ICD-10-CM Codes
E00-E89
E20-E35
E21-
2023 ICD-10-CM Diagnosis Code E21.1

2023 ICD-10-CM Diagnosis Code E21.1

Secondary hyperparathyroidism, not elsewhere classified

2016

2017

2018

2019

2020

2021

2022

2023

Billable/Specific Code

E21.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
The 2023 edition of ICD-10-CM E21.1 became effective on October 1, 2022.
This is the American ICD-10-CM version of E21.1 - other international versions of ICD-10 E21.1 may differ.

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E21.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

secondary hyperparathyroidism of renal origin (
ICD-10-CM Diagnosis Code N25.81
Secondary hyperparathyroidism of renal origin
Type 1 Excludes
- secondary hyperparathyroidism, non-renal (E21.1)
Type 2 Excludes
- metabolic disorders classifiable to E70-E88
N25.81
)

The following code(s) above E21.1 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to E21.1:

E00-E89
2023 ICD-10-CM Range E00-E89
Endocrine, nutritional and metabolic diseases
Note
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Type 1 Excludes
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Endocrine, nutritional and metabolic diseases
E20-E35
2023 ICD-10-CM Range E20-E35
Disorders of other endocrine glands
Type 1 Excludes
- galactorrhea (N64.3)
- gynecomastia (N62)
Disorders of other endocrine glands
E21
ICD-10-CM Diagnosis Code E21
Hyperparathyroidism and other disorders of parathyroid gland
Type 1 Excludes
- adult osteomalacia (M83.-)
- ectopic hyperparathyroidism (E34.2)
- hungry bone syndrome (E83.81)
- infantile and juvenile osteomalacia (E55.0)
Type 2 Excludes
- familial hypocalciuric hypercalcemia (E83.52)
Hyperparathyroidism and other disorders of parathyroid gland

Approximate Synonyms

Hyperparathyroidism, secondary (non renal)
Secondary hyperparathyroidism of nonrenal origin

ICD-10-CM E21.1 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):

643 Endocrine disorders with mcc
644 Endocrine disorders with cc
645 Endocrine disorders without cc/mcc

Convert E21.1 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

Code annotations containing back-references to E21.1:

Type 1 Excludes: N25.81

ICD-10-CM Diagnosis Code N25.81
Secondary hyperparathyroidism of renal origin
Type 1 Excludes
- secondary hyperparathyroidism, non-renal (E21.1)
Type 2 Excludes
- metabolic disorders classifiable to E70-E88

Diagnosis Index entries containing back-references to E21.1:

Hyperparathyroidism E21.3
ICD-10-CM Diagnosis Code E21.3
Hyperparathyroidism, unspecified
- secondary (renal) N25.81
  ICD-10-CM Diagnosis Code N25.81
  Secondary hyperparathyroidism of renal origin
  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  Type 1 Excludes
  secondary hyperparathyroidism, non-renal (E21.1)
  Type 2 Excludes
  metabolic disorders classifiable to E70-E88
  - non-renal E21.1
Osteodystrophy Q78.9
ICD-10-CM Diagnosis Code Q78.9
Osteochondrodysplasia, unspecified
Applicable To
Chondrodystrophy NOS
Osteodystrophy NOS
- parathyroid, secondary E21.1

ICD-10-CM Codes Adjacent To E21.1

E16.4 Increased secretion of gastrin

E16.8 Other specified disorders of pancreatic internal secretion

E16.9 Disorder of pancreatic internal secretion, unspecified

E20 Hypoparathyroidism

E20.0 Idiopathic hypoparathyroidism

E20.1 Pseudohypoparathyroidism

E20.8 Other hypoparathyroidism

E20.9 Hypoparathyroidism, unspecified

E21 Hyperparathyroidism and other disorders of parathyroid gland

E21.0 Primary hyperparathyroidism

E21.1 Secondary hyperparathyroidism, not elsewhere classified

E21.2 Other hyperparathyroidism

E21.3 Hyperparathyroidism, unspecified

E21.4 Other specified disorders of parathyroid gland

E21.5 Disorder of parathyroid gland, unspecified

E22 Hyperfunction of pituitary gland

E22.0 Acromegaly and pituitary gigantism

E22.1 Hyperprolactinemia

E22.2 Syndrome of inappropriate secretion of antidiuretic hormone

E22.8 Other hyperfunction of pituitary gland

E22.9 Hyperfunction of pituitary gland, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code E21.1

Secondary hyperparathyroidism, not elsewhere classified

Secondary hyperparathyroidism of renal origin

Endocrine, nutritional and metabolic diseases

Disorders of other endocrine glands

Hyperparathyroidism and other disorders of parathyroid gland

Secondary hyperparathyroidism of renal origin

Hyperparathyroidism, unspecified

Secondary hyperparathyroidism of renal origin

Osteochondrodysplasia, unspecified