1. ICD-10-CM Codes
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2. E00-E89 Endocrine, nutritional and metabolic diseases
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3. E50-E64 Other nutritional deficiencies
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4. E50- Vitamin A deficiency
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5. 2021 ICD-10-CM Diagnosis Code E50.8

2021 ICD-10-CM Diagnosis Code E50.8

Other manifestations of vitamin A deficiency

2016 2017 2018 2019 2020 2021 Billable/Specific Code

• E50.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
• The 2021 edition of ICD-10-CM E50.8 became effective on October 1, 2020.
• This is the American ICD-10-CM version of E50.8 - other international versions of ICD-10 E50.8 may differ.

• A non-neoplastic disorder characterized by abnormally dry skin. Causes include vitamin a deficiency, sunlight exposure, medications, metabolic disorders, autoimmune disorders, and hereditary genetic disorders.
• An autosomal dominant inherited chronic skin disorder caused by mutations in the atp2a2 gene. It is characterized by the development of yellow-brown keratotic skin papules in the neck, ears, forehead, chest, back and groin. It is associated with fragility of the free margins of the nails.
• An autosomal dominantly inherited skin disorder characterized by warty malodorous papules that coalesce into plaques. It is caused by mutations in the atp2a2 gene encoding serca2 protein, one of the sarcoplasmic reticulum calcium-transporting atpases. The condition is similar, clinically and histologically, to benign familial pemphigus, another autosomal dominant skin disorder. Both diseases have defective calcium pumps (calcium-transporting atpases) and unstable desmosomal adhesion junctions (desmosomes) between keratinocytes.
• Slowly progressive autosomal dominant disorder of keratinization with papules on the seborrheic areas of the body that coalesce to form plaques which may become crusted and secondarily infected; lesions may darken and fuse over time to form papillomatous and warty malodorous growths.

• 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
• 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc

Convert E50.8 to ICD-9-CM

• 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
• 2017 (effective 10/1/2016): No change
• 2018 (effective 10/1/2017): No change
• 2019 (effective 10/1/2018): No change
• 2020 (effective 10/1/2019): No change
• 2021 (effective 10/1/2020): No change

• Type 1 Excludes: L86
  , L86
  , L86
  ICD-10-CM Diagnosis Code L86

  Keratoderma in diseases classified elsewhere

  2016 2017 2018 2019 2020 2021 Billable/Specific Code Manifestation Code

  Code First

  • underlying disease, such as:
  • Reiter's disease (M02.3-)

  Type 1 Excludes

  • gonococcal keratoderma (A54.89)
  • gonococcal keratosis (A54.89)
  • keratoderma due to vitamin A deficiency (E50.8)
  • keratosis due to vitamin A deficiency (E50.8)
  • xeroderma due to vitamin A deficiency (E50.8)
  ICD-10-CM Diagnosis Code L86

  Keratoderma in diseases classified elsewhere

  2016 2017 2018 2019 2020 2021 Billable/Specific Code Manifestation Code

  Code First

  • underlying disease, such as:
  • Reiter's disease (M02.3-)

  Type 1 Excludes

  • gonococcal keratoderma (A54.89)
  • gonococcal keratosis (A54.89)
  • keratoderma due to vitamin A deficiency (E50.8)
  • keratosis due to vitamin A deficiency (E50.8)
  • xeroderma due to vitamin A deficiency (E50.8)
  ICD-10-CM Diagnosis Code L86

  Keratoderma in diseases classified elsewhere

  2016 2017 2018 2019 2020 2021 Billable/Specific Code Manifestation Code

  Code First

  • underlying disease, such as:
  • Reiter's disease (M02.3-)

  Type 1 Excludes

  • gonococcal keratoderma (A54.89)
  • gonococcal keratosis (A54.89)
  • keratoderma due to vitamin A deficiency (E50.8)
  • keratosis due to vitamin A deficiency (E50.8)
  • xeroderma due to vitamin A deficiency (E50.8)

• Deficiency, deficient
  • vitamin (multiple) E56.9
    ICD-10-CM Diagnosis Code E56.9

    Vitamin deficiency, unspecified

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
    • A E50.9
      ICD-10-CM Diagnosis Code E50.9

      Vitamin A deficiency, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code

      Applicable To

      • Hypovitaminosis A NOS
      • with
        • follicular keratosis E50.8
        • manifestations NEC E50.8
        • xeroderma E50.8
• Keratosis L57.0
  ICD-10-CM Diagnosis Code L57.0

  Actinic keratosis

  2016 2017 2018 2019 2020 2021 Billable/Specific Code

  Applicable To

  • Keratosis NOS
  • Senile keratosis
  • Solar keratosis
  • follicularis Q82.8
    ICD-10-CM Diagnosis Code Q82.8

    Other specified congenital malformations of skin

    2016 2017 2018 2019 2020 2021 Billable/Specific Code POA Exempt

    Applicable To

    • Abnormal palmar creases
    • Accessory skin tags
    • Benign familial pemphigus [Hailey-Hailey]
    • Congenital poikiloderma
    • Cutis laxa (hyperelastica)
    • Dermatoglyphic anomalies
    • Inherited keratosis palmaris et plantaris
    • Keratosis follicularis [Darier-White]

    Type 1 Excludes

    • Ehlers-Danlos syndromes (Q79.6-)
    • vitamin A deficiency E50.8
  • vitamin A deficiency E50.8
• Phrynoderma E50.8 (vitamin A deficiency)
• Xeroderma - see also Ichthyosis
  • vitamin A deficiency E50.8

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.