2020 ICD-10-CM Diagnosis Code E74.19

Other disorders of fructose metabolism

    2016 2017 2018 2019 2020 Billable/Specific Code
  • E74.19 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM E74.19 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E74.19 - other international versions of ICD-10 E74.19 may differ.
Applicable To
  • Fructose-1, 6-diphosphatase deficiency
The following code(s) above E74.19 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E74.19:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E70-E88
    2020 ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • Ehlers-Danlos syndrome (Q79.6-)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    Metabolic disorders
  • E74
    ICD-10-CM Diagnosis Code E74

    Other disorders of carbohydrate metabolism

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    Other disorders of carbohydrate metabolism
  • E74.1
    ICD-10-CM Diagnosis Code E74.1

    Disorders of fructose metabolism

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • muscle phosphofructokinase deficiency (E74.09)
    Disorders of fructose metabolism
Approximate Synonyms
  • Deficiency, fructose 1,6 diphosphatase
  • Fructose-biphosphatase deficiency
Clinical Information
  • An autosomal recessive fructose metabolism disorder due to absent or deficient fructose-1,6-diphosphatase activity. Gluconeogenesis is impaired, resulting in accumulation of gluconeogenic precursors (e.g., amino acids, lactate, ketones) and manifested as hypoglycemia, ketosis, and lactic acidosis. Episodes in the newborn infant are often lethal. Later episodes are often brought on by fasting and febrile infections. As patients age through early childhood, tolerance to fasting improves and development becomes normal.
ICD-10-CM E74.19 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 391 Esophagitis, gastroenteritis and miscellaneous digestive disorders with mcc
  • 392 Esophagitis, gastroenteritis and miscellaneous digestive disorders without mcc

Convert E74.19 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to E74.19:
  • Deficiency, deficient
    • aldolase E74.19 (hereditary)
    • fructose 1,6-diphosphatase E74.19
    • fructose-1-phosphate aldolase E74.19
    • phosphofructokinase E74.19
  • Disorder (of) - see also Disease
    • fructose metabolism E74.10
      ICD-10-CM Diagnosis Code E74.10

      Disorder of fructose metabolism, unspecified

        2016 2017 2018 2019 2020 Billable/Specific Code
      • fructose-1, 6-diphosphatase deficiency E74.19
      • other specified E74.19
  • Fructose 1,6 diphosphatase deficiency E74.19
  • Hyperfructosemia E74.19

ICD-10-CM Codes Adjacent To E74.19
E74.00 …… unspecified
E74.01 von Gierke disease
E74.02 Pompe disease
E74.03 Cori disease
E74.04 McArdle disease
E74.09 Other glycogen storage disease
E74.1 Disorders of fructose metabolism
E74.10 Disorder of fructose metabolism, unspecified
E74.11 Essential fructosuria
E74.12 Hereditary fructose intolerance
E74.19 Other disorders of fructose metabolism
E74.2 Disorders of galactose metabolism
E74.20 …… unspecified
E74.21 Galactosemia
E74.29 Other disorders of galactose metabolism
E74.3 Other disorders of intestinal carbohydrate absorption
E74.31 Sucrase-isomaltase deficiency
E74.39 Other disorders of intestinal carbohydrate absorption
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
E74.8 Other specified disorders of carbohydrate metabolism
E74.9 Disorder of carbohydrate metabolism, unspecified

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.