ICD-10-CM Codes
E00-E89
E20-E35
E22-
2023 ICD-10-CM Diagnosis Code E22

2023 ICD-10-CM Diagnosis Code E22

Hyperfunction of pituitary gland

2016

2017

2018

2019

2020

2021

2022

2023

Non-Billable/Non-Specific Code

E22 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
The 2023 edition of ICD-10-CM E22 became effective on October 1, 2022.
This is the American ICD-10-CM version of E22 - other international versions of ICD-10 E22 may differ.

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E22. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

Cushing's syndrome (
ICD-10-CM Diagnosis Code E24
- E24 Cushing's syndrome
  - E24.0 Pituitary-dependent Cushing's disease
  - E24.1 Nelson's syndrome
  - E24.2 Drug-induced Cushing's syndrome
  - E24.3 Ectopic ACTH syndrome
  - E24.4 Alcohol-induced pseudo-Cushing's syndrome
  - E24.8 Other Cushing's syndrome
  - E24.9 Cushing's syndrome, unspecified
E24.-
)
Nelson's syndrome (
ICD-10-CM Diagnosis Code E24.1
Nelson's syndrome
E24.1
)
overproduction of ACTH not associated with Cushing's disease (
ICD-10-CM Diagnosis Code E27.0
Other adrenocortical overactivity
Applicable To
- Overproduction of ACTH, not associated with Cushing's disease
- Premature adrenarche
Type 1 Excludes
- Cushing's syndrome (E24.-)
E27.0
)
overproduction of pituitary ACTH (
ICD-10-CM Diagnosis Code E24.0
Pituitary-dependent Cushing's disease
Applicable To
- Overproduction of pituitary ACTH
- Pituitary-dependent hypercorticalism
E24.0
)
overproduction of thyroid-stimulating hormone (
ICD-10-CM Diagnosis Code E05.8
Other thyrotoxicosis
Applicable To
- Overproduction of thyroid-stimulating hormone
E05.8-
)

The following code(s) above E22 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to E22:

E00-E89
2023 ICD-10-CM Range E00-E89
Endocrine, nutritional and metabolic diseases
Note
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Type 1 Excludes
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Endocrine, nutritional and metabolic diseases
E20-E35
2023 ICD-10-CM Range E20-E35
Disorders of other endocrine glands
Type 1 Excludes
- galactorrhea (N64.3)
- gynecomastia (N62)
Disorders of other endocrine glands

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

ICD-10-CM Codes Adjacent To E22

E20.1 Pseudohypoparathyroidism

E20.8 Other hypoparathyroidism

E20.9 Hypoparathyroidism, unspecified

E21 Hyperparathyroidism and other disorders of parathyroid gland

E21.0 Primary hyperparathyroidism

E21.1 Secondary hyperparathyroidism, not elsewhere classified

E21.2 Other hyperparathyroidism

E21.3 Hyperparathyroidism, unspecified

E21.4 Other specified disorders of parathyroid gland

E21.5 Disorder of parathyroid gland, unspecified

E22 Hyperfunction of pituitary gland

E22.0 Acromegaly and pituitary gigantism

E22.1 Hyperprolactinemia

E22.2 Syndrome of inappropriate secretion of antidiuretic hormone

E22.8 Other hyperfunction of pituitary gland

E22.9 Hyperfunction of pituitary gland, unspecified

E23 Hypofunction and other disorders of the pituitary gland

E23.0 Hypopituitarism

E23.1 Drug-induced hypopituitarism

E23.2 Diabetes insipidus

E23.3 Hypothalamic dysfunction, not elsewhere classified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code E22

Hyperfunction of pituitary gland

Nelson's syndrome

Other adrenocortical overactivity

Pituitary-dependent Cushing's disease

Other thyrotoxicosis

Endocrine, nutritional and metabolic diseases

Disorders of other endocrine glands