1. ICD-10-CM Codes
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2. E00-E89
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3. E20-E35
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4. E31-
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5. 2023 ICD-10-CM Diagnosis Code E31.22

2023 ICD-10-CM Diagnosis Code E31.22

Multiple endocrine neoplasia [MEN] type IIA

2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

• E31.22 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2023 edition of ICD-10-CM E31.22 became effective on October 1, 2022.
• This is the American ICD-10-CM version of E31.22 - other international versions of ICD-10 E31.22 may differ.

• Multiple endocrine neoplasia type 2a
• Multiple endocrine neoplasia type 2a cancerous
• Multiple endocrine neoplasia type 2a noncancerous
• Multiple endocrine neoplasia type 2a, benign
• Multiple endocrine neoplasia type 2a, malignant
• Multiple endocrine neoplasia, type 2

• A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (carcinoma, medullary) of the thyroid gland, and usually with the co-occurrence of pheochromocytoma, producing calcitonin and adrenaline, respectively. Less frequently, it can occur with hyperplasia or adenoma of the parathyroid glands. This disease is due to gain-of-function mutations of the men2 gene on chromosome 10 (locus: 10q11.2), also known as the ret proto-oncogene that encodes a receptor protein-tyrosine kinase. It is an autosomal dominant inherited disease.
• Multiple endocrine neoplasia caused by mutation of the ret gene. Patients develop medullary thyroid carcinomas, and may also develop pheochromocytomas and parathyroid gland hyperplasia.

• 643 Endocrine disorders with mcc
• 644 Endocrine disorders with cc
• 645 Endocrine disorders without cc/mcc

Convert E31.22 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change
• 2022 (effective 10/1/2021): No change
• 2023 (effective 10/1/2022): No change

• Neoplasia
  • endocrine, multiple (MEN) E31.20
    ICD-10-CM Diagnosis Code E31.20

    Multiple endocrine neoplasia [MEN] syndrome, unspecified

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code

    Applicable To

    • Multiple endocrine adenomatosis NOS
    • Multiple endocrine neoplasia [MEN] syndrome NOS
    • type IIA E31.22
• Sipple's syndrome E31.22
• Syndrome - see also Disease
  • Sipple's E31.22

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.