2019 ICD-10-CM Diagnosis Code E22.0

Acromegaly and pituitary gigantism

    2016 2017 2018 2019 Billable/Specific Code
  • E22.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM E22.0 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of E22.0 - other international versions of ICD-10 E22.0 may differ.
Applicable To
  • Overproduction of growth hormone
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E22.0. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • constitutional gigantism (
    ICD-10-CM Diagnosis Code E34.4

    Constitutional tall stature

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Constitutional gigantism
    E34.4
    )
  • constitutional tall stature (
    ICD-10-CM Diagnosis Code E34.4

    Constitutional tall stature

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Constitutional gigantism
    E34.4
    )
  • increased secretion from endocrine pancreas of growth hormone-releasing hormone (
    ICD-10-CM Diagnosis Code E16.8

    Other specified disorders of pancreatic internal secretion

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Increased secretion from endocrine pancreas of growth hormone-releasing hormone
    • Increased secretion from endocrine pancreas of pancreatic polypeptide
    • Increased secretion from endocrine pancreas of somatostatin
    • Increased secretion from endocrine pancreas of vasoactive-intestinal polypeptide
    E16.8
    )
The following code(s) above E22.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E22.0:
  • E00-E89
    2019 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E20-E35
    2019 ICD-10-CM Range E20-E35

    Disorders of other endocrine glands

    Type 1 Excludes
    Disorders of other endocrine glands
  • E22
    ICD-10-CM Diagnosis Code E22

    Hyperfunction of pituitary gland

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • Cushing's syndrome (E24.-)
    • Nelson's syndrome (E24.1)
    • overproduction of ACTH not associated with Cushing's disease (E27.0)
    • overproduction of pituitary ACTH (E24.0)
    • overproduction of thyroid-stimulating hormone (E05.8-)
    Hyperfunction of pituitary gland
Approximate Synonyms
  • Acromegaly
  • Growth hormone overproduction
  • Hypersomatotropic gigantism
  • Overproduction of growth hormone
  • Pituitary gigantism
  • Sotos syndrome
  • Sotos' syndrome
ICD-10-CM E22.0 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E22.0 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to E22.0:
  • Type 1 Excludes: M26.0
    ICD-10-CM Diagnosis Code M26.0

    Major anomalies of jaw size

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes

Diagnosis Index entries containing back-references to E22.0:
  • Acromegaly, acromegalia E22.0
  • Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) M19.90
    ICD-10-CM Diagnosis Code M19.90

    Unspecified osteoarthritis, unspecified site

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Arthrosis NOS
    • Arthritis NOS
    • Osteoarthritis NOS
  • Arthropathy M12.9
    - see also Arthritis
    ICD-10-CM Diagnosis Code M12.9

    Arthropathy, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    • in (due to)
      • acromegaly E22.0
  • Erdheim's syndrome E22.0 (acromegalic macrospondylitis)
  • Gigantism (cerebral) (hypophyseal) (pituitary) E22.0
  • Hypersecretion
  • Hypophyseal, hypophysis - see also condition
    • gigantism E22.0
  • Launois' syndrome E22.0 (pituitary gigantism)
  • Macrospondylitis , acromegalic E22.0
  • Marie's
    • disease or syndrome E22.0 (acromegaly)
  • Overproduction - see also Hypersecretion
    • growth hormone E22.0
  • Scaglietti-Dagnini syndrome E22.0
  • Syndrome - see also Disease
    • cerebral
      • gigantism E22.0
    • costovertebral E22.0
    • Erdheim's E22.0
    • Launois' E22.0
    • Marie's E22.0 (acromegaly)
    • pituitary E22.0
    • Scaglietti-Dagnini E22.0

ICD-10-CM Codes Adjacent To E22.0
E20.8 Other hypoparathyroidism
E20.9 Hypoparathyroidism, unspecified
E21 Hyperparathyroidism and other disorders of parathyroid gland
E21.0 Primary hyperparathyroidism
E21.1 Secondary hyperparathyroidism, not elsewhere classified
E21.2 Other hyperparathyroidism
E21.3 Hyperparathyroidism, unspecified
E21.4 Other specified disorders of parathyroid gland
E21.5 Disorder of parathyroid gland, unspecified
E22 Hyperfunction of pituitary gland
E22.0 Acromegaly and pituitary gigantism
E22.1 Hyperprolactinemia
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
E22.8 Other hyperfunction of pituitary gland
E22.9 Hyperfunction of pituitary gland, unspecified
E23 Hypofunction and other disorders of the pituitary gland
E23.0 Hypopituitarism
E23.1 Drug-induced hypopituitarism
E23.2 Diabetes insipidus
E23.3 Hypothalamic dysfunction, not elsewhere classified
E23.6 Other disorders of pituitary gland

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.