2019 ICD-10-CM Diagnosis Code E31.0

Autoimmune polyglandular failure

    2016 2017 2018 2019 Billable/Specific Code
  • E31.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM E31.0 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of E31.0 - other international versions of ICD-10 E31.0 may differ.
Applicable To
  • Schmidt's syndrome
The following code(s) above E31.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E31.0:
  • E00-E89
    2019 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E20-E35
    2019 ICD-10-CM Range E20-E35

    Disorders of other endocrine glands

    Type 1 Excludes
    Disorders of other endocrine glands
  • E31
    ICD-10-CM Diagnosis Code E31

    Polyglandular dysfunction

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • ataxia telangiectasia [Louis-Bar] (G11.3)
    • dystrophia myotonica [Steinert] (G71.11)
    • pseudohypoparathyroidism (E20.1)
    Polyglandular dysfunction
Approximate Synonyms
  • Autoimmune polyendocrinopathy
  • Lloyd syndrome
  • Polyglandular autoimmune syndrome, type 2
  • Schmidts syndrome
Clinical Information
  • A rare genetic syndrome characterized by autoantibodies production against more than one endocrine organ. The range of endocrinopathies includes hypoparathyroidism, adrenal insufficiency, hypogonadism, type 1 diabetes mellitus and hypothyroidism.
  • An autoimmune diseases affecting multiple endocrine organs
  • Autoimmune diseases affecting multiple endocrine organs. Type i is characterized by childhood onset and chronic mucocutaneous candidiasis (candidiasis, chronic mucocutaneous), while type ii exhibits any combination of adrenal insufficiency (addison's disease), lymphocytic thyroiditis (thyroiditis, autoimmune;), hypoparathyroidism; and gonadal failure. In both types organ-specific antibodies against a variety of endocrine glands have been detected. The type ii syndrome differs from type i in that it is associated with hla-a1 and b8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
ICD-10-CM E31.0 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E31.0 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change

Diagnosis Index entries containing back-references to E31.0:
  • Atrophy, atrophic (of)
    • pluriglandular E31.8
      ICD-10-CM Diagnosis Code E31.8

      Other polyglandular dysfunction

        2016 2017 2018 2019 Billable/Specific Code
      • autoimmune E31.0
  • Deficiency, deficient
    • polyglandular E31.8
      ICD-10-CM Diagnosis Code E31.8

      Other polyglandular dysfunction

        2016 2017 2018 2019 Billable/Specific Code
      • autoimmune E31.0
  • Failure, failed
    • polyglandular, autoimmune E31.0
  • Insufficiency, insufficient
    • progressive pluriglandular E31.0
  • Polyglandular
    • deficiency E31.0
  • Schmidt's syndrome E31.0 (polyglandular, autoimmune)
  • Syndrome - see also Disease
    • pluriglandular (compensatory) E31.8
      ICD-10-CM Diagnosis Code E31.8

      Other polyglandular dysfunction

        2016 2017 2018 2019 Billable/Specific Code
      • autoimmune E31.0
    • polyglandular E31.8
      ICD-10-CM Diagnosis Code E31.8

      Other polyglandular dysfunction

        2016 2017 2018 2019 Billable/Specific Code
      • autoimmune E31.0
    • autoimmune polyglandular E31.0
    • thyroid-adrenocortical insufficiency E31.0

ICD-10-CM Codes Adjacent To E31.0
E29.0 Testicular hyperfunction
E29.1 Testicular hypofunction
E29.8 Other testicular dysfunction
E29.9 Testicular dysfunction, unspecified
E30 Disorders of puberty, not elsewhere classified
E30.0 Delayed puberty
E30.1 Precocious puberty
E30.8 Other disorders of puberty
E30.9 Disorder of puberty, unspecified
E31 Polyglandular dysfunction
E31.0 Autoimmune polyglandular failure
E31.1 Polyglandular hyperfunction
E31.2 Multiple endocrine neoplasia [MEN] syndromes
E31.20 Multiple endocrine neoplasia [MEN] syndrome, unspecified
E31.21 Multiple endocrine neoplasia [MEN] type I
E31.22 Multiple endocrine neoplasia [MEN] type IIA
E31.23 Multiple endocrine neoplasia [MEN] type IIB
E31.8 Other polyglandular dysfunction
E31.9 Polyglandular dysfunction, unspecified
E32 Diseases of thymus
E32.0 Persistent hyperplasia of thymus

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.