2020 ICD-10-CM Diagnosis Code E21.5

Disorder of parathyroid gland, unspecified

    2016 2017 2018 2019 2020 Billable/Specific Code
  • E21.5 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM E21.5 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E21.5 - other international versions of ICD-10 E21.5 may differ.
The following code(s) above E21.5 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E21.5:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E20-E35
    2020 ICD-10-CM Range E20-E35

    Disorders of other endocrine glands

    Type 1 Excludes
    Disorders of other endocrine glands
  • E21
    ICD-10-CM Diagnosis Code E21

    Hyperparathyroidism and other disorders of parathyroid gland

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • adult osteomalacia (M83.-)
    • ectopic hyperparathyroidism (E34.2)
    • familial hypocalciuric hypercalcemia (E83.52)
    • hungry bone syndrome (E83.81)
    • infantile and juvenile osteomalacia (E55.0)
    Hyperparathyroidism and other disorders of parathyroid gland
Approximate Synonyms
  • Disorder of parathyroid gland
  • Parathyroid disorder
Clinical Information
  • Deviation from or interruption of the normal structure or function of the parathyroid gland.
  • Most people have four pea-sized glands, called parathyroid glands, on the thyroid gland in the neck. Though their names are similar, the thyroid and parathyroid glands are completely different. The parathyroid glands make parathyroid hormone (pth), which helps your body keep the right balance of calcium and phosphorous. If your parathyroid glands make too much or too little hormone, it disrupts this balance. If they secrete extra pth, you have hyperparathyroidism, and your blood calcium rises. In many cases, a benign tumor on a parathyroid gland makes it overactive. Or, the extra hormones can come from enlarged parathyroid glands. Very rarely, the cause is cancer.if you do not have enough pth, you have hypoparathyroidism. Your blood will have too little calcium and too much phosphorous. Causes include injury to the glands, endocrine disorders, or genetic conditions. Treatment is aimed at restoring the balance of calcium and phosphorous.
  • Pathological processes of the parathyroid glands. They usually manifest as hypersecretion or hyposecretion of parathyroid hormone that regulates the balance of calcium; phosphorus; and magnesium in the body.
ICD-10-CM E21.5 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E21.5 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to E21.5:

ICD-10-CM Codes Adjacent To E21.5
E20.0 Idiopathic hypoparathyroidism
E20.1 Pseudohypoparathyroidism
E20.8 Other hypoparathyroidism
E20.9 Hypoparathyroidism, unspecified
E21 Hyperparathyroidism and other disorders of parathyroid gland
E21.0 Primary hyperparathyroidism
E21.1 Secondary hyperparathyroidism, not elsewhere classified
E21.2 Other hyperparathyroidism
E21.3 Hyperparathyroidism, unspecified
E21.4 Other specified disorders of parathyroid gland
E21.5 Disorder of parathyroid gland, unspecified
E22 Hyperfunction of pituitary gland
E22.0 Acromegaly and pituitary gigantism
E22.1 Hyperprolactinemia
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
E22.8 Other hyperfunction of pituitary gland
E22.9 Hyperfunction of pituitary gland, unspecified
E23 Hypofunction and other disorders of the pituitary gland
E23.0 Hypopituitarism
E23.1 Drug-induced hypopituitarism
E23.2 Diabetes insipidus

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.