2023 ICD-10-CM Diagnosis Code E87.21

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Acute metabolic acidosis

    2023 - New Code Billable/Specific Code
  • E87.21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • ICD-10-CM E87.21 is a new 2023 ICD-10-CM code that became effective on October 1, 2022.
  • This is the American ICD-10-CM version of E87.21 - other international versions of ICD-10 E87.21 may differ.
Applicable To
  • Acute lactic acidosis
The following code(s) above E87.21 contain annotation back-references
Annotation Back-References
In this context, annotation back-references refer to codes that contain:
  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations
that may be applicable to E87.21:
  • E00-E89
    2023 ICD-10-CM Range E00-E89

    Endocrine, nutritional and metabolic diseases

    Note
    • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
    Type 1 Excludes
    • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
    Endocrine, nutritional and metabolic diseases
  • E70-E88
    2023 ICD-10-CM Range E70-E88

    Metabolic disorders

    Type 1 Excludes
    • androgen insensitivity syndrome (E34.5-)
    • congenital adrenal hyperplasia (E25.0)
    • hemolytic anemias attributable to enzyme disorders (D55.-)
    • Marfan's syndrome (Q87.4)
    • 5-alpha-reductase deficiency (E29.1)
    Type 2 Excludes
    • Ehlers-Danlos syndromes (Q79.6-)
    Metabolic disorders
  • E87
    ICD-10-CM Diagnosis Code E87

    Other disorders of fluid, electrolyte and acid-base balance

      2016 2017 2018 2019 2020 2021 2022 2023 Non-Billable/Non-Specific Code
    Type 1 Excludes
    • diabetes insipidus (E23.2)
    • electrolyte imbalance associated with hyperemesis gravidarum (O21.1)
    • electrolyte imbalance following ectopic or molar pregnancy (O08.5)
    • familial periodic paralysis (G72.3)
    Other disorders of fluid, electrolyte and acid-base balance
  • E87.2
    ICD-10-CM Diagnosis Code E87.2

    Acidosis

      2016 2017 2018 2019 2020 2021 2022 2023 - Converted to Parent Code Non-Billable/Non-Specific Code
    Type 1 Excludes
    • diabetic acidosis - see categories E08-E10, E11, E13 with ketoacidosis
    Acidosis
ICD-10-CM E87.21 is grouped within Diagnostic Related Group(s) (MS-DRG v40.0):
  • 640 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes with mcc
  • 641 Miscellaneous disorders of nutrition, metabolism, fluids and electrolytes without mcc
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems
Code History
  • 2023 (effective 10/1/2022): New code

Diagnosis Index entries containing back-references to E87.21:
  • Acidosis (lactic) E87.20
    ICD-10-CM Diagnosis Code E87.20

    Acidosis, unspecified

      2023 - New Code Billable/Specific Code
    Applicable To
    • Lactic acidosis NOS
    • Metabolic acidosis NOS
    Code Also
    • , if applicable, respiratory failure with hypercapnia (J96. with 5th character 2)
    • lactic E87.20
      ICD-10-CM Diagnosis Code E87.20

      Acidosis, unspecified

        2023 - New Code Billable/Specific Code
      Applicable To
      • Lactic acidosis NOS
      • Metabolic acidosis NOS
      Code Also
      • , if applicable, respiratory failure with hypercapnia (J96. with 5th character 2)
      • acute E87.21
    • metabolic NEC E87.20
      ICD-10-CM Diagnosis Code E87.20

      Acidosis, unspecified

        2023 - New Code Billable/Specific Code
      Applicable To
      • Lactic acidosis NOS
      • Metabolic acidosis NOS
      Code Also
      • , if applicable, respiratory failure with hypercapnia (J96. with 5th character 2)
      • acute E87.21
  • Disorder (of) - see also Disease
    • electrolyte (balance) E87.8
      ICD-10-CM Diagnosis Code E87.8

      Other disorders of electrolyte and fluid balance, not elsewhere classified

        2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code
      Applicable To
      • Electrolyte imbalance NOS
      • Hyperchloremia
      • Hypochloremia
      • acidosis (lactic) (metabolic) E87.20
        ICD-10-CM Diagnosis Code E87.20

        Acidosis, unspecified

          2023 - New Code Billable/Specific Code
        Applicable To
        • Lactic acidosis NOS
        • Metabolic acidosis NOS
        Code Also
        • , if applicable, respiratory failure with hypercapnia (J96. with 5th character 2)
        • acute E87.21

ICD-10-CM Codes Adjacent To E87.21
E85.9 Amyloidosis, unspecified
E86 Volume depletion
E86.0 Dehydration
E86.1 Hypovolemia
E86.9 Volume depletion, unspecified
E87 Other disorders of fluid, electrolyte and acid-base balance
E87.0 Hyperosmolality and hypernatremia
E87.1 Hypo-osmolality and hyponatremia
E87.2 Acidosis
E87.20 …… unspecified
E87.21 Acute metabolic acidosis
E87.22 Chronic metabolic acidosis
E87.29 Other acidosis
E87.3 Alkalosis
E87.4 Mixed disorder of acid-base balance
E87.5 Hyperkalemia
E87.6 Hypokalemia
E87.7 Fluid overload
E87.70 …… unspecified
E87.71 Transfusion associated circulatory overload
E87.79 Other fluid overload

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.