2020 ICD-10-CM Diagnosis Code E34.51

Complete androgen insensitivity syndrome

    2016 2017 2018 2019 2020 Billable/Specific Code
  • E34.51 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM E34.51 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E34.51 - other international versions of ICD-10 E34.51 may differ.
Applicable To
  • Complete androgen insensitivity
  • de Quervain syndrome
  • Goldberg-Maxwell syndrome
The following code(s) above E34.51 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E34.51:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E20-E35
    2020 ICD-10-CM Range E20-E35

    Disorders of other endocrine glands

    Type 1 Excludes
    Disorders of other endocrine glands
  • E34
    ICD-10-CM Diagnosis Code E34

    Other endocrine disorders

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • pseudohypoparathyroidism (E20.1)
    Other endocrine disorders
Approximate Synonyms
  • Testicular feminization
Clinical Information
  • A disorder also known as complete androgen insensitivity syndrome (cais). The 46,xy genetic male totally lacks androgen responsiveness in the target organs thus exhibits a female phenotype.
  • A disorder of sexual development in persons with 46xy karyotype, characterized by an abnormality of the genes encoding androgen receptors. It results in a female sex appearance or the development of both male and female characteristics.
  • Aspects of female morphology in a xy genotype caused by defects in cellular receptors for testosterone and dihydrotestosterone, transmitted as an x-linked trait.
  • Sexual ambiguity in males due to a sexual differentiation disorder caused by testicular failure to respond to androgens. The affected males have abdominal and inguinal testes, female external genitalia and breasts, blind vaginas, and absent uteri. Some patients have absent pubic and axillary hair, hence the synonym "hairless pseudofemale." mental retardation occurs in some cases.
ICD-10-CM E34.51 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 643 Endocrine disorders with mcc
  • 644 Endocrine disorders with cc
  • 645 Endocrine disorders without cc/mcc

Convert E34.51 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to E34.51:
  • De Quervain's
    • syndrome E34.51
  • Goldberg-Maxwell syndrome E34.51
  • Insensitivity
    • androgen E34.50
      ICD-10-CM Diagnosis Code E34.50

      Androgen insensitivity syndrome, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
      Applicable To
      • Androgen insensitivity NOS
      • complete E34.51
  • Pseudohermaphroditism Q56.3
    ICD-10-CM Diagnosis Code Q56.3

    Pseudohermaphroditism, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code POA Exempt
    • male Q56.1
      ICD-10-CM Diagnosis Code Q56.1

      Male pseudohermaphroditism, not elsewhere classified

        2016 2017 2018 2019 2020 Billable/Specific Code Male Dx POA Exempt
      Applicable To
      • 46, XY with streak gonads
      • Male pseudohermaphroditism NOS
      • with
        • androgen resistance E34.51
        • feminizing testis E34.51
  • Syndrome - see also Disease
    • androgen insensitivity E34.50
      ICD-10-CM Diagnosis Code E34.50

      Androgen insensitivity syndrome, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
      Applicable To
      • Androgen insensitivity NOS
      • complete E34.51
    • De Quervain E34.51
    • Goldberg-Maxwell E34.51
    • testicular feminization E34.51 - see also Syndrome, androgen insensitivity
  • Testicle, testicular, testis - see also condition

ICD-10-CM Codes Adjacent To E34.51
E32.8 Other diseases of thymus
E32.9 Disease of thymus, unspecified
E34 Other endocrine disorders
E34.0 Carcinoid syndrome
E34.1 Other hypersecretion of intestinal hormones
E34.2 Ectopic hormone secretion, not elsewhere classified
E34.3 Short stature due to endocrine disorder
E34.4 Constitutional tall stature
E34.5 Androgen insensitivity syndrome
E34.50 …… unspecified
E34.51 Complete androgen insensitivity syndrome
E34.52 Partial androgen insensitivity syndrome
E34.8 Other specified endocrine disorders
E34.9 Endocrine disorder, unspecified
E35 Disorders of endocrine glands in diseases classified elsewhere
E36 Intraoperative complications of endocrine system
E36.0 Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating a procedure
E36.01 Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating an endocrine system procedure
E36.02 Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating other procedure
E36.1 Accidental puncture and laceration of an endocrine system organ or structure during a procedure
E36.11 Accidental puncture and laceration of an endocrine system organ or structure during an endocrine system procedure

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.