2020 ICD-10-CM Diagnosis Code E50.8

Other manifestations of vitamin A deficiency

    2016 2017 2018 2019 2020 Billable/Specific Code
  • E50.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM E50.8 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E50.8 - other international versions of ICD-10 E50.8 may differ.
Applicable To
  • Follicular keratosis
  • Xeroderma
The following code(s) above E50.8 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E50.8:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E50-E64
    2020 ICD-10-CM Range E50-E64

    Other nutritional deficiencies

    Type 2 Excludes
    Other nutritional deficiencies
  • E50
    ICD-10-CM Diagnosis Code E50

    Vitamin A deficiency

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • sequelae of vitamin A deficiency (E64.1)
    Vitamin A deficiency
Clinical Information
  • A non-neoplastic disorder characterized by abnormally dry skin. Causes include vitamin a deficiency, sunlight exposure, medications, metabolic disorders, autoimmune disorders, and hereditary genetic disorders.
  • An autosomal dominant inherited chronic skin disorder caused by mutations in the atp2a2 gene. It is characterized by the development of yellow-brown keratotic skin papules in the neck, ears, forehead, chest, back and groin. It is associated with fragility of the free margins of the nails.
  • An autosomal dominantly inherited skin disorder characterized by warty malodorous papules that coalesce into plaques. It is caused by mutations in the atp2a2 gene encoding serca2 protein, one of the sarcoplasmic reticulum calcium-transporting atpases. The condition is similar, clinically and histologically, to benign familial pemphigus, another autosomal dominant skin disorder. Both diseases have defective calcium pumps (calcium-transporting atpases) and unstable desmosomal adhesion junctions (desmosomes) between keratinocytes.
  • Slowly progressive autosomal dominant disorder of keratinization with papules on the seborrheic areas of the body that coalesce to form plaques which may become crusted and secondarily infected; lesions may darken and fuse over time to form papillomatous and warty malodorous growths.
ICD-10-CM E50.8 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
  • 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc

Convert E50.8 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
Code annotations containing back-references to E50.8:
  • Type 1 Excludes: L86
    , L86
    , L86
    ICD-10-CM Diagnosis Code L86

    Keratoderma in diseases classified elsewhere

      2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code
    Code First
    • underlying disease, such as:
    • Reiter's disease (M02.3-)
    Type 1 Excludes
    • gonococcal keratoderma (A54.89)
    • gonococcal keratosis (A54.89)
    • keratoderma due to vitamin A deficiency (E50.8)
    • keratosis due to vitamin A deficiency (E50.8)
    • xeroderma due to vitamin A deficiency (E50.8)
    ICD-10-CM Diagnosis Code L86

    Keratoderma in diseases classified elsewhere

      2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code
    Code First
    • underlying disease, such as:
    • Reiter's disease (M02.3-)
    Type 1 Excludes
    • gonococcal keratoderma (A54.89)
    • gonococcal keratosis (A54.89)
    • keratoderma due to vitamin A deficiency (E50.8)
    • keratosis due to vitamin A deficiency (E50.8)
    • xeroderma due to vitamin A deficiency (E50.8)
    ICD-10-CM Diagnosis Code L86

    Keratoderma in diseases classified elsewhere

      2016 2017 2018 2019 2020 Billable/Specific Code Manifestation Code
    Code First
    • underlying disease, such as:
    • Reiter's disease (M02.3-)
    Type 1 Excludes
    • gonococcal keratoderma (A54.89)
    • gonococcal keratosis (A54.89)
    • keratoderma due to vitamin A deficiency (E50.8)
    • keratosis due to vitamin A deficiency (E50.8)
    • xeroderma due to vitamin A deficiency (E50.8)

Diagnosis Index entries containing back-references to E50.8:
  • Deficiency, deficient
    • vitamin (multiple) E56.9
      ICD-10-CM Diagnosis Code E56.9

      Vitamin deficiency, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
      • A E50.9
        ICD-10-CM Diagnosis Code E50.9

        Vitamin A deficiency, unspecified

          2016 2017 2018 2019 2020 Billable/Specific Code
        Applicable To
        • Hypovitaminosis A NOS
        • with
          • follicular keratosis E50.8
          • manifestations NEC E50.8
          • xeroderma E50.8
  • Keratosis L57.0
    ICD-10-CM Diagnosis Code L57.0

    Actinic keratosis

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Keratosis NOS
    • Senile keratosis
    • Solar keratosis
    • follicularis Q82.8
      ICD-10-CM Diagnosis Code Q82.8

      Other specified congenital malformations of skin

        2016 2017 2018 2019 2020 Billable/Specific Code POA Exempt
      Applicable To
      • Abnormal palmar creases
      • Accessory skin tags
      • Benign familial pemphigus [Hailey-Hailey]
      • Congenital poikiloderma
      • Cutis laxa (hyperelastica)
      • Dermatoglyphic anomalies
      • Inherited keratosis palmaris et plantaris
      • Keratosis follicularis [Darier-White]
      Type 1 Excludes
      • Ehlers-Danlos syndrome (Q79.6-)
      • vitamin A deficiency E50.8
    • vitamin A deficiency E50.8
  • Phrynoderma E50.8 (vitamin A deficiency)
  • Xeroderma - see also Ichthyosis
    • vitamin A deficiency E50.8

ICD-10-CM Codes Adjacent To E50.8
E46 Unspecified protein-calorie malnutrition
E50 Vitamin A deficiency
E50.0 Vitamin A deficiency with conjunctival xerosis
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
E50.2 Vitamin A deficiency with corneal xerosis
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
E50.4 Vitamin A deficiency with keratomalacia
E50.5 Vitamin A deficiency with night blindness
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
E50.7 Other ocular manifestations of vitamin A deficiency
E50.8 Other manifestations of vitamin A deficiency
E50.9 Vitamin A deficiency, unspecified
E51 Thiamine deficiency
E51.1 Beriberi
E51.11 Dry beriberi
E51.12 Wet beriberi
E51.2 Wernicke's encephalopathy
E51.8 Other manifestations of thiamine deficiency
E51.9 Thiamine deficiency, unspecified
E52 Niacin deficiency [pellagra]
E53 Deficiency of other B group vitamins

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.