2019 ICD-10-CM Diagnosis Code E52

Niacin deficiency [pellagra]

    2016 2017 2018 2019 Billable/Specific Code
  • E52 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2019 edition of ICD-10-CM E52 became effective on October 1, 2018.
  • This is the American ICD-10-CM version of E52 - other international versions of ICD-10 E52 may differ.
Applicable To
  • Niacin (-tryptophan) deficiency
  • Nicotinamide deficiency
  • Pellagra (alcoholic)
Type 1 Excludes
Type 1 Excludes Help
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as E52. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • sequelae of niacin deficiency (
    ICD-10-CM Diagnosis Code E64.8

    Sequelae of other nutritional deficiencies

      2016 2017 2018 2019 Billable/Specific Code POA Exempt
    E64.8
    )
The following code(s) above E52 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E52:
  • E00-E89
    2019 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E50-E64
    2019 ICD-10-CM Range E50-E64

    Other nutritional deficiencies

    Type 2 Excludes
    Other nutritional deficiencies
Approximate Synonyms
  • Niacin deficiency
  • Pellagra
Clinical Information
  • A disease due to deficiency of niacin, a b-complex vitamin, or its precursor tryptophan. It is characterized by scaly dermatitis which is often associated with diarrhea and dementia (the three d's).
ICD-10-CM E52 is grouped within Diagnostic Related Group(s) (MS-DRG v36.0):
  • 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
  • 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc

Convert E52 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
Code annotations containing back-references to E52:
  • Code First: F02
    ICD-10-CM Diagnosis Code F02

    Dementia in other diseases classified elsewhere

      2016 2017 2018 2019 Non-Billable/Non-Specific Code
    Code First
    • the underlying physiological condition, such as:
    • Alzheimer's (G30.-)
    • cerebral lipidosis (E75.4)
    • Creutzfeldt-Jakob disease (A81.0-)
    • dementia with Lewy bodies (G31.83)
    • dementia with Parkinsonism (G31.83)
    • epilepsy and recurrent seizures (G40.-)
    • frontotemporal dementia (G31.09)
    • hepatolenticular degeneration (E83.0)
    • human immunodeficiency virus [HIV] disease (B20)
    • Huntington's disease (G10)
    • hypercalcemia (E83.52)
    • hypothyroidism, acquired (E00-E03.-)
    • intoxications (T36-T65)
    • Jakob-Creutzfeldt disease (A81.0-)
    • multiple sclerosis (G35)
    • neurosyphilis (A52.17)
    • niacin deficiency [pellagra] (E52)
    • Parkinson's disease (G20)
    • Pick's disease (G31.01)
    • polyarteritis nodosa (M30.0)
    • prion disease (A81.9)
    • systemic lupus erythematosus (M32.-)
    • traumatic brain injury (S06.-)
    • trypanosomiasis (B56.-, B57.-)
    • vitamin B deficiency (E53.8)
    Includes
    • Major neurocognitive disorder in other diseases classified elsewhere
    Type 2 Excludes
    • dementia in alcohol and psychoactive substance disorders (F10-F19, with .17, .27, .97)
    • vascular dementia (F01.5-)

Diagnosis Index entries containing back-references to E52:
  • Acid
  • Alcohol, alcoholic, alcohol-induced
    • pellagra E52
  • Avitaminosis (multiple) E56.9
    - see also Deficiency, vitamin
    ICD-10-CM Diagnosis Code E56.9

    Vitamin deficiency, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    • B E53.9
      ICD-10-CM Diagnosis Code E53.9

      Vitamin B deficiency, unspecified

        2016 2017 2018 2019 Billable/Specific Code
    • nicotinic acid E52
  • Cheilosis (angular) K13.0
    ICD-10-CM Diagnosis Code K13.0

