1. ICD-10-CM Codes
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2. E00-E89
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3. E20-E35
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4. E27-
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5. 2023 ICD-10-CM Diagnosis Code E27.1

2023 ICD-10-CM Diagnosis Code E27.1

Primary adrenocortical insufficiency

2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

• E27.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2023 edition of ICD-10-CM E27.1 became effective on October 1, 2022.
• This is the American ICD-10-CM version of E27.1 - other international versions of ICD-10 E27.1 may differ.

• Addison's disease
• Addison's disease, myopathy
• Adrenal calcification
• Adrenal insufficiency, primary
• Myopathy in addison's disease

• A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of acth from the pituitary.
• A rare endocrine or hormonal disorder that occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal glands themselves (primary adrenal insufficiency) or to inadequate secretion of acth by the pituitary gland (secondary adrenal insufficiency).
• An adrenal disease characterized by the progressive destruction of the adrenal cortex, resulting in insufficient production of aldosterone and hydrocortisone. Clinical symptoms include anorexia; nausea; weight loss; muscle weakness; and hyperpigmentation of the skin due to increase in circulating levels of acth precursor hormone which stimulates melanocytes.
• Disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin; due to tuberculosis or autoimmune induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol.
• Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison's disease happens if the adrenal glands don't make enough of these hormones. A problem with your immune system usually causes addison's disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer. Symptoms include
  • weight loss
  • muscle weakness
  • fatigue that gets worse over time
  • low blood pressure
  • patchy or dark skin
  lab tests can confirm that you have addison's disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have addison's disease, you should carry an emergency id. It should say that you have the disease, list your medicines and say how much you need in an emergency.

• 643 Endocrine disorders with mcc
• 644 Endocrine disorders with cc
• 645 Endocrine disorders without cc/mcc

Convert E27.1 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Addison's
  • disease (bronze) E27.1
• Adrenalitis, adrenitis E27.8
  ICD-10-CM Diagnosis Code E27.8

  Other specified disorders of adrenal gland

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Abnormality of cortisol-binding globulin
  • autoimmune E27.1
• Atrophy, atrophic (of)
  • adrenal (capsule) (gland) E27.49
    ICD-10-CM Diagnosis Code E27.49

    Other adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenal hemorrhage
    • Adrenal infarction
    • primary E27.1 (autoimmune)
  • suprarenal (capsule) (gland) E27.49
    ICD-10-CM Diagnosis Code E27.49

    Other adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenal hemorrhage
    • Adrenal infarction
    • primary E27.1
• Deficiency, deficient
  • corticoadrenal E27.40
    ICD-10-CM Diagnosis Code E27.40

    Unspecified adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
    • primary E27.1
• Disease, diseased - see also Syndrome
  • bronze Addison's E27.1
• Hypoadrenalism, hypoadrenia E27.40
  ICD-10-CM Diagnosis Code E27.40

  Unspecified adrenocortical insufficiency

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Adrenocortical insufficiency NOS
  • Hypoaldosteronism
  • primary E27.1
• Hypoadrenocorticism E27.40
  ICD-10-CM Diagnosis Code E27.40

  Unspecified adrenocortical insufficiency

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Adrenocortical insufficiency NOS
  • Hypoaldosteronism
  • primary E27.1
• Hypofunction
  • adrenocortical E27.40
    ICD-10-CM Diagnosis Code E27.40

    Unspecified adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
    • primary E27.1
• Insufficiency, insufficient
  • adrenal (gland) E27.40
    ICD-10-CM Diagnosis Code E27.40

    Unspecified adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
    • primary E27.1
  • adrenocortical E27.40
    ICD-10-CM Diagnosis Code E27.40

    Unspecified adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
    • primary E27.1
  • corticoadrenal E27.40
    ICD-10-CM Diagnosis Code E27.40

    Unspecified adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
    • primary E27.1
  • suprarenal E27.40
    ICD-10-CM Diagnosis Code E27.40

    Unspecified adrenocortical insufficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
    • primary E27.1
• Melanosis L81.4
  ICD-10-CM Diagnosis Code L81.4

  Other melanin hyperpigmentation

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

  Applicable To

  • Lentigo
  • addisonian E27.1
  • adrenal E27.1
  • suprarenal E27.1
• Melasma L81.1
  ICD-10-CM Diagnosis Code L81.1

  Chloasma

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • adrenal E27.1 (gland)
  • suprarenal E27.1 (gland)
• Myopathy G72.9
  ICD-10-CM Diagnosis Code G72.9

  Myopathy, unspecified

  2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • in (due to)
    • Addison's disease E27.1

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.