1. ICD-10-CM Codes
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2. E00-E89
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3. E20-E35
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4. E23-
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5. 2023 ICD-10-CM Diagnosis Code E23.0

2023 ICD-10-CM Diagnosis Code E23.0

Hypopituitarism

2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

• E23.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2023 edition of ICD-10-CM E23.0 became effective on October 1, 2022.
• This is the American ICD-10-CM version of E23.0 - other international versions of ICD-10 E23.0 may differ.

• Anterior pituitary hormone deficiency
• Female infertility due to pituitary disorder
• Female infertility of pituitary origin
• Follicle stimulating hormone deficiency
• Fsh - follicle stimulating hormone deficiency
• Gonadotropin deficiency, isolated
• Growth hormone deficiency
• Growth hormone deficiency after bone marrow transplant
• Growth hormone deficiency, bone marrow transplant
• Growth hormone deficiency, isolated
• Hypogonadism with anosmia
• Hypogonadism, anosmia
• Hypogonadotropic hypogonadism
• Isolated gonadotropin deficiency
• Isolated somatotropin deficiency
• Lh - luteinizing hormone deficiency
• Luteinizing hormone deficiency
• Panhypopituitarism
• Partial growth hormone deficiency
• Partial hypopituitarism
• Pituitary dwarfism
• Somatotropin deficiency, partial

• A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.
• A form of dwarfism caused by complete or partial growth hormone deficiency, resulting from either the lack of growth hormone-releasing factor from the hypothalamus or from the mutations in the growth hormone gene (gh1) in the pituitary gland. It is also known as type i pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of human growth hormone during development.
• A genetically heterogeneous disorder caused by hypothalamic gnrh deficiency and olfactory nerve defects. It is characterized by congenital hypogonadotropic hypogonadism and anosmia, possibly with additional midline defects. It can be transmitted as an x-linked (genetic diseases, x-linked), an autosomal dominant, or an autosomal recessive trait.
• A syndrome, sometimes considered as three separate entities (kalmann syndromes 1, 2, and 3), characterized mainly by reduced hypothalamic function and reduced pituitary gonadotropic activity and deficiency of gonadotropin-releasing hormone with resulting hypogonadism and absent or reduced sense of smell due to agenesis of the olfactory bulbs. Associated anomalies include cleft palate, neurosensory hearing loss, congenital heart defect, intestinal malrotation, renal agenesis, hypertension, mental retardation, color blindness, and other defects. Most abnormalities occur in types 1 and 2; type 3 is marked mainly by hypogonadotropic hypogonadism, anosmia, and craniofacial abnormalities.
• An x-linked or autosomal dominant genetic syndrome characterized by hypogonadotropic hypogonadism and anosmia.
• Anosmia due to failure of the olfactory lobes to develop, with secondary hypogonadism due to gonadotropic hormone deficiency.
• Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including lh; follicle stimulating hormone; somatotropin; and corticotropin). This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.
• Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including luteinizing hormone, follicle stimulating hormone, somatotropin; and corticotropin); may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.
• Form of dwarfism due to deficient release of growth hormone which may result from dysfunction of the hypothalamus or anterior pituitary gland.

• 643 Endocrine disorders with mcc
• 644 Endocrine disorders with cc
• 645 Endocrine disorders without cc/mcc

Convert E23.0 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Type 1 Excludes: R62
  , E28
  , E34.3
  , E29
  ICD-10-CM Diagnosis Code R62

  Lack of expected normal physiological development in childhood and adults

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • delayed puberty (E30.0)
  • gonadal dysgenesis (Q99.1)
  • hypopituitarism (E23.0)
  ICD-10-CM Diagnosis Code E28

  Ovarian dysfunction

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • isolated gonadotropin deficiency (E23.0)
  • postprocedural ovarian failure (E89.4-)
  ICD-10-CM Diagnosis Code E34.3

  Short stature due to endocrine disorder

  2016 2017 2018 2019 2020 2021 2022 2023 - Converted to Parent Code Non-Billable/Non-Specific Code

  Type 1 Excludes

  • achondroplastic short stature (Q77.4)
  • hypochondroplastic short stature (Q77.4)
  • nutritional short stature (E45)
  • pituitary short stature (E23.0)
  • progeria (E34.8)
  • renal short stature (N25.0)
  • Russell-Silver syndrome (Q87.19)
  • short-limbed stature with immunodeficiency (D82.2)
  • short stature (child) (R62.52)
  • short stature in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index
  • short stature NOS (R62.52)
  ICD-10-CM Diagnosis Code E29