    Diseases of lips

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Abscess of lips
    • Angular cheilitis
    • Cellulitis of lips
    • Cheilitis NOS
    • Cheilodynia
    • Cheilosis
    • Exfoliative cheilitis
    • Fistula of lips
    • Glandular cheilitis
    • Hypertrophy of lips
    • Perlèche NEC
    Type 1 Excludes
    • ariboflavinosis (E53.0)
    • cheilitis due to radiation-related disorders (L55-L59)
    • congenital fistula of lips (Q38.0)
    • congenital hypertrophy of lips (Q18.6)
    • Perlèche due to candidiasis (B37.83)
    • Perlèche due to riboflavin deficiency (E53.0)
    • with pellagra E52
  • Deficiency, deficient
    • vitamin (multiple) E56.9
      ICD-10-CM Diagnosis Code E56.9

      Vitamin deficiency, unspecified

        2016 2017 2018 2019 Billable/Specific Code
      • B (complex) E53.9
        ICD-10-CM Diagnosis Code E53.9

        Vitamin B deficiency, unspecified

          2016 2017 2018 2019 Billable/Specific Code
      • nicotinic E52
      • PP E52 (pellagra-preventing)
    • niacin E52 (amide) (-tryptophan)
    • nicotinamide E52
    • nicotinic acid E52
  • Dementia (degenerative (primary)) (old age) (persisting) F03.90
    ICD-10-CM Diagnosis Code F03.90

    Unspecified dementia without behavioral disturbance

      2016 2017 2018 2019 Billable/Specific Code Adult Dx (15-124 years)
    Applicable To
    • Dementia NOS
  • Dermatitis (eczematous) L30.9
    ICD-10-CM Diagnosis Code L30.9

    Dermatitis, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Eczema NOS
    • pellagrous E52
  • Encephalopathy (acute) G93.40
    ICD-10-CM Diagnosis Code G93.40

    Encephalopathy, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    • pellagrous E52
  • Erythema, erythematous (infectional) (inflammation) L53.9
    ICD-10-CM Diagnosis Code L53.9

    Erythematous condition, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Erythema NOS
    • Erythroderma NOS
    • endemic E52
  • Gingivitis K05.10
    ICD-10-CM Diagnosis Code K05.10

    Chronic gingivitis, plaque induced

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Chronic gingivitis NOS
    • Gingivitis NOS
  • Glossitis (chronic superficial) (gangrenous) (Moeller's) K14.0
    ICD-10-CM Diagnosis Code K14.0

    Glossitis

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Abscess of tongue
    • Ulceration (traumatic) of tongue
    Type 1 Excludes
    • atrophic glossitis (K14.4)
    • pellagrous E52
  • Niacin E52 (amide)
  • Nicotinic acid deficiency E52
  • Pellagra E52 (alcoholic) (with polyneuropathy)
  • Polioencephalopathy, superior hemorrhagic E51.2
    ICD-10-CM Diagnosis Code E51.2

    Wernicke's encephalopathy

      2016 2017 2018 2019 Billable/Specific Code
  • Polyneuropathy (peripheral) G62.9
    ICD-10-CM Diagnosis Code G62.9

    Polyneuropathy, unspecified

      2016 2017 2018 2019 Billable/Specific Code
    Applicable To
    • Neuropathy NOS
    • in (due to)
      • pellagra E52
  • Syndrome - see also Disease
    • pellagroid E52

ICD-10-CM Codes Adjacent To E52
E50.7 Other ocular manifestations of vitamin A deficiency
E50.8 Other manifestations of vitamin A deficiency
E50.9 Vitamin A deficiency, unspecified
E51 Thiamine deficiency
E51.1 Beriberi
E51.11 Dry beriberi
E51.12 Wet beriberi
E51.2 Wernicke's encephalopathy
E51.8 Other manifestations of thiamine deficiency
E51.9 Thiamine deficiency, unspecified
E52 Niacin deficiency [pellagra]
E53 Deficiency of other B group vitamins
E53.0 Riboflavin deficiency
E53.1 Pyridoxine deficiency
E53.8 Deficiency of other specified B group vitamins
E53.9 Vitamin B deficiency, unspecified
E54 Ascorbic acid deficiency
E55 Vitamin D deficiency
E55.0 Rickets, active
E55.9 Vitamin D deficiency, unspecified
E56 Other vitamin deficiencies

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.