ICD-10-CM Codes
E00-E89
E20-E35
E28-
2023 ICD-10-CM Diagnosis Code E28.31

2023 ICD-10-CM Diagnosis Code E28.31

Premature menopause

2016

2017

2018

2019

2020

2021

2022

2023

Non-Billable/Non-Specific Code

E28.31 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
The 2023 edition of ICD-10-CM E28.31 became effective on October 1, 2022.
This is the American ICD-10-CM version of E28.31 - other international versions of ICD-10 E28.31 may differ.

The following code(s) above E28.31 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to E28.31:

E00-E89
2023 ICD-10-CM Range E00-E89
Endocrine, nutritional and metabolic diseases
Note
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Type 1 Excludes
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Endocrine, nutritional and metabolic diseases
E20-E35
2023 ICD-10-CM Range E20-E35
Disorders of other endocrine glands
Type 1 Excludes
- galactorrhea (N64.3)
- gynecomastia (N62)
Disorders of other endocrine glands
E28
ICD-10-CM Diagnosis Code E28
Ovarian dysfunction
Type 1 Excludes
- isolated gonadotropin deficiency (E23.0)
- postprocedural ovarian failure (E89.4-)
Ovarian dysfunction
E28.3
ICD-10-CM Diagnosis Code E28.3
Primary ovarian failure
Type 1 Excludes
- pure gonadal dysgenesis (Q99.1)
- Turner's syndrome (Q96.-)
Primary ovarian failure

Clinical Information

A condition in which the ovaries stop working and menstrual periods stop before age 40. Natural menopause usually occurs around age 50. A woman is said to be in menopause when she hasn't had a period for 12 months in a row. Symptoms of menopause include hot flashes, mood swings, night sweats, vaginal dryness, trouble concentrating, and infertility. Premature menopause can be caused by some cancer treatments, surgery to remove the ovaries, and certain diseases or genetic conditions.
A disorder characterized by ovarian failure before the age of 40. Symptoms include hot flashes, night sweats, mood swings and a decrease in sex drive.
Ovarian failure before the age of 40. Symptoms include hot flashes, night sweats, mood swings, and decreased sex drive.
The premature cessation of menses (menstruation) when the last menstrual period occurs in a woman under the age of 40. It is due to the depletion of ovarian follicles. Premature menopause can be caused by diseases; ovariectomy; radiation; chemicals; and chromosomal abnormalities.

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change

Code annotations containing back-references to E28.31:

Type 1 Excludes: N95
, N95

ICD-10-CM Diagnosis Code N95
Menopausal and other perimenopausal disorders
Applicable To
- Menopausal and other perimenopausal disorders due to naturally occurring (age-related) menopause and perimenopause
Type 1 Excludes
- excessive bleeding in the premenopausal period (N92.4)
- menopausal and perimenopausal disorders due to artificial or premature menopause (E89.4-, E28.31-)
- premature menopause (E28.31-)
Type 2 Excludes
- postmenopausal osteoporosis (M81.0-)
- postmenopausal osteoporosis with current pathological fracture (M80.0-)
- postmenopausal urethritis (N34.2)
ICD-10-CM Diagnosis Code N95
Menopausal and other perimenopausal disorders
Applicable To
- Menopausal and other perimenopausal disorders due to naturally occurring (age-related) menopause and perimenopause
Type 1 Excludes
- excessive bleeding in the premenopausal period (N92.4)
- menopausal and perimenopausal disorders due to artificial or premature menopause (E89.4-, E28.31-)
- premature menopause (E28.31-)
Type 2 Excludes
- postmenopausal osteoporosis (M81.0-)
- postmenopausal osteoporosis with current pathological fracture (M80.0-)
- postmenopausal urethritis (N34.2)

ICD-10-CM Codes Adjacent To E28.31

E27.40 Unspecified adrenocortical insufficiency

E27.49 Other adrenocortical insufficiency

E27.5 Adrenomedullary hyperfunction

E27.8 Other specified disorders of adrenal gland

E27.9 Disorder of adrenal gland, unspecified

E28 Ovarian dysfunction

E28.0 Estrogen excess

E28.1 Androgen excess

E28.2 Polycystic ovarian syndrome

E28.3 Primary ovarian failure

E28.31 Premature menopause

E28.310 Symptomatic premature menopause

E28.319 Asymptomatic premature menopause

E28.39 Other primary ovarian failure

E28.8 Other ovarian dysfunction

E28.9 Ovarian dysfunction, unspecified

E29 Testicular dysfunction

E29.0 Testicular hyperfunction

E29.1 Testicular hypofunction

E29.8 Other testicular dysfunction

E29.9 Testicular dysfunction, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

2023 ICD-10-CM Diagnosis Code E28.31

Premature menopause

Endocrine, nutritional and metabolic diseases

Disorders of other endocrine glands

Ovarian dysfunction

Primary ovarian failure

Menopausal and other perimenopausal disorders

Menopausal and other perimenopausal disorders