2021

  1. ICD-10-CM Codes
    2. ›
  2. E00-E89 Endocrine, nutritional and metabolic diseases
    3. ›
  3. E70-E88 Metabolic disorders
    4. ›
  4. E78- Disorders of lipoprotein metabolism and other lipidemias
    5. ›
  5. 2021 ICD-10-CM Diagnosis Code E78.00

2021 ICD-10-CM Diagnosis Code E78.00

Pure hypercholesterolemia, unspecified

    2017 - New Code 2018 2019 2020 2021 Billable/Specific Code
  • E78.00 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2021 edition of ICD-10-CM E78.00 became effective on October 1, 2020.
  • This is the American ICD-10-CM version of E78.00 - other international versions of ICD-10 E78.00 may differ.
Applicable To
  • Fredrickson's hyperlipoproteinemia, type IIa
  • Hyperbetalipoproteinemia
  • Low-density-lipoprotein-type [LDL] hyperlipoproteinemia
  • (Pure) hypercholesterolemia NOS
The following code(s) above E78.00 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E78.00:
  • E00-E89
    2021 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E70-E88
    2021 ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • Ehlers-Danlos syndromes (Q79.6-)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    Metabolic disorders
  • E78
    ICD-10-CM Diagnosis Code E78

    Disorders of lipoprotein metabolism and other lipidemias

      2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code
    Type 1 Excludes
    Disorders of lipoprotein metabolism and other lipidemias
ICD-10-CM E78.00 is grouped within Diagnostic Related Group(s) (MS-DRG v38.0):
  • 642 Inborn and other disorders of metabolism

Convert E78.00 to ICD-9-CM

Code History
  • 2017 (effective 10/1/2016): New code
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change

Diagnosis Index entries containing back-references to E78.00:

ICD-10-CM Codes Adjacent To E78.00
E76.3 Mucopolysaccharidosis, unspecified
E76.8 Other disorders of glucosaminoglycan metabolism
E76.9 Glucosaminoglycan metabolism disorder, unspecified
E77 Disorders of glycoprotein metabolism
E77.0 Defects in post-translational modification of lysosomal enzymes
E77.1 Defects in glycoprotein degradation
E77.8 Other disorders of glycoprotein metabolism
E77.9 Disorder of glycoprotein metabolism, unspecified
E78 Disorders of lipoprotein metabolism and other lipidemias
E78.0 Pure hypercholesterolemia
E78.00 …… unspecified
E78.01 Familial hypercholesterolemia
E78.1 Pure hyperglyceridemia
E78.2 Mixed hyperlipidemia
E78.3 Hyperchylomicronemia
E78.4 Other hyperlipidemia
E78.41 Elevated Lipoprotein(a)
E78.49 Other hyperlipidemia
E78.5 Hyperlipidemia, unspecified
E78.6 Lipoprotein deficiency
E78.7 Disorders of bile acid and cholesterol metabolism

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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