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ICD-10-CM Codes
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E00-E89
Endocrine, nutritional and metabolic diseases
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E70-E88
Metabolic disorders
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E78-
Disorders of lipoprotein metabolism and other lipidemias
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2018 ICD-10-CM Diagnosis Code E78.4
Other hyperlipidemia
2016 2017 2018 Billable/Specific Code
- E78.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2018 edition of ICD-10-CM E78.4 became effective on October 1, 2017.
- This is the American ICD-10-CM version of E78.4 - other international versions of ICD-10 E78.4 may differ.
Applicable To- Familial combined hyperlipidemia
The following code(s) above
E78.4 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
- Applicable To annotations, or
- Code Also annotations, or
- Code First annotations, or
- Excludes1 annotations, or
- Excludes2 annotations, or
- Includes annotations, or
- Note annotations, or
- Use Additional annotations
that may be applicable to
E78.4:
- E00-E89
2018 ICD-10-CM Range E00-E89
Endocrine, nutritional and metabolic diseasesNote- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Type 1 Excludes- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
- E70-E88
2018 ICD-10-CM Range E70-E88
Metabolic disordersType 1 Excludes- androgen insensitivity syndrome (E34.5-)
- congenital adrenal hyperplasia (E25.0)
- Ehlers-Danlos syndrome (Q79.6)
- hemolytic anemias attributable to enzyme disorders (D55.-)
- Marfan's syndrome (Q87.4)
- 5-alpha-reductase deficiency (E29.1)
- E78
ICD-10-CM Diagnosis Code E78
Disorders of lipoprotein metabolism and other lipidemias
2016 2017 2018 Non-Billable/Non-Specific Code
- Diabetes type 1 with hyperlipidemia
- Familial combined hyperlipidemia
- Familial hyperalphalipoproteinemia
- Hyperalphalipoproteinemia, familial
- Hyperlipidemia due to type 1 diabetes mellitus
- Hyperlipidemia, familial combined
Clinical Information
- A type of familial lipid metabolism disorder characterized by a variable pattern of elevated plasma cholesterol and/or triglycerides. Multiple genes on different chromosomes may be involved, such as the major late transcription factor (upstream stimulatory factors) on chromosome 1.
ICD-10-CM E78.4 is grouped within Diagnostic Related Group(s) (MS-DRG v35.0):
- 642 Inborn and other disorders of metabolism
Convert E78.4 to ICD-9-CM
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
Code annotations containing back-references to E78.4:
- Hyperlipemia, hyperlipidemia E78.5
ICD-10-CM Diagnosis Code E78.5
Hyperlipidemia, unspecified
2016 2017 2018 Billable/Specific Code
- combined E78.2
ICD-10-CM Diagnosis Code E78.2
Mixed hyperlipidemia
2016 2017 2018 Billable/Specific Code
Applicable To- Broad- or floating-betalipoproteinemia
- Combined hyperlipidemia NOS
- Elevated cholesterol with elevated triglycerides NEC
- Fredrickson's hyperlipoproteinemia, type IIb or III
- Hyperbetalipoproteinemia with prebetalipoproteinemia
- Hypercholesteremia with endogenous hyperglyceridemia
- Hyperlipidemia, group C
- Tubo-eruptive xanthoma
- Xanthoma tuberosum
Type 1 Excludes- cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5)
- familial combined hyperlipidemia (E78.4)
- specified NEC E78.4
ICD-10-CM Codes Adjacent To E78.4
E77.1 Defects in glycoprotein degradation
E77.8 Other disorders of glycoprotein metabolism
E77.9 Disorder of glycoprotein metabolism, unspecified
E78 Disorders of lipoprotein metabolism and other lipidemias
E78.0 Pure hypercholesterolemia
E78.01 Familial hypercholesterolemia
E78.1 Pure hyperglyceridemia
E78.2 Mixed hyperlipidemia
E78.3 Hyperchylomicronemia
E78.4
Other hyperlipidemia
E78.5 Hyperlipidemia, unspecified
E78.6 Lipoprotein deficiency
E78.7 Disorders of bile acid and cholesterol metabolism
E78.70 Disorder of bile acid and cholesterol metabolism, unspecified
E78.72 Smith-Lemli-Opitz syndrome
E78.79 Other disorders of bile acid and cholesterol metabolism
E78.8 Other disorders of lipoprotein metabolism
E78.81 Lipoid dermatoarthritis
E78.89 Other lipoprotein metabolism disorders
Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
