2021 ICD-10-CM Diagnosis Code E74.31

Sucrase-isomaltase deficiency

    2016 2017 2018 2019 2020 2021 Billable/Specific Code
  • E74.31 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM E74.31 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of E74.31 - other international versions of ICD-10 E74.31 may differ.
The following code(s) above E74.31 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E74.31:
  • E00-E89
    2021 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E70-E88
    2021 ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • Ehlers-Danlos syndromes (Q79.6-)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    Metabolic disorders
  • E74
    ICD-10-CM Diagnosis Code E74

    Other disorders of carbohydrate metabolism

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    Other disorders of carbohydrate metabolism
  • E74.3
    ICD-10-CM Diagnosis Code E74.3

    Other disorders of intestinal carbohydrate absorption

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 2 Excludes
    • lactose intolerance (E73.-)
    Other disorders of intestinal carbohydrate absorption
Approximate Synonyms
  • Sucrase isomaltase deficiency
Clinical Information
  • Characterized by the deficiency or absence of the enzymes sucrase and isomaltase existing at, and usually before birth; this enzyme complex (sucrase-isomaltase) assists in the breakdown of a certain sugar (ie, sucrose) and certain products of starch digestion (dextrins); only evident soon after birth when sucrose or starches, such as found in modified milk formulas with sucrose or polycose, are ingested by an affected infant, breast-fed infants or those on lactose-only formula manifest no symptoms until such time as sucrose (found in fruit juices, solid foods, and/or some medications) is introduced into the diet.
ICD-10-CM E74.31 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 391 Esophagitis, gastroenteritis and miscellaneous digestive disorders with mcc
  • 392 Esophagitis, gastroenteritis and miscellaneous digestive disorders without mcc

Convert E74.31 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to E74.31:
  • Intolerance
    • sucrose E74.31 (-isomaltose)
  • Malabsorption K90.9
    ICD-10-CM Diagnosis Code K90.9

    Intestinal malabsorption, unspecified

      2016 2017 2018 2019 2020 2021 Billable/Specific Code
    • isomaltose E74.31

ICD-10-CM Codes Adjacent To E74.31
E74.1 Disorders of fructose metabolism
E74.10 Disorder of fructose metabolism, unspecified
E74.11 Essential fructosuria
E74.12 Hereditary fructose intolerance
E74.19 Other disorders of fructose metabolism
E74.2 Disorders of galactose metabolism
E74.20 …… unspecified
E74.21 Galactosemia
E74.29 Other disorders of galactose metabolism
E74.3 Other disorders of intestinal carbohydrate absorption
E74.31 Sucrase-isomaltase deficiency
E74.39 Other disorders of intestinal carbohydrate absorption
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
E74.8 Other specified disorders of carbohydrate metabolism
E74.81 Disorders of glucose transport, not elsewhere classified
E74.810 Glucose transporter protein type 1 deficiency
E74.818 Other disorders of glucose transport
E74.819 Disorders of glucose transport, unspecified
E74.89 Other specified disorders of carbohydrate metabolism
E74.9 Disorder of carbohydrate metabolism, unspecified
E75 Disorders of sphingolipid metabolism and other lipid storage disorders

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.