2022 ICD-10-CM Diagnosis Code E43

Unspecified severe protein-calorie malnutrition

    2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
  • E43 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2022 edition of ICD-10-CM E43 became effective on October 1, 2021.
  • This is the American ICD-10-CM version of E43 - other international versions of ICD-10 E43 may differ.
Applicable To
  • Starvation edema
The following code(s) above E43 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E43:
  • E00-E89
    2022 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E40-E46
    2022 ICD-10-CM Range E40-E46

    Malnutrition

    Type 1 Excludes
    • intestinal malabsorption (K90.-)
    • sequelae of protein-calorie malnutrition (E64.0)
    Type 2 Excludes
    Malnutrition
Approximate Synonyms
  • Diabetes type 1 with severe malnutrition
  • Diabetes type 2 with severe malnutrition
  • Edema due to nutritional deficiency
  • Nutritional edema
  • Protein calorie malnutrition, severe
  • Severe malnutrition due to type 1 diabetes mellitus
  • Severe malnutrition due to type 2 diabetes mellitus
  • Severe protein-calorie malnutrition (gomez: less than 60% of standard weight)
ICD-10-CM E43 is grouped within Diagnostic Related Group(s) (MS-DRG v39.0):
  • 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
  • 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems

Convert E43 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
Code annotations containing back-references to E43:
  • Note: E64
    ICD-10-CM Diagnosis Code E64

    Sequelae of malnutrition and other nutritional deficiencies

      2016 2017 2018 2019 2020 2021 2022 Non-Billable/Non-Specific Code
    Code First
    • condition resulting from (sequela) of malnutrition and other nutritional deficiencies
    Note
    • This category is to be used to indicate conditions in categories E43, E44, E46, E50-E63 as the cause of sequelae, which are themselves classified elsewhere. The 'sequelae' include conditions specified as such; they also include the late effects of diseases classifiable to the above categories if the disease itself is no longer present

Diagnosis Index entries containing back-references to E43:
  • Anasarca R60.1
    ICD-10-CM Diagnosis Code R60.1

    Generalized edema

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Type 2 Excludes
    • nutritional E43
  • Atrophy, atrophic (of)
  • Deficiency, deficient
  • Disease, diseased - see also Syndrome
    • wasting NEC R64
      ICD-10-CM Diagnosis Code R64

      Cachexia

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      Applicable To
      • Wasting syndrome
      Code First
      • underlying condition, if known
      Type 1 Excludes
      • abnormal weight loss (R63.4)
      • nutritional marasmus (E41)
  • Emaciation R64
    ICD-10-CM Diagnosis Code R64

    Cachexia

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Wasting syndrome
    Code First
    • underlying condition, if known
    Type 1 Excludes
    • abnormal weight loss (R63.4)
    • nutritional marasmus (E41)
    • due to malnutrition E43
  • Malnutrition E46
    ICD-10-CM Diagnosis Code E46

    Unspecified protein-calorie malnutrition

      2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
    Applicable To
    • Malnutrition NOS
    • Protein-calorie imbalance NOS
    Type 1 Excludes
    • nutritional deficiency NOS (E63.9)
    • degree
      • severe (protein-energy) E43
      • third E43
    • protein E46
      ICD-10-CM Diagnosis Code E46

      Unspecified protein-calorie malnutrition

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      Applicable To
      • Malnutrition NOS
      • Protein-calorie imbalance NOS
      Type 1 Excludes
      • nutritional deficiency NOS (E63.9)
      • calorie E46
        ICD-10-CM Diagnosis Code E46

        Unspecified protein-calorie malnutrition

          2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
        Applicable To
        • Malnutrition NOS
        • Protein-calorie imbalance NOS
        Type 1 Excludes
        • nutritional deficiency NOS (E63.9)
      • energy E46
        ICD-10-CM Diagnosis Code E46

        Unspecified protein-calorie malnutrition

          2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
        Applicable To
        • Malnutrition NOS
        • Protein-calorie imbalance NOS
        Type 1 Excludes
        • nutritional deficiency NOS (E63.9)
    • severe (protein-energy) E43
  • Wasting
    • disease R64
      ICD-10-CM Diagnosis Code R64

      Cachexia

        2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code
      Applicable To
      • Wasting syndrome
      Code First
      • underlying condition, if known
      Type 1 Excludes
      • abnormal weight loss (R63.4)
      • nutritional marasmus (E41)
    • extreme (due to malnutrition) E43

ICD-10-CM Codes Adjacent To E43
E36.0 Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating a procedure
E36.01 Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating an endocrine system procedure
E36.02 Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating other procedure
E36.1 Accidental puncture and laceration of an endocrine system organ or structure during a procedure
E36.11 Accidental puncture and laceration of an endocrine system organ or structure during an endocrine system procedure
E36.12 Accidental puncture and laceration of an endocrine system organ or structure during other procedure
E36.8 Other intraoperative complications of endocrine system
E40 Kwashiorkor
E41 Nutritional marasmus
E42 Marasmic kwashiorkor
E43 Unspecified severe protein-calorie malnutrition
E44 Protein-calorie malnutrition of moderate and mild degree
E44.0 Moderate protein-calorie malnutrition
E44.1 Mild protein-calorie malnutrition
E45 Retarded development following protein-calorie malnutrition
E46 Unspecified protein-calorie malnutrition
E50 Vitamin A deficiency
E50.0 Vitamin A deficiency with conjunctival xerosis
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
E50.2 Vitamin A deficiency with corneal xerosis
E50.3 Vitamin A deficiency with corneal ulceration and xerosis

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.