2023 ICD-10-CM Diagnosis Code E53.0

Riboflavin deficiency

    2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
  • E53.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2023 edition of ICD-10-CM E53.0 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of E53.0 - other international versions of ICD-10 E53.0 may differ.
Applicable To
  • Ariboflavinosis
  • Vitamin B2 deficiency
The following code(s) above E53.0 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E53.0:
  • E00-E89
    2023 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E50-E64
    2023 ICD-10-CM Range E50-E64

    Other nutritional deficiencies

    Type 2 Excludes
    Other nutritional deficiencies
  • E53
    ICD-10-CM Diagnosis Code E53

    Deficiency of other B group vitamins

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • sequelae of vitamin B deficiency (E64.8)
    Deficiency of other B group vitamins
Clinical Information
  • A dietary deficiency of riboflavin causing a syndrome chiefly marked by cheilitis, angular stomatitis, glossitis associated with a purplish red or magenta-colored tongue that may show fissures, corneal vascularization, dyssebacia, and anemia. (Dorland, 27th ed)
  • Condition due to a deficiency of riboflavin (vitamin b12) which is associated with inadequate consumption of riboflavin rich foods; produces lesions of skin, digestive tract and nervous system; usually part of a multiple nutrient deficiency.
ICD-10-CM E53.0 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
  • 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc

Convert E53.0 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
Code annotations containing back-references to E53.0:
  • Type 1 Excludes: K13.0
    , K13.0
    ICD-10-CM Diagnosis Code K13.0

    Diseases of lips

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Abscess of lips
    • Angular cheilitis
    • Cellulitis of lips
    • Cheilitis NOS
    • Cheilodynia
    • Cheilosis
    • Exfoliative cheilitis
    • Fistula of lips
    • Glandular cheilitis
    • Hypertrophy of lips
    • Perlèche NEC
    Type 1 Excludes
    • ariboflavinosis (E53.0)
    • cheilitis due to radiation-related disorders (L55-L59)
    • congenital fistula of lips (Q38.0)
    • congenital hypertrophy of lips (Q18.6)
    • Perlèche due to candidiasis (B37.83)
    • Perlèche due to riboflavin deficiency (E53.0)
    ICD-10-CM Diagnosis Code K13.0

    Diseases of lips

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Abscess of lips
    • Angular cheilitis
    • Cellulitis of lips
    • Cheilitis NOS
    • Cheilodynia
    • Cheilosis
    • Exfoliative cheilitis
    • Fistula of lips
    • Glandular cheilitis
    • Hypertrophy of lips
    • Perlèche NEC
    Type 1 Excludes
    • ariboflavinosis (E53.0)
    • cheilitis due to radiation-related disorders (L55-L59)
    • congenital fistula of lips (Q38.0)
    • congenital hypertrophy of lips (Q18.6)
    • Perlèche due to candidiasis (B37.83)
    • Perlèche due to riboflavin deficiency (E53.0)

Diagnosis Index entries containing back-references to E53.0:
  • Ariboflavinosis E53.0
  • Avitaminosis (multiple) E56.9
    - see also Deficiency, vitamin
    ICD-10-CM Diagnosis Code E56.9

    Vitamin deficiency, unspecified

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    • B2 E53.0
    • G E53.0
  • Cheilosis (angular) K13.0
    ICD-10-CM Diagnosis Code K13.0

    Diseases of lips

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Abscess of lips
    • Angular cheilitis
    • Cellulitis of lips
    • Cheilitis NOS
    • Cheilodynia
    • Cheilosis
    • Exfoliative cheilitis
    • Fistula of lips
    • Glandular cheilitis
    • Hypertrophy of lips
    • Perlèche NEC
    Type 1 Excludes
    • ariboflavinosis (E53.0)
    • cheilitis due to radiation-related disorders (L55-L59)
    • congenital fistula of lips (Q38.0)
    • congenital hypertrophy of lips (Q18.6)
    • Perlèche due to candidiasis (B37.83)
    • Perlèche due to riboflavin deficiency (E53.0)
    • due to
      • vitamin B2 E53.0 (riboflavin)
  • Deficiency, deficient
    • vitamin (multiple) E56.9
      ICD-10-CM Diagnosis Code E56.9

      Vitamin deficiency, unspecified

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      • B2 E53.0 (riboflavin)
      • G E53.0
    • riboflavin E53.0 (vitamin B2)
  • Gopalan's syndrome E53.0 (burning feet)
  • Perlèche NEC K13.0
    ICD-10-CM Diagnosis Code K13.0

    Diseases of lips

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Abscess of lips
    • Angular cheilitis
    • Cellulitis of lips
    • Cheilitis NOS
    • Cheilodynia
    • Cheilosis
    • Exfoliative cheilitis
    • Fistula of lips
    • Glandular cheilitis
    • Hypertrophy of lips
    • Perlèche NEC
    Type 1 Excludes
    • ariboflavinosis (E53.0)
    • cheilitis due to radiation-related disorders (L55-L59)
    • congenital fistula of lips (Q38.0)
    • congenital hypertrophy of lips (Q18.6)
    • Perlèche due to candidiasis (B37.83)
    • Perlèche due to riboflavin deficiency (E53.0)
    • due to
      • riboflavin deficiency E53.0
      • vitamin B2 E53.0 (riboflavin)
  • Riboflavin deficiency E53.0
  • Stomatitis (denture) (ulcerative) K12.1
    ICD-10-CM Diagnosis Code K12.1

    Other forms of stomatitis

      2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
    Applicable To
    • Stomatitis NOS
    • Denture stomatitis
    • Ulcerative stomatitis
    • Vesicular stomatitis
    Type 1 Excludes
    • acute necrotizing ulcerative stomatitis (A69.1)
    • Vincent's stomatitis (A69.1)
    • angular K13.0
      ICD-10-CM Diagnosis Code K13.0

      Diseases of lips

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Abscess of lips
      • Angular cheilitis
      • Cellulitis of lips
      • Cheilitis NOS
      • Cheilodynia
      • Cheilosis
      • Exfoliative cheilitis
      • Fistula of lips
      • Glandular cheilitis
      • Hypertrophy of lips
      • Perlèche NEC
      Type 1 Excludes
      • ariboflavinosis (E53.0)
      • cheilitis due to radiation-related disorders (L55-L59)
      • congenital fistula of lips (Q38.0)
      • congenital hypertrophy of lips (Q18.6)
      • Perlèche due to candidiasis (B37.83)
      • Perlèche due to riboflavin deficiency (E53.0)
      • due to dietary or vitamin deficiency E53.0
    • due to

ICD-10-CM Codes Adjacent To E53.0
E50.9 Vitamin A deficiency, unspecified
E51 Thiamine deficiency
E51.1 Beriberi
E51.11 Dry beriberi
E51.12 Wet beriberi
E51.2 Wernicke's encephalopathy
E51.8 Other manifestations of thiamine deficiency
E51.9 Thiamine deficiency, unspecified
E52 Niacin deficiency [pellagra]
E53 Deficiency of other B group vitamins
E53.0 Riboflavin deficiency
E53.1 Pyridoxine deficiency
E53.8 Deficiency of other specified B group vitamins
E53.9 Vitamin B deficiency, unspecified
E54 Ascorbic acid deficiency
E55 Vitamin D deficiency
E55.0 Rickets, active
E55.9 Vitamin D deficiency, unspecified
E56 Other vitamin deficiencies
E56.0 Deficiency of vitamin E
E56.1 Deficiency of vitamin K

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.