2020 ICD-10-CM Diagnosis Code E85.1

Neuropathic heredofamilial amyloidosis

    2016 2017 2018 2019 2020 Billable/Specific Code
  • E85.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2020 edition of ICD-10-CM E85.1 became effective on October 1, 2019.
  • This is the American ICD-10-CM version of E85.1 - other international versions of ICD-10 E85.1 may differ.
Applicable To
  • Amyloid polyneuropathy (Portuguese)
  • Transthyretin-related (ATTR) familial amyloid polyneuropathy
The following code(s) above E85.1 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E85.1:
  • E00-E89
    2020 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E70-E88
    2020 ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • Ehlers-Danlos syndrome (Q79.6-)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    Metabolic disorders
  • E85
    ICD-10-CM Diagnosis Code E85

    Amyloidosis

      2016 2017 2018 2019 2020 Non-Billable/Non-Specific Code
    Type 2 Excludes
    Amyloidosis
Approximate Synonyms
  • Familial amyloid polyneuropathy
Clinical Information
  • A rare inherited neuropathy characterized by deposition of amyloid in the peripheral nerves.
  • Inherited disorders of the peripheral nervous system associated with the deposition of amyloid in nerve tissue. The different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (prealbumin); apolipoprotein a-i; and gelsolin.
ICD-10-CM E85.1 is grouped within Diagnostic Related Group(s) (MS-DRG v37.0):
  • 545 Connective tissue disorders with mcc
  • 546 Connective tissue disorders with cc
  • 547 Connective tissue disorders without cc/mcc

Convert E85.1 to ICD-9-CM

Code History
  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change

Diagnosis Index entries containing back-references to E85.1:
  • Amyloidosis (generalized) (primary) E85.9
    ICD-10-CM Diagnosis Code E85.9

    Amyloidosis, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    • neuropathic heredofamilial E85.1
    • Portuguese E85.1
  • Polyneuropathy (peripheral) G62.9
    ICD-10-CM Diagnosis Code G62.9

    Polyneuropathy, unspecified

      2016 2017 2018 2019 2020 Billable/Specific Code
    Applicable To
    • Neuropathy NOS
    • amyloid (Portuguese) E85.1
      • transthyretin-related E85.1 (ATTR)
    • in (due to)
      • amyloidosis, familial E85.1 (Portuguese)
    • transthyretin-related (ATTR) E85.1

ICD-10-CM Codes Adjacent To E85.1
E83.9 Disorder of mineral metabolism, unspecified
E84 Cystic fibrosis
E84.0 Cystic fibrosis with pulmonary manifestations
E84.1 Cystic fibrosis with intestinal manifestations
E84.11 Meconium ileus in cystic fibrosis
E84.19 Cystic fibrosis with other intestinal manifestations
E84.8 Cystic fibrosis with other manifestations
E84.9 Cystic fibrosis, unspecified
E85 Amyloidosis
E85.0 Non-neuropathic heredofamilial amyloidosis
E85.1 Neuropathic heredofamilial amyloidosis
E85.2 Heredofamilial amyloidosis, unspecified
E85.3 Secondary systemic amyloidosis
E85.4 Organ-limited amyloidosis
E85.8 Other amyloidosis
E85.81 Light chain (AL) amyloidosis
E85.82 Wild-type transthyretin-related (ATTR) amyloidosis
E85.89 Other amyloidosis
E85.9 Amyloidosis, unspecified
E86 Volume depletion
E86.0 Dehydration

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.