2019 2020 Billable/Specific Code
    Type 1 Excludes
    • secondary hyperparathyroidism, non-renal (E21.1)
    Type 2 Excludes
    • metabolic disorders classifiable to E70-E88

Diagnosis Index entries containing back-references to E21.1:
  • Hyperparathyroidism E21.3
    ICD-10-CM Diagnosis Code E21.3

    Hyperparathyroidism, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • secondary (renal) N25.81
      ICD-10-CM Diagnosis Code N25.81

      Secondary hyperparathyroidism of renal origin

        2016 2017 2018 2019 2020 Billable/Specific Code
      Type 1 Excludes
      • secondary hyperparathyroidism, non-renal (E21.1)
      Type 2 Excludes
      • metabolic disorders classifiable to E70-E88
      • non-renal E21.1
  • Osteodystrophy Q78.9
    ICD-10-CM Diagnosis Code Q78.9

    Osteochondrodysplasia, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code POA Exempt
    Applicable To
    • Chondrodystrophy NOS
    • Osteodystrophy NOS
    • parathyroid, secondary E21.1

ICD-10-CM Codes Adjacent To E21.1
E16.4 Increased secretion of gastrin
E16.8 Other specified disorders of pancreatic internal secretion
E16.9 Disorder of pancreatic internal secretion, unspecified
E20 Hypoparathyroidism
E20.0 Idiopathic hypoparathyroidism
E20.1 Pseudohypoparathyroidism
E20.8 Other hypoparathyroidism
E20.9 Hypoparathyroidism, unspecified
E21 Hyperparathyroidism and other disorders of parathyroid gland
E21.0 Primary hyperparathyroidism
E21.1 Secondary hyperparathyroidism, not elsewhere classified
E21.2 Other hyperparathyroidism
E21.3 Hyperparathyroidism, unspecified
E21.4 Other specified disorders of parathyroid gland
E21.5 Disorder of parathyroid gland, unspecified
E22 Hyperfunction of pituitary gland
E22.0 Acromegaly and pituitary gigantism
E22.1 Hyperprolactinemia
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
E22.8 Other hyperfunction of pituitary gland
E22.9 Hyperfunction of pituitary gland, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.