  Testicular dysfunction

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Type 1 Excludes

  • androgen insensitivity syndrome (E34.5-)
  • azoospermia or oligospermia NOS (N46.0-N46.1)
  • isolated gonadotropin deficiency (E23.0)
  • Klinefelter's syndrome (Q98.0-Q98.1, Q98.4)
• Type 2 Excludes: N97
  ICD-10-CM Diagnosis Code N97

  Female infertility

  2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code

  Includes

  • inability to achieve a pregnancy
  • sterility, female NOS

  Type 2 Excludes

  • female infertility associated with:
  • hypopituitarism (E23.0)
  • Stein-Leventhal syndrome (E28.2)
  • incompetence of cervix uteri (N88.3)

• Ahumada-del Castillo syndrome E23.0
• Brissaud's
  • infantilism or dwarfism E23.0
• Cachexia R64
  ICD-10-CM Diagnosis Code R64

  Cachexia

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Wasting syndrome

  Code First

  • underlying condition, if known

  Type 1 Excludes

  • abnormal weight loss (R63.4)
  • nutritional marasmus (E41)
  • hypophyseal E23.0
  • hypopituitary E23.0
  • pituitary E23.0
  • Simmonds' E23.0
• Decrease (d)
  • function
    • pituitary (gland) (anterior) (lobe) E23.0
      • posterior E23.0 (lobe)
    • ovary in hypopituitarism E23.0
• Deficiency, deficient
  • hormone
    • anterior pituitary (partial) E23.0
      • growth E23.0
    • growth E23.0 (isolated)
    • pituitary E23.0
  • gonadotropin E23.0 (isolated)
  • growth hormone E23.0 (idiopathic) (isolated)
  • pituitary hormone E23.0 (isolated)
• Dwarfism E34.328
  - see also Stature, short
  ICD-10-CM Diagnosis Code E34.328

  Other genetic causes of short stature

  2023 - New Code Billable/Specific Code

  Applicable To

  • Short stature due to ACAN gene variant
  • Short stature due to aggrecan deficiency
  • Short stature due to NPR-2 gene variant
  • hypophyseal E23.0
  • Lorain E23.0 (-Levi)
  • pituitary E23.0
• Eunuchoidism E29.1
  ICD-10-CM Diagnosis Code E29.1

  Testicular hypofunction

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Male Dx

  Applicable To

  • Defective biosynthesis of testicular androgen NOS
  • 5-delta-Reductase deficiency (with male pseudohermaphroditism)
  • Testicular hypogonadism NOS

  Type 1 Excludes

  • postprocedural testicular hypofunction (E89.5)

  Use Additional

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • hypogonadotropic E23.0
• Fertile eunuch syndrome E23.0
• Hypoadrenocorticism E27.40
  ICD-10-CM Diagnosis Code E27.40

  Unspecified adrenocortical insufficiency

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Adrenocortical insufficiency NOS
  • Hypoaldosteronism
  • pituitary E23.0
• Hypofunction
  • pituitary E23.0 (gland) (anterior)
• Hypogonadism
  • hypogonadotropic E23.0
  • pituitary E23.0
• Hypophyseal, hypophysis - see also condition
  • dwarfism E23.0
• Hypopituitarism (juvenile) E23.0
• Hyposecretion
  • ACTH E23.0
• Infancy, infantile, infantilism - see also condition
  • Lorain E23.0
  • pituitary E23.0
• Infertility
  • female N97.9
    ICD-10-CM Diagnosis Code N97.9

    Female infertility, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Female Dx
    • associated with
      • pituitary-hypothalamic origin E23.0
• Insufficiency, insufficient
  • pituitary E23.0
• Kallmann's syndrome E23.0
• Lorain E23.0 (-Levi)
• Myopathy G72.9
  ICD-10-CM Diagnosis Code G72.9

  Myopathy, unspecified

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • in (due to)
    • hypopituitarism E23.0
• Necrosis, necrotic (ischemic) - see also Gangrene
  • pituitary (gland) E23.0
• Panhypopituitarism E23.0
  • prepubertal E23.0
• Sheehan's disease or syndrome E23.0
• Simmonds' cachexia or disease E23.0
• Syndrome - see also Disease
  • fertile eunuch E23.0
  • hypopituitarism E23.0
  • infantilism E23.0 (pituitary)
  • postpartum panhypopituitary E23.0 (Sheehan)

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